Vouacapane diterpenoids isolated from Pterodon and their biological activities

Detalhes bibliográficos
Autor(a) principal: Oliveira, Leandra A.R.
Data de Publicação: 2017
Outros Autores: Oliveira, Gerlon A.R., Borges, Leonardo L., Bara, Maria Teresa F., Silveira, Dâmaris
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UnB
Texto Completo: http://repositorio.unb.br/handle/10482/30657
http://dx.doi.org/10.1016/j.bjp.2017.05.014
Resumo: The Pterodon genus comprises two native species in Brazil, known as “sucupira-branca” or “faveira”. Their fruits have long been used in Brazilian natural medicine, mainly for the treatment of infections and inflammations. The pharmacological properties of these fruits have often been linked with vouacapane diterpenoids. This review evaluated the scientific research in the period from 1973 to February 2017, aiming to answer how difficult it still is to develop a scientifically supported product based on Pterodon vouacapanes. Therefore, this paper reviews purification, identification, and quantification methods applied to vouacapane diterpenoids from Pterodon, as well as the performance of these phytochemicals in pharmacological tests described in the literature. Data analysis results support conventional notions that suggest vouacapane diterpenoids from Pterodon have anti-inflammatory properties. However, the studies carried out so far still represent partial assessment of the vouacapane activities and further studies need to be completed. Pterodon diterpenoids have also been associated with larvicidal, leishmanicidal, cardiovascular, and antitumor activities, which reinforces the genus' potential as a source of phytomedicines. Some remaining gaps about the reviewed activities were mentioned, while trends and perspectives for future research were proposed.
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spelling Vouacapane diterpenoids isolated from Pterodon and their biological activitiesAtividade biológicaFitoquímicaSucupiraThe Pterodon genus comprises two native species in Brazil, known as “sucupira-branca” or “faveira”. Their fruits have long been used in Brazilian natural medicine, mainly for the treatment of infections and inflammations. The pharmacological properties of these fruits have often been linked with vouacapane diterpenoids. This review evaluated the scientific research in the period from 1973 to February 2017, aiming to answer how difficult it still is to develop a scientifically supported product based on Pterodon vouacapanes. Therefore, this paper reviews purification, identification, and quantification methods applied to vouacapane diterpenoids from Pterodon, as well as the performance of these phytochemicals in pharmacological tests described in the literature. Data analysis results support conventional notions that suggest vouacapane diterpenoids from Pterodon have anti-inflammatory properties. However, the studies carried out so far still represent partial assessment of the vouacapane activities and further studies need to be completed. Pterodon diterpenoids have also been associated with larvicidal, leishmanicidal, cardiovascular, and antitumor activities, which reinforces the genus' potential as a source of phytomedicines. Some remaining gaps about the reviewed activities were mentioned, while trends and perspectives for future research were proposed.Sociedade Brasileira de Farmacognosia2018-01-04T19:14:18Z2018-01-04T19:14:18Z2017-09info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfOLIVEIRA, Leandra A.R. et al. Vouacapane diterpenoids isolated from Pterodon and their biological activities. Revista Brasileira de Farmacognosia, Curitiba, v. 27, n. 5, p. 663-672, set./out. 2017. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2017000500663&lng=en&nrm=iso>. Acesso em: 15 fev. 2018. doi: http://dx.doi.org/10.1016/j.bjp.2017.05.014.http://repositorio.unb.br/handle/10482/30657http://dx.doi.org/10.1016/j.bjp.2017.05.014Revista Brasileira de Farmacognosia - This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivative License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited and the work is not changed in any way (CC BY NC ND 4.0). Fonte: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2017000500663&lng=en&nrm=iso. Acesso em: 15 fev. 2018.info:eu-repo/semantics/openAccessOliveira, Leandra A.R.Oliveira, Gerlon A.R.Borges, Leonardo L.Bara, Maria Teresa F.Silveira, Dâmarisengreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNB2023-05-24T00:10:17Zoai:repositorio.unb.br:10482/30657Repositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2023-05-24T00:10:17Repositório Institucional da UnB - Universidade de Brasília (UnB)false
dc.title.none.fl_str_mv Vouacapane diterpenoids isolated from Pterodon and their biological activities
title Vouacapane diterpenoids isolated from Pterodon and their biological activities
spellingShingle Vouacapane diterpenoids isolated from Pterodon and their biological activities
Oliveira, Leandra A.R.
