Recombination and Genetic Diversity

Detalhes bibliográficos
Autor(a) principal: Coutinho,T. C.
Data de Publicação: 2012
Outros Autores: Silva,T.T.da, Toledo,G.L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: TEMA (Sociedade Brasileira de Matemática Aplicada e Computacional. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2179-84512012000300007
Resumo: In this paper we present a spatial stochastic model for genetic recombination, that answers if diversity is preserved in an infinite population of recombinat-ing individuals distributed spatially. We show that, for finite times, recombination may maintain all the various potential different types, but when time grows infinitely, the diversity of individuals extinguishes off. So under the model premisses, recombination and spatial localization alone are not enough to explain diversity in a population. Further we discuss an application of the model to a controversy regarding the diversity of "Major Histocompatibility Complex" (MHC).
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spelling Recombination and Genetic DiversityGenetic recombinationspatial stochastic modelMajor Histocompatibility Complex (MHC)In this paper we present a spatial stochastic model for genetic recombination, that answers if diversity is preserved in an infinite population of recombinat-ing individuals distributed spatially. We show that, for finite times, recombination may maintain all the various potential different types, but when time grows infinitely, the diversity of individuals extinguishes off. So under the model premisses, recombination and spatial localization alone are not enough to explain diversity in a population. Further we discuss an application of the model to a controversy regarding the diversity of "Major Histocompatibility Complex" (MHC).Sociedade Brasileira de Matemática Aplicada e Computacional2012-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2179-84512012000300007TEMA (São Carlos) v.13 n.3 2012reponame:TEMA (Sociedade Brasileira de Matemática Aplicada e Computacional. Online)instname:Sociedade Brasileira de Matemática Aplicada e Computacionalinstacron:SBMAC10.5540/TEMA.2012.013.03.265info:eu-repo/semantics/openAccessCoutinho,T. C.Silva,T.T.daToledo,G.L.eng2013-01-16T00:00:00Zoai:scielo:S2179-84512012000300007Revistahttp://www.scielo.br/temaPUBhttps://old.scielo.br/oai/scielo-oai.phpcastelo@icmc.usp.br2179-84511677-1966opendoar:2013-01-16T00:00TEMA (Sociedade Brasileira de Matemática Aplicada e Computacional. Online) - Sociedade Brasileira de Matemática Aplicada e Computacionalfalse
dc.title.none.fl_str_mv Recombination and Genetic Diversity
title Recombination and Genetic Diversity
spellingShingle Recombination and Genetic Diversity
Coutinho,T. C.
Genetic recombination
spatial stochastic model
Major Histocompatibility Complex (MHC)
title_short Recombination and Genetic Diversity
title_full Recombination and Genetic Diversity
title_fullStr Recombination and Genetic Diversity
title_full_unstemmed Recombination and Genetic Diversity
title_sort Recombination and Genetic Diversity
author Coutinho,T. C.
author_facet Coutinho,T. C.
Silva,T.T.da
Toledo,G.L.
author_role author
author2 Silva,T.T.da
Toledo,G.L.
author2_role author
author
dc.contributor.author.fl_str_mv Coutinho,T. C.
Silva,T.T.da
Toledo,G.L.
dc.subject.por.fl_str_mv Genetic recombination
spatial stochastic model
Major Histocompatibility Complex (MHC)
topic Genetic recombination
spatial stochastic model
Major Histocompatibility Complex (MHC)
description In this paper we present a spatial stochastic model for genetic recombination, that answers if diversity is preserved in an infinite population of recombinat-ing individuals distributed spatially. We show that, for finite times, recombination may maintain all the various potential different types, but when time grows infinitely, the diversity of individuals extinguishes off. So under the model premisses, recombination and spatial localization alone are not enough to explain diversity in a population. Further we discuss an application of the model to a controversy regarding the diversity of "Major Histocompatibility Complex" (MHC).
publishDate 2012
dc.date.none.fl_str_mv 2012-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2179-84512012000300007
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2179-84512012000300007
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5540/TEMA.2012.013.03.265
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Matemática Aplicada e Computacional
publisher.none.fl_str_mv Sociedade Brasileira de Matemática Aplicada e Computacional
dc.source.none.fl_str_mv TEMA (São Carlos) v.13 n.3 2012
reponame:TEMA (Sociedade Brasileira de Matemática Aplicada e Computacional. Online)
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instname_str Sociedade Brasileira de Matemática Aplicada e Computacional
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reponame_str TEMA (Sociedade Brasileira de Matemática Aplicada e Computacional. Online)
collection TEMA (Sociedade Brasileira de Matemática Aplicada e Computacional. Online)
repository.name.fl_str_mv TEMA (Sociedade Brasileira de Matemática Aplicada e Computacional. Online) - Sociedade Brasileira de Matemática Aplicada e Computacional
repository.mail.fl_str_mv castelo@icmc.usp.br
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