Vouacapane diterpenoids isolated from Pterodon and their biological activities

Detalhes bibliográficos
Autor(a) principal: Oliveira,Leandra A.R.
Data de Publicação: 2017
Outros Autores: Oliveira,Gerlon A.R., Borges,Leonardo L., Bara,Maria Teresa F., Silveira,Dâmaris
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2017000500663
Resumo: Abstract The Pterodon genus comprises two native species in Brazil, known as “sucupira-branca” or “faveira”. Their fruits have long been used in Brazilian natural medicine, mainly for the treatment of infections and inflammations. The pharmacological properties of these fruits have often been linked with vouacapane diterpenoids. This review evaluated the scientific research in the period from 1973 to February 2017, aiming to answer how difficult it still is to develop a scientifically supported product based on Pterodon vouacapanes. Therefore, this paper reviews purification, identification, and quantification methods applied to vouacapane diterpenoids from Pterodon, as well as the performance of these phytochemicals in pharmacological tests described in the literature. Data analysis results support conventional notions that suggest vouacapane diterpenoids from Pterodon have anti-inflammatory properties. However, the studies carried out so far still represent partial assessment of the vouacapane activities and further studies need to be completed. Pterodon diterpenoids have also been associated with larvicidal, leishmanicidal, cardiovascular, and antitumor activities, which reinforces the genus' potential as a source of phytomedicines. Some remaining gaps about the reviewed activities were mentioned, while trends and perspectives for future research were proposed.
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spelling Vouacapane diterpenoids isolated from Pterodon and their biological activitiesBiological activityPhytochemistrySucupiraVouacapane diterpenoidsAbstract The Pterodon genus comprises two native species in Brazil, known as “sucupira-branca” or “faveira”. Their fruits have long been used in Brazilian natural medicine, mainly for the treatment of infections and inflammations. The pharmacological properties of these fruits have often been linked with vouacapane diterpenoids. This review evaluated the scientific research in the period from 1973 to February 2017, aiming to answer how difficult it still is to develop a scientifically supported product based on Pterodon vouacapanes. Therefore, this paper reviews purification, identification, and quantification methods applied to vouacapane diterpenoids from Pterodon, as well as the performance of these phytochemicals in pharmacological tests described in the literature. Data analysis results support conventional notions that suggest vouacapane diterpenoids from Pterodon have anti-inflammatory properties. However, the studies carried out so far still represent partial assessment of the vouacapane activities and further studies need to be completed. Pterodon diterpenoids have also been associated with larvicidal, leishmanicidal, cardiovascular, and antitumor activities, which reinforces the genus' potential as a source of phytomedicines. Some remaining gaps about the reviewed activities were mentioned, while trends and perspectives for future research were proposed.Sociedade Brasileira de Farmacognosia2017-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2017000500663Revista Brasileira de Farmacognosia v.27 n.5 2017reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1016/j.bjp.2017.05.014info:eu-repo/semantics/openAccessOliveira,Leandra A.R.Oliveira,Gerlon A.R.Borges,Leonardo L.Bara,Maria Teresa F.Silveira,Dâmariseng2017-11-14T00:00:00Zoai:scielo:S0102-695X2017000500663Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2017-11-14T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv Vouacapane diterpenoids isolated from Pterodon and their biological activities
title Vouacapane diterpenoids isolated from Pterodon and their biological activities
spellingShingle Vouacapane diterpenoids isolated from Pterodon and their biological activities
Oliveira,Leandra A.R.
Biological activity
Phytochemistry
Sucupira
Vouacapane diterpenoids
title_short Vouacapane diterpenoids isolated from Pterodon and their biological activities
title_full Vouacapane diterpenoids isolated from Pterodon and their biological activities
title_fullStr Vouacapane diterpenoids isolated from Pterodon and their biological activities
title_full_unstemmed Vouacapane diterpenoids isolated from Pterodon and their biological activities
title_sort Vouacapane diterpenoids isolated from Pterodon and their biological activities
author Oliveira,Leandra A.R.
author_facet Oliveira,Leandra A.R.
Oliveira,Gerlon A.R.
Borges,Leonardo L.
Bara,Maria Teresa F.
Silveira,Dâmaris
author_role author
author2 Oliveira,Gerlon A.R.
Borges,Leonardo L.
Bara,Maria Teresa F.
Silveira,Dâmaris
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Oliveira,Leandra A.R.
Oliveira,Gerlon A.R.
Borges,Leonardo L.
Bara,Maria Teresa F.
Silveira,Dâmaris
dc.subject.por.fl_str_mv Biological activity
Phytochemistry
Sucupira
Vouacapane diterpenoids
topic Biological activity
Phytochemistry
Sucupira
Vouacapane diterpenoids
description Abstract The Pterodon genus comprises two native species in Brazil, known as “sucupira-branca” or “faveira”. Their fruits have long been used in Brazilian natural medicine, mainly for the treatment of infections and inflammations. The pharmacological properties of these fruits have often been linked with vouacapane diterpenoids. This review evaluated the scientific research in the period from 1973 to February 2017, aiming to answer how difficult it still is to develop a scientifically supported product based on Pterodon vouacapanes. Therefore, this paper reviews purification, identification, and quantification methods applied to vouacapane diterpenoids from Pterodon, as well as the performance of these phytochemicals in pharmacological tests described in the literature. Data analysis results support conventional notions that suggest vouacapane diterpenoids from Pterodon have anti-inflammatory properties. However, the studies carried out so far still represent partial assessment of the vouacapane activities and further studies need to be completed. Pterodon diterpenoids have also been associated with larvicidal, leishmanicidal, cardiovascular, and antitumor activities, which reinforces the genus' potential as a source of phytomedicines. Some remaining gaps about the reviewed activities were mentioned, while trends and perspectives for future research were proposed.
publishDate 2017
dc.date.none.fl_str_mv 2017-10-01
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2017000500663
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2017000500663
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.bjp.2017.05.014
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dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.27 n.5 2017
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
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repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
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