Atividade biológica
Fitoquímica
Sucupira
title_short Vouacapane diterpenoids isolated from Pterodon and their biological activities
title_full Vouacapane diterpenoids isolated from Pterodon and their biological activities
title_fullStr Vouacapane diterpenoids isolated from Pterodon and their biological activities
title_full_unstemmed Vouacapane diterpenoids isolated from Pterodon and their biological activities
title_sort Vouacapane diterpenoids isolated from Pterodon and their biological activities
author Oliveira, Leandra A.R.
author_facet Oliveira, Leandra A.R.
Oliveira, Gerlon A.R.
Borges, Leonardo L.
Bara, Maria Teresa F.
Silveira, Dâmaris
author_role author
author2 Oliveira, Gerlon A.R.
Borges, Leonardo L.
Bara, Maria Teresa F.
Silveira, Dâmaris
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Oliveira, Leandra A.R.
Oliveira, Gerlon A.R.
Borges, Leonardo L.
Bara, Maria Teresa F.
Silveira, Dâmaris
dc.subject.por.fl_str_mv Atividade biológica
Fitoquímica
Sucupira
topic Atividade biológica
Fitoquímica
Sucupira
description The Pterodon genus comprises two native species in Brazil, known as “sucupira-branca” or “faveira”. Their fruits have long been used in Brazilian natural medicine, mainly for the treatment of infections and inflammations. The pharmacological properties of these fruits have often been linked with vouacapane diterpenoids. This review evaluated the scientific research in the period from 1973 to February 2017, aiming to answer how difficult it still is to develop a scientifically supported product based on Pterodon vouacapanes. Therefore, this paper reviews purification, identification, and quantification methods applied to vouacapane diterpenoids from Pterodon, as well as the performance of these phytochemicals in pharmacological tests described in the literature. Data analysis results support conventional notions that suggest vouacapane diterpenoids from Pterodon have anti-inflammatory properties. However, the studies carried out so far still represent partial assessment of the vouacapane activities and further studies need to be completed. Pterodon diterpenoids have also been associated with larvicidal, leishmanicidal, cardiovascular, and antitumor activities, which reinforces the genus' potential as a source of phytomedicines. Some remaining gaps about the reviewed activities were mentioned, while trends and perspectives for future research were proposed.
publishDate 2017
dc.date.none.fl_str_mv 2017-09
2018-01-04T19:14:18Z
2018-01-04T19:14:18Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv OLIVEIRA, Leandra A.R. et al. Vouacapane diterpenoids isolated from Pterodon and their biological activities. Revista Brasileira de Farmacognosia, Curitiba, v. 27, n. 5, p. 663-672, set./out. 2017. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2017000500663&lng=en&nrm=iso>. Acesso em: 15 fev. 2018. doi: http://dx.doi.org/10.1016/j.bjp.2017.05.014.
http://repositorio.unb.br/handle/10482/30657
http://dx.doi.org/10.1016/j.bjp.2017.05.014
identifier_str_mv OLIVEIRA, Leandra A.R. et al. Vouacapane diterpenoids isolated from Pterodon and their biological activities. Revista Brasileira de Farmacognosia, Curitiba, v. 27, n. 5, p. 663-672, set./out. 2017. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2017000500663&lng=en&nrm=iso>. Acesso em: 15 fev. 2018. doi: http://dx.doi.org/10.1016/j.bjp.2017.05.014.
url http://repositorio.unb.br/handle/10482/30657
http://dx.doi.org/10.1016/j.bjp.2017.05.014
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv reponame:Repositório Institucional da UnB
instname:Universidade de Brasília (UnB)
instacron:UNB
instname_str Universidade de Brasília (UnB)
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institution UNB
reponame_str Repositório Institucional da UnB
collection Repositório Institucional da UnB
repository.name.fl_str_mv Repositório Institucional da UnB - Universidade de Brasília (UnB)
repository.mail.fl_str_mv repositorio@unb.br
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