Clastogenic activity of integerrimine determined in mouse micronucleus assays

Detalhes bibliográficos
Autor(a) principal: Gimmler-Luz,Maria Clara
Data de Publicação: 1997
Outros Autores: Erdtmann,Bernardo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Genetics
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-84551997000300008
Resumo: The pyrrolizidine alkaloid integerrimine, obtained from Senecio brasiliensis, was tested by acute dosing at two concentrations (18.75 and 37.5 mg/kg), and at different times, to establish its ability to induce micronuclei in mouse erythrocytes. This alkaloid was able to increase the frequency of micronucleated polychromatic erythrocytes in both, bone marrow and peripheral blood erythrocytes
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spelling Clastogenic activity of integerrimine determined in mouse micronucleus assaysThe pyrrolizidine alkaloid integerrimine, obtained from Senecio brasiliensis, was tested by acute dosing at two concentrations (18.75 and 37.5 mg/kg), and at different times, to establish its ability to induce micronuclei in mouse erythrocytes. This alkaloid was able to increase the frequency of micronucleated polychromatic erythrocytes in both, bone marrow and peripheral blood erythrocytesSociedade Brasileira de Genética1997-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-84551997000300008Brazilian Journal of Genetics v.20 n.3 1997reponame:Brazilian Journal of Geneticsinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/S0100-84551997000300008info:eu-repo/semantics/openAccessGimmler-Luz,Maria ClaraErdtmann,Bernardoeng1998-10-06T00:00:00Zoai:scielo:S0100-84551997000300008Revistahttps://www.gmb.org.br/brazilian-journal-of-geneticsONGhttps://old.scielo.br/oai/scielo-oai.phpsede@sgb.org.br || sede@sgb.org.br0100-84550100-8455opendoar:1998-10-06T00:00Brazilian Journal of Genetics - Sociedade Brasileira de Genética (SBG)false
dc.title.none.fl_str_mv Clastogenic activity of integerrimine determined in mouse micronucleus assays
title Clastogenic activity of integerrimine determined in mouse micronucleus assays
spellingShingle Clastogenic activity of integerrimine determined in mouse micronucleus assays
Gimmler-Luz,Maria Clara
title_short Clastogenic activity of integerrimine determined in mouse micronucleus assays
title_full Clastogenic activity of integerrimine determined in mouse micronucleus assays
title_fullStr Clastogenic activity of integerrimine determined in mouse micronucleus assays
title_full_unstemmed Clastogenic activity of integerrimine determined in mouse micronucleus assays
title_sort Clastogenic activity of integerrimine determined in mouse micronucleus assays
author Gimmler-Luz,Maria Clara
author_facet Gimmler-Luz,Maria Clara
Erdtmann,Bernardo
author_role author
author2 Erdtmann,Bernardo
author2_role author
dc.contributor.author.fl_str_mv Gimmler-Luz,Maria Clara
Erdtmann,Bernardo
description The pyrrolizidine alkaloid integerrimine, obtained from Senecio brasiliensis, was tested by acute dosing at two concentrations (18.75 and 37.5 mg/kg), and at different times, to establish its ability to induce micronuclei in mouse erythrocytes. This alkaloid was able to increase the frequency of micronucleated polychromatic erythrocytes in both, bone marrow and peripheral blood erythrocytes
publishDate 1997
dc.date.none.fl_str_mv 1997-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-84551997000300008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-84551997000300008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-84551997000300008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Genética
publisher.none.fl_str_mv Sociedade Brasileira de Genética
dc.source.none.fl_str_mv Brazilian Journal of Genetics v.20 n.3 1997
reponame:Brazilian Journal of Genetics
instname:Sociedade Brasileira de Genética (SBG)
instacron:SBG
instname_str Sociedade Brasileira de Genética (SBG)
instacron_str SBG
institution SBG
reponame_str Brazilian Journal of Genetics
collection Brazilian Journal of Genetics
repository.name.fl_str_mv Brazilian Journal of Genetics - Sociedade Brasileira de Genética (SBG)
repository.mail.fl_str_mv sede@sgb.org.br || sede@sgb.org.br
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