Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa

Detalhes bibliográficos
Autor(a) principal: Ferraz,Helena O.
Data de Publicação: 2011
Outros Autores: Silva,Magali G., Carvalho,Rui, Suffredini,Ivana B., Kato,Edna T. M., Arakaki,Fernanda, Bacchi,Elfriede M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000100008
Resumo: Cuscuta racemosa Mart. is a parasitic plant of the Convolvulaceae family, used in popular medicine as an anti-inflammatory and a diuretic, for stomach and hepatic disorders, and for treating fresh wounds. This plant is popularly known as "cipó-chumbo" and "fios-de-ovos". In this study, it was chemically investigated and tested for its antimicrobial activity and cytotoxicity. The flavonoid and tannin content of the dried plant were 2.79% and 2.01%, respectively. Furthermore, the 4'-methoxyquercetin flavanoid compound was isolated from the ethanolic fraction. The minimum inhibiting concentration in the antimicrobial test was 2.0 mg/ml for Staphylococcus aureus, and a DL50 of 0.231 mg/mL was obtained in the cytotoxicity experiment. The fraction directed to alkaloids was able to eliminate 100% of the brine shrimp used for the test.
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spelling Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosaCuscuta racemosaConvolvulaceaeantimicrobial activitycytotoxicityCuscuta racemosa Mart. is a parasitic plant of the Convolvulaceae family, used in popular medicine as an anti-inflammatory and a diuretic, for stomach and hepatic disorders, and for treating fresh wounds. This plant is popularly known as "cipó-chumbo" and "fios-de-ovos". In this study, it was chemically investigated and tested for its antimicrobial activity and cytotoxicity. The flavonoid and tannin content of the dried plant were 2.79% and 2.01%, respectively. Furthermore, the 4'-methoxyquercetin flavanoid compound was isolated from the ethanolic fraction. The minimum inhibiting concentration in the antimicrobial test was 2.0 mg/ml for Staphylococcus aureus, and a DL50 of 0.231 mg/mL was obtained in the cytotoxicity experiment. The fraction directed to alkaloids was able to eliminate 100% of the brine shrimp used for the test.Sociedade Brasileira de Farmacognosia2011-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000100008Revista Brasileira de Farmacognosia v.21 n.1 2011reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2011005000005info:eu-repo/semantics/openAccessFerraz,Helena O.Silva,Magali G.Carvalho,RuiSuffredini,Ivana B.Kato,Edna T. M.Arakaki,FernandaBacchi,Elfriede M.eng2011-03-28T00:00:00Zoai:scielo:S0102-695X2011000100008Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2011-03-28T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa
title Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa
spellingShingle Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa
Ferraz,Helena O.
Cuscuta racemosa
Convolvulaceae
antimicrobial activity
cytotoxicity
title_short Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa
title_full Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa
title_fullStr Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa
title_full_unstemmed Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa
title_sort Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa
author Ferraz,Helena O.
author_facet Ferraz,Helena O.
Silva,Magali G.
Carvalho,Rui
Suffredini,Ivana B.
Kato,Edna T. M.
Arakaki,Fernanda
Bacchi,Elfriede M.
author_role author
author2 Silva,Magali G.
Carvalho,Rui
Suffredini,Ivana B.
Kato,Edna T. M.
Arakaki,Fernanda
Bacchi,Elfriede M.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Ferraz,Helena O.
Silva,Magali G.
Carvalho,Rui
Suffredini,Ivana B.
Kato,Edna T. M.
Arakaki,Fernanda
Bacchi,Elfriede M.
dc.subject.por.fl_str_mv Cuscuta racemosa
Convolvulaceae
antimicrobial activity
cytotoxicity
topic Cuscuta racemosa
Convolvulaceae
antimicrobial activity
cytotoxicity
description Cuscuta racemosa Mart. is a parasitic plant of the Convolvulaceae family, used in popular medicine as an anti-inflammatory and a diuretic, for stomach and hepatic disorders, and for treating fresh wounds. This plant is popularly known as "cipó-chumbo" and "fios-de-ovos". In this study, it was chemically investigated and tested for its antimicrobial activity and cytotoxicity. The flavonoid and tannin content of the dried plant were 2.79% and 2.01%, respectively. Furthermore, the 4'-methoxyquercetin flavanoid compound was isolated from the ethanolic fraction. The minimum inhibiting concentration in the antimicrobial test was 2.0 mg/ml for Staphylococcus aureus, and a DL50 of 0.231 mg/mL was obtained in the cytotoxicity experiment. The fraction directed to alkaloids was able to eliminate 100% of the brine shrimp used for the test.
publishDate 2011
dc.date.none.fl_str_mv 2011-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000100008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000100008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-695X2011005000005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.21 n.1 2011
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
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repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
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