Epidemiology of oral HPV in the oral mucosa in women without signs of oral disease from Yucatan, Mexico
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Microbiology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000100301 |
Resumo: | High-risk human papillomaviruses (HR-HPV) are considered necessary for the development of cervical cancer. Furthermore, there is no doubt that some types of oral squamous cell carcinoma are associated with HR-HPV. The epidemiology of oral HPV infections in healthy subjects remains unclear due to a lack of knowledge. The objective of this study was to investigate the epidemiology of human papillomavirus infections of the oral mucosa without pathology. A cross-sectional study was performed; samples from 390 women seeking prenatal care, Pap smears, family planning or gynecological diseases were studied. Oral cells were collected by direct swab sampling. Information regarding sociodemographic status, sexual behavior, infectious diseases, contraceptive history and tobacco and alcohol consumption were obtained through direct interviews. HPV and genotypes were detected by type-specific polymerase chain reaction. Our results revealed that 14% of the women studied had an oral HPV infection. Women ≤ 20 years of age had the highest HPV prevalence (24.5%). In total, seven genotypes were identified, including the high-risk genotypes 16, 18, 58 and 59 and the low-risk genotypes 6, 81 and 13, the latter of which is a type exclusive to oral mucosa. Sexual behavior was not associated with the presence of genital HPV types in the oral mucosa. Genital HPV types were present in the oral mucosa of women without associated clinical manifestations; however, sexual behavior was not associated with infection, and therefore others routes of transmission should be explored. |
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Epidemiology of oral HPV in the oral mucosa in women without signs of oral disease from Yucatan, MexicoPapillomavirusoral mucosaHPV13MexicoHigh-risk human papillomaviruses (HR-HPV) are considered necessary for the development of cervical cancer. Furthermore, there is no doubt that some types of oral squamous cell carcinoma are associated with HR-HPV. The epidemiology of oral HPV infections in healthy subjects remains unclear due to a lack of knowledge. The objective of this study was to investigate the epidemiology of human papillomavirus infections of the oral mucosa without pathology. A cross-sectional study was performed; samples from 390 women seeking prenatal care, Pap smears, family planning or gynecological diseases were studied. Oral cells were collected by direct swab sampling. Information regarding sociodemographic status, sexual behavior, infectious diseases, contraceptive history and tobacco and alcohol consumption were obtained through direct interviews. HPV and genotypes were detected by type-specific polymerase chain reaction. Our results revealed that 14% of the women studied had an oral HPV infection. Women ≤ 20 years of age had the highest HPV prevalence (24.5%). In total, seven genotypes were identified, including the high-risk genotypes 16, 18, 58 and 59 and the low-risk genotypes 6, 81 and 13, the latter of which is a type exclusive to oral mucosa. Sexual behavior was not associated with the presence of genital HPV types in the oral mucosa. Genital HPV types were present in the oral mucosa of women without associated clinical manifestations; however, sexual behavior was not associated with infection, and therefore others routes of transmission should be explored.Sociedade Brasileira de Microbiologia2015-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000100301Brazilian Journal of Microbiology v.46 n.1 2015reponame:Brazilian Journal of Microbiologyinstname:Sociedade Brasileira de Microbiologia (SBM)instacron:SBM10.1590/S1517-838246120130976info:eu-repo/semantics/openAccessGonzalez-Losa,María del RefugioBarrera,Ernesto SoriaHerrera-Pech,VerónicaConde-Ferráez,LauraPuerto-Solís,MarylinAyora-Talavera,Guadalupeeng2015-10-27T00:00:00Zoai:scielo:S1517-83822015000100301Revistahttps://www.scielo.br/j/bjm/ONGhttps://old.scielo.br/oai/scielo-oai.phpbjm@sbmicrobiologia.org.br||mbmartin@usp.br1678-44051517-8382opendoar:2015-10-27T00:00Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM)false |
