Cornoside and other constituents from the latex of Parahancornia amapa (Hub.) Ducke (Apocynaceae) a medicinal plant in Northern Brazil

• Autor(a) principal: Carvalho,Mário G. de
• Data de Publicação: 2008
• Outros Autores: Albuquerque,Luis A. de, Alves,Cássia C. F., Cascon,Vera
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista Brasileira de Farmacognosia (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2008000500004
• topic: Parahancornia amapa; amapá; phenylethanoids; carbohydrates; cornoside; lupeol esters

Latex of Parahancornia amapa which is known as "amapa milk" in folk medicine was extracted with hexane, dichloromethane and methanol. From the hexane and dichloromethane were identified mixtures of 3-O-acyl lupeol esters such as identified previously. In the methanol extract, a large amount of carbohydrates, the phenylethanoid glucoside known as cornoside, other phenylethanoids derivatives and methylmyoinositol were identified. The analysis of IR, NMR and GC-LRMS of the natural compounds and tetra-acetylcornoside and comparison with literature data were used to identify the compounds.