Successful therapeutic response of resistant cases of mucocutaneous leishmaniasis to a very low dose of antimony

Detalhes bibliográficos
Autor(a) principal: Oliveira-Neto,Manoel Paes de
Data de Publicação: 2006
Outros Autores: Mattos,Marise da Silva
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Revista da Sociedade Brasileira de Medicina Tropical
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822006000400011
Resumo: Two mucocutaneous leishmaniasis cases resistant to therapy are reported here. After the failure of initial therapies (antimony, amphotericin B and/or pentamidine) patients received a low-dose schedule: one ampoule of meglumine antimoniate (405mg of pentavalent antimony [Sb v]) by intramuscular injection, three times a week until complete healing of the lesions. One patient was cured with a total of 30 ampoules in 10 weeks and the other received 36 ampoules in 12 weeks. Both remain clinically cured after one year of follow-up.
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spelling Successful therapeutic response of resistant cases of mucocutaneous leishmaniasis to a very low dose of antimonyMucocutaneous leishmaniasisTherapy-resistanceAntimonyLow doseTwo mucocutaneous leishmaniasis cases resistant to therapy are reported here. After the failure of initial therapies (antimony, amphotericin B and/or pentamidine) patients received a low-dose schedule: one ampoule of meglumine antimoniate (405mg of pentavalent antimony [Sb v]) by intramuscular injection, three times a week until complete healing of the lesions. One patient was cured with a total of 30 ampoules in 10 weeks and the other received 36 ampoules in 12 weeks. Both remain clinically cured after one year of follow-up.Sociedade Brasileira de Medicina Tropical - SBMT2006-08-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822006000400011Revista da Sociedade Brasileira de Medicina Tropical v.39 n.4 2006reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/S0037-86822006000400011info:eu-repo/semantics/openAccessOliveira-Neto,Manoel Paes deMattos,Marise da Silvaeng2006-09-25T00:00:00Zoai:scielo:S0037-86822006000400011Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2006-09-25T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false
dc.title.none.fl_str_mv Successful therapeutic response of resistant cases of mucocutaneous leishmaniasis to a very low dose of antimony
title Successful therapeutic response of resistant cases of mucocutaneous leishmaniasis to a very low dose of antimony
spellingShingle Successful therapeutic response of resistant cases of mucocutaneous leishmaniasis to a very low dose of antimony
Oliveira-Neto,Manoel Paes de
Mucocutaneous leishmaniasis
Therapy-resistance
Antimony
Low dose
title_short Successful therapeutic response of resistant cases of mucocutaneous leishmaniasis to a very low dose of antimony
title_full Successful therapeutic response of resistant cases of mucocutaneous leishmaniasis to a very low dose of antimony
title_fullStr Successful therapeutic response of resistant cases of mucocutaneous leishmaniasis to a very low dose of antimony
title_full_unstemmed Successful therapeutic response of resistant cases of mucocutaneous leishmaniasis to a very low dose of antimony
title_sort Successful therapeutic response of resistant cases of mucocutaneous leishmaniasis to a very low dose of antimony
author Oliveira-Neto,Manoel Paes de
author_facet Oliveira-Neto,Manoel Paes de
Mattos,Marise da Silva
author_role author
author2 Mattos,Marise da Silva
author2_role author
dc.contributor.author.fl_str_mv Oliveira-Neto,Manoel Paes de
Mattos,Marise da Silva
dc.subject.por.fl_str_mv Mucocutaneous leishmaniasis
Therapy-resistance
Antimony
Low dose
topic Mucocutaneous leishmaniasis
Therapy-resistance
Antimony
Low dose
description Two mucocutaneous leishmaniasis cases resistant to therapy are reported here. After the failure of initial therapies (antimony, amphotericin B and/or pentamidine) patients received a low-dose schedule: one ampoule of meglumine antimoniate (405mg of pentavalent antimony [Sb v]) by intramuscular injection, three times a week until complete healing of the lesions. One patient was cured with a total of 30 ampoules in 10 weeks and the other received 36 ampoules in 12 weeks. Both remain clinically cured after one year of follow-up.
publishDate 2006
dc.date.none.fl_str_mv 2006-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822006000400011
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822006000400011
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0037-86822006000400011
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
dc.source.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical v.39 n.4 2006
reponame:Revista da Sociedade Brasileira de Medicina Tropical
instname:Sociedade Brasileira de Medicina Tropical (SBMT)
instacron:SBMT
instname_str Sociedade Brasileira de Medicina Tropical (SBMT)
instacron_str SBMT
institution SBMT
reponame_str Revista da Sociedade Brasileira de Medicina Tropical
collection Revista da Sociedade Brasileira de Medicina Tropical
repository.name.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)
repository.mail.fl_str_mv ||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br
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