Anticholinesterase activity evaluation of alkaloids and coumarin from stems of Conchocarpus fontanesianus

Detalhes bibliográficos
Autor(a) principal: Cabral,Rodrigo S.
Data de Publicação: 2012
Outros Autores: Sartori,Maura C., Cordeiro,Inês, Queiroga,Carmen L., Eberlin,Marcos N., Lago,João H. G., Moreno,Paulo R. H., Young,Maria C. M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2012000200018
Resumo: Conchocarpus fontanesianus (A. St.-Hill.) Kallunki & Pirani, Rutaceae, popularly known as pitaguará, is a native and endemic tree from São Paulo and Rio de Janeiro States, Brazil. Based in the information that anticholinesterasic derivatives could act as new prototypes to treatment of Alzheimer disease, this work describes the fractionation guided by evaluation of the anticholinesterase activity of the ethanolic stems extract from C. fontanesianus. This procedure afforded the alkaloids dictamnine (1), γ-fagarine (2), skimianine (3), and 2-phenyl-1-methyl-4-quinolone (4), as well as the coumarin marmesin (5).
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spelling Anticholinesterase activity evaluation of alkaloids and coumarin from stems of Conchocarpus fontanesianusacetylcholinesterase inhibitors, alkaloidsConchocarpus fontanesianuscoumarin RutaceaeConchocarpus fontanesianus (A. St.-Hill.) Kallunki & Pirani, Rutaceae, popularly known as pitaguará, is a native and endemic tree from São Paulo and Rio de Janeiro States, Brazil. Based in the information that anticholinesterasic derivatives could act as new prototypes to treatment of Alzheimer disease, this work describes the fractionation guided by evaluation of the anticholinesterase activity of the ethanolic stems extract from C. fontanesianus. This procedure afforded the alkaloids dictamnine (1), γ-fagarine (2), skimianine (3), and 2-phenyl-1-methyl-4-quinolone (4), as well as the coumarin marmesin (5).Sociedade Brasileira de Farmacognosia2012-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2012000200018Revista Brasileira de Farmacognosia v.22 n.2 2012reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2011005000219info:eu-repo/semantics/openAccessCabral,Rodrigo S.Sartori,Maura C.Cordeiro,InêsQueiroga,Carmen L.Eberlin,Marcos N.Lago,João H. G.Moreno,Paulo R. H.Young,Maria C. M.eng2012-05-08T00:00:00Zoai:scielo:S0102-695X2012000200018Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2012-05-08T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv Anticholinesterase activity evaluation of alkaloids and coumarin from stems of Conchocarpus fontanesianus
title Anticholinesterase activity evaluation of alkaloids and coumarin from stems of Conchocarpus fontanesianus
spellingShingle Anticholinesterase activity evaluation of alkaloids and coumarin from stems of Conchocarpus fontanesianus
Cabral,Rodrigo S.
acetylcholinesterase inhibitors, alkaloids
Conchocarpus fontanesianus
coumarin Rutaceae
title_short Anticholinesterase activity evaluation of alkaloids and coumarin from stems of Conchocarpus fontanesianus
title_full Anticholinesterase activity evaluation of alkaloids and coumarin from stems of Conchocarpus fontanesianus
title_fullStr Anticholinesterase activity evaluation of alkaloids and coumarin from stems of Conchocarpus fontanesianus
title_full_unstemmed Anticholinesterase activity evaluation of alkaloids and coumarin from stems of Conchocarpus fontanesianus
title_sort Anticholinesterase activity evaluation of alkaloids and coumarin from stems of Conchocarpus fontanesianus
author Cabral,Rodrigo S.
author_facet Cabral,Rodrigo S.
Sartori,Maura C.
Cordeiro,Inês
Queiroga,Carmen L.
Eberlin,Marcos N.
Lago,João H. G.
Moreno,Paulo R. H.
Young,Maria C. M.
author_role author
author2 Sartori,Maura C.
Cordeiro,Inês
Queiroga,Carmen L.
Eberlin,Marcos N.
Lago,João H. G.
Moreno,Paulo R. H.
Young,Maria C. M.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Cabral,Rodrigo S.
Sartori,Maura C.
Cordeiro,Inês
Queiroga,Carmen L.
Eberlin,Marcos N.
Lago,João H. G.
Moreno,Paulo R. H.
Young,Maria C. M.
dc.subject.por.fl_str_mv acetylcholinesterase inhibitors, alkaloids
Conchocarpus fontanesianus
coumarin Rutaceae
topic acetylcholinesterase inhibitors, alkaloids
Conchocarpus fontanesianus
coumarin Rutaceae
description Conchocarpus fontanesianus (A. St.-Hill.) Kallunki & Pirani, Rutaceae, popularly known as pitaguará, is a native and endemic tree from São Paulo and Rio de Janeiro States, Brazil. Based in the information that anticholinesterasic derivatives could act as new prototypes to treatment of Alzheimer disease, this work describes the fractionation guided by evaluation of the anticholinesterase activity of the ethanolic stems extract from C. fontanesianus. This procedure afforded the alkaloids dictamnine (1), γ-fagarine (2), skimianine (3), and 2-phenyl-1-methyl-4-quinolone (4), as well as the coumarin marmesin (5).
publishDate 2012
dc.date.none.fl_str_mv 2012-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2012000200018
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2012000200018
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-695X2011005000219
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.22 n.2 2012
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
instname_str Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron_str SBFGNOSIA
institution SBFGNOSIA
reponame_str Revista Brasileira de Farmacognosia (Online)
collection Revista Brasileira de Farmacognosia (Online)
repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
repository.mail.fl_str_mv rbgnosia@ltf.ufpb.br
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