Whole cells in enantioselective reduction of benzyl acetoacetate

Detalhes bibliográficos
Autor(a) principal: Ribeiro,Joyce Benzaquem
Data de Publicação: 2014
Outros Autores: Ramos,Aline de Souza, Lopes,Raquel de Oliveira, Silva,Gabriela Veloso Vieira da, Souza,Rodrigo Octavio Mendonça Alves de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Microbiology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000300023
Resumo: The β-ketoester benzyl acetoacetate was enantioselectively reduced to benzyl (S)-3-hydroxybutanoate by seven microorganism species. The best result using free cells was obtained with the yeast Hansenula sp., which furnished 97% ee and 85% of conversion within 24 h. After immobilization in calcium alginate spheres, K.marxianus showed to be more stable after 2 cycles of reaction.
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spelling Whole cells in enantioselective reduction of benzyl acetoacetatebiotransformationchiral reductionβ-ketoesterKluyveromyces marxianusimmobilizationThe β-ketoester benzyl acetoacetate was enantioselectively reduced to benzyl (S)-3-hydroxybutanoate by seven microorganism species. The best result using free cells was obtained with the yeast Hansenula sp., which furnished 97% ee and 85% of conversion within 24 h. After immobilization in calcium alginate spheres, K.marxianus showed to be more stable after 2 cycles of reaction.Sociedade Brasileira de Microbiologia2014-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000300023Brazilian Journal of Microbiology v.45 n.3 2014reponame:Brazilian Journal of Microbiologyinstname:Sociedade Brasileira de Microbiologia (SBM)instacron:SBM10.1590/S1517-83822014000300023info:eu-repo/semantics/openAccessRibeiro,Joyce BenzaquemRamos,Aline de SouzaLopes,Raquel de OliveiraSilva,Gabriela Veloso Vieira daSouza,Rodrigo Octavio Mendonça Alves deeng2014-11-04T00:00:00Zoai:scielo:S1517-83822014000300023Revistahttps://www.scielo.br/j/bjm/ONGhttps://old.scielo.br/oai/scielo-oai.phpbjm@sbmicrobiologia.org.br||mbmartin@usp.br1678-44051517-8382opendoar:2014-11-04T00:00Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM)false
dc.title.none.fl_str_mv Whole cells in enantioselective reduction of benzyl acetoacetate
title Whole cells in enantioselective reduction of benzyl acetoacetate
spellingShingle Whole cells in enantioselective reduction of benzyl acetoacetate
Ribeiro,Joyce Benzaquem
biotransformation
chiral reduction
β-ketoester
Kluyveromyces marxianus
immobilization
title_short Whole cells in enantioselective reduction of benzyl acetoacetate
title_full Whole cells in enantioselective reduction of benzyl acetoacetate
title_fullStr Whole cells in enantioselective reduction of benzyl acetoacetate
title_full_unstemmed Whole cells in enantioselective reduction of benzyl acetoacetate
title_sort Whole cells in enantioselective reduction of benzyl acetoacetate
author Ribeiro,Joyce Benzaquem
author_facet Ribeiro,Joyce Benzaquem
Ramos,Aline de Souza
Lopes,Raquel de Oliveira
Silva,Gabriela Veloso Vieira da
Souza,Rodrigo Octavio Mendonça Alves de
author_role author
author2 Ramos,Aline de Souza
Lopes,Raquel de Oliveira
Silva,Gabriela Veloso Vieira da
Souza,Rodrigo Octavio Mendonça Alves de
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Ribeiro,Joyce Benzaquem
Ramos,Aline de Souza
Lopes,Raquel de Oliveira
Silva,Gabriela Veloso Vieira da
Souza,Rodrigo Octavio Mendonça Alves de
dc.subject.por.fl_str_mv biotransformation
chiral reduction
β-ketoester
Kluyveromyces marxianus
immobilization
topic biotransformation
chiral reduction
β-ketoester
Kluyveromyces marxianus
immobilization
description The β-ketoester benzyl acetoacetate was enantioselectively reduced to benzyl (S)-3-hydroxybutanoate by seven microorganism species. The best result using free cells was obtained with the yeast Hansenula sp., which furnished 97% ee and 85% of conversion within 24 h. After immobilization in calcium alginate spheres, K.marxianus showed to be more stable after 2 cycles of reaction.
publishDate 2014
dc.date.none.fl_str_mv 2014-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000300023
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000300023
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1517-83822014000300023
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Microbiologia
publisher.none.fl_str_mv Sociedade Brasileira de Microbiologia
dc.source.none.fl_str_mv Brazilian Journal of Microbiology v.45 n.3 2014
reponame:Brazilian Journal of Microbiology
instname:Sociedade Brasileira de Microbiologia (SBM)
instacron:SBM
instname_str Sociedade Brasileira de Microbiologia (SBM)
instacron_str SBM
institution SBM
reponame_str Brazilian Journal of Microbiology
collection Brazilian Journal of Microbiology
repository.name.fl_str_mv Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM)
repository.mail.fl_str_mv bjm@sbmicrobiologia.org.br||mbmartin@usp.br
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