Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista Brasileira de Farmacognosia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000100008 |
Resumo: | Cuscuta racemosa Mart. is a parasitic plant of the Convolvulaceae family, used in popular medicine as an anti-inflammatory and a diuretic, for stomach and hepatic disorders, and for treating fresh wounds. This plant is popularly known as "cipó-chumbo" and "fios-de-ovos". In this study, it was chemically investigated and tested for its antimicrobial activity and cytotoxicity. The flavonoid and tannin content of the dried plant were 2.79% and 2.01%, respectively. Furthermore, the 4'-methoxyquercetin flavanoid compound was isolated from the ethanolic fraction. The minimum inhibiting concentration in the antimicrobial test was 2.0 mg/ml for Staphylococcus aureus, and a DL50 of 0.231 mg/mL was obtained in the cytotoxicity experiment. The fraction directed to alkaloids was able to eliminate 100% of the brine shrimp used for the test. |
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Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosaCuscuta racemosaConvolvulaceaeantimicrobial activitycytotoxicityCuscuta racemosa Mart. is a parasitic plant of the Convolvulaceae family, used in popular medicine as an anti-inflammatory and a diuretic, for stomach and hepatic disorders, and for treating fresh wounds. This plant is popularly known as "cipó-chumbo" and "fios-de-ovos". In this study, it was chemically investigated and tested for its antimicrobial activity and cytotoxicity. The flavonoid and tannin content of the dried plant were 2.79% and 2.01%, respectively. Furthermore, the 4'-methoxyquercetin flavanoid compound was isolated from the ethanolic fraction. The minimum inhibiting concentration in the antimicrobial test was 2.0 mg/ml for Staphylococcus aureus, and a DL50 of 0.231 mg/mL was obtained in the cytotoxicity experiment. The fraction directed to alkaloids was able to eliminate 100% of the brine shrimp used for the test.Sociedade Brasileira de Farmacognosia2011-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000100008Revista Brasileira de Farmacognosia v.21 n.1 2011reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2011005000005info:eu-repo/semantics/openAccessFerraz,Helena O.Silva,Magali G.Carvalho,RuiSuffredini,Ivana B.Kato,Edna T. M.Arakaki,FernandaBacchi,Elfriede M.eng2011-03-28T00:00:00Zoai:scielo:S0102-695X2011000100008Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2011-03-28T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false |
dc.title.none.fl_str_mv |
Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa |
title |
Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa |
spellingShingle |
Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa Ferraz,Helena O. Cuscuta racemosa Convolvulaceae antimicrobial activity cytotoxicity |
title_short |
Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa |
title_full |
Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa |
title_fullStr |
Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa |
title_full_unstemmed |
Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa |
title_sort |
Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa |
author |
Ferraz,Helena O. |
author_facet |
Ferraz,Helena O. Silva,Magali G. Carvalho,Rui Suffredini,Ivana B. Kato,Edna T. M. Arakaki,Fernanda Bacchi,Elfriede M. |
author_role |
author |
author2 |
Silva,Magali G. Carvalho,Rui Suffredini,Ivana B. Kato,Edna T. M. Arakaki,Fernanda Bacchi,Elfriede M. |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Ferraz,Helena O. Silva,Magali G. Carvalho,Rui Suffredini,Ivana B. Kato,Edna T. M. Arakaki,Fernanda Bacchi,Elfriede M. |
dc.subject.por.fl_str_mv |
Cuscuta racemosa Convolvulaceae antimicrobial activity cytotoxicity |
topic |
Cuscuta racemosa Convolvulaceae antimicrobial activity cytotoxicity |
description |
Cuscuta racemosa Mart. is a parasitic plant of the Convolvulaceae family, used in popular medicine as an anti-inflammatory and a diuretic, for stomach and hepatic disorders, and for treating fresh wounds. This plant is popularly known as "cipó-chumbo" and "fios-de-ovos". In this study, it was chemically investigated and tested for its antimicrobial activity and cytotoxicity. The flavonoid and tannin content of the dried plant were 2.79% and 2.01%, respectively. Furthermore, the 4'-methoxyquercetin flavanoid compound was isolated from the ethanolic fraction. The minimum inhibiting concentration in the antimicrobial test was 2.0 mg/ml for Staphylococcus aureus, and a DL50 of 0.231 mg/mL was obtained in the cytotoxicity experiment. The fraction directed to alkaloids was able to eliminate 100% of the brine shrimp used for the test. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000100008 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000100008 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0102-695X2011005000005 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
dc.source.none.fl_str_mv |
Revista Brasileira de Farmacognosia v.21 n.1 2011 reponame:Revista Brasileira de Farmacognosia (Online) instname:Sociedade Brasileira de Farmacognosia (SBFgnosia) instacron:SBFGNOSIA |
instname_str |
Sociedade Brasileira de Farmacognosia (SBFgnosia) |
instacron_str |
SBFGNOSIA |
institution |
SBFGNOSIA |
reponame_str |
Revista Brasileira de Farmacognosia (Online) |
collection |
Revista Brasileira de Farmacognosia (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia) |
repository.mail.fl_str_mv |
rbgnosia@ltf.ufpb.br |
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1752122465603026944 |