dc.title.none.fl_str_mv |
Epidemiology of oral HPV in the oral mucosa in women without signs of oral disease from Yucatan, Mexico |
title |
Epidemiology of oral HPV in the oral mucosa in women without signs of oral disease from Yucatan, Mexico |
spellingShingle |
Epidemiology of oral HPV in the oral mucosa in women without signs of oral disease from Yucatan, Mexico Gonzalez-Losa,María del Refugio Papillomavirus oral mucosa HPV13 Mexico |
title_short |
Epidemiology of oral HPV in the oral mucosa in women without signs of oral disease from Yucatan, Mexico |
title_full |
Epidemiology of oral HPV in the oral mucosa in women without signs of oral disease from Yucatan, Mexico |
title_fullStr |
Epidemiology of oral HPV in the oral mucosa in women without signs of oral disease from Yucatan, Mexico |
title_full_unstemmed |
Epidemiology of oral HPV in the oral mucosa in women without signs of oral disease from Yucatan, Mexico |
title_sort |
Epidemiology of oral HPV in the oral mucosa in women without signs of oral disease from Yucatan, Mexico |
author |
Gonzalez-Losa,María del Refugio |
author_facet |
Gonzalez-Losa,María del Refugio Barrera,Ernesto Soria Herrera-Pech,Verónica Conde-Ferráez,Laura Puerto-Solís,Marylin Ayora-Talavera,Guadalupe |
author_role |
author |
author2 |
Barrera,Ernesto Soria Herrera-Pech,Verónica Conde-Ferráez,Laura Puerto-Solís,Marylin Ayora-Talavera,Guadalupe |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Gonzalez-Losa,María del Refugio Barrera,Ernesto Soria Herrera-Pech,Verónica Conde-Ferráez,Laura Puerto-Solís,Marylin Ayora-Talavera,Guadalupe |
dc.subject.por.fl_str_mv |
Papillomavirus oral mucosa HPV13 Mexico |
topic |
Papillomavirus oral mucosa HPV13 Mexico |
description |
High-risk human papillomaviruses (HR-HPV) are considered necessary for the development of cervical cancer. Furthermore, there is no doubt that some types of oral squamous cell carcinoma are associated with HR-HPV. The epidemiology of oral HPV infections in healthy subjects remains unclear due to a lack of knowledge. The objective of this study was to investigate the epidemiology of human papillomavirus infections of the oral mucosa without pathology. A cross-sectional study was performed; samples from 390 women seeking prenatal care, Pap smears, family planning or gynecological diseases were studied. Oral cells were collected by direct swab sampling. Information regarding sociodemographic status, sexual behavior, infectious diseases, contraceptive history and tobacco and alcohol consumption were obtained through direct interviews. HPV and genotypes were detected by type-specific polymerase chain reaction. Our results revealed that 14% of the women studied had an oral HPV infection. Women ≤ 20 years of age had the highest HPV prevalence (24.5%). In total, seven genotypes were identified, including the high-risk genotypes 16, 18, 58 and 59 and the low-risk genotypes 6, 81 and 13, the latter of which is a type exclusive to oral mucosa. Sexual behavior was not associated with the presence of genital HPV types in the oral mucosa. Genital HPV types were present in the oral mucosa of women without associated clinical manifestations; however, sexual behavior was not associated with infection, and therefore others routes of transmission should be explored. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000100301 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000100301 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1517-838246120130976 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Microbiologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Microbiologia |
dc.source.none.fl_str_mv |
Brazilian Journal of Microbiology v.46 n.1 2015 reponame:Brazilian Journal of Microbiology instname:Sociedade Brasileira de Microbiologia (SBM) instacron:SBM |
instname_str |
Sociedade Brasileira de Microbiologia (SBM) |
instacron_str |
SBM |
institution |
SBM |
reponame_str |
Brazilian Journal of Microbiology |
collection |
Brazilian Journal of Microbiology |
repository.name.fl_str_mv |
Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM) |
repository.mail.fl_str_mv |
bjm@sbmicrobiologia.org.br||mbmartin@usp.br |
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1752122207420547072 |