Immunotherapy, immunochemotherapy and chemotherapy for American cutaneous leishmaniasis treatment

Detalhes bibliográficos
Autor(a) principal: Mayrink,Wilson
Data de Publicação: 2006
Outros Autores: Botelho,Ana Cristina de Carvalho, Magalhães,Paulo Araújo, Batista,Sebastião Mariano, Lima,Antonio de Oliveira, Genaro,Odair, Costa,Carlos Alberto da, Melo,Maria Norma de, Michalick,Marilene Susan Marques, Williams,Paul, Dias,Magno, Caiaffa,Waleska Teixeira, Nascimento,Evaldo do, Machado-Coelho,George Luiz Lins
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista da Sociedade Brasileira de Medicina Tropical
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822006000100003
Resumo: The first choice of treatment for American cutaneous leishmaniasis is the pentavalent antimonial drug. Although it has been shown that this treatment is mostly effective and indicated, some disadvantages should be taken into account such as side effects, long term treatment inconveniences and counter-indication for patients suffering from cardiopathy, nephropathy; yet, aging, pregnancy and other conditions. With the advent of the vaccine anti-American cutaneous leishmaniasis as a prophylactic measure, studies on therapy using the vaccine associated or not with other drugs have been performed by many investigators and it is currently among the alternative treatments and prevention measures for American cutaneous leishmaniasis. In conclusion, the association between antimony and vaccine (immunochemotherapy) showed the same cure rate when compared with the standard treatment (100%) and it was also able to reduce the salt volume in 17.9% and treatment length from 87 to 62 days, decreasing side effects.
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spelling Immunotherapy, immunochemotherapy and chemotherapy for American cutaneous leishmaniasis treatmentAmerican cutaneous leishmaniasisTreatmentImmunotherapyThe first choice of treatment for American cutaneous leishmaniasis is the pentavalent antimonial drug. Although it has been shown that this treatment is mostly effective and indicated, some disadvantages should be taken into account such as side effects, long term treatment inconveniences and counter-indication for patients suffering from cardiopathy, nephropathy; yet, aging, pregnancy and other conditions. With the advent of the vaccine anti-American cutaneous leishmaniasis as a prophylactic measure, studies on therapy using the vaccine associated or not with other drugs have been performed by many investigators and it is currently among the alternative treatments and prevention measures for American cutaneous leishmaniasis. In conclusion, the association between antimony and vaccine (immunochemotherapy) showed the same cure rate when compared with the standard treatment (100%) and it was also able to reduce the salt volume in 17.9% and treatment length from 87 to 62 days, decreasing side effects.Sociedade Brasileira de Medicina Tropical - SBMT2006-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822006000100003Revista da Sociedade Brasileira de Medicina Tropical v.39 n.1 2006reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/S0037-86822006000100003info:eu-repo/semantics/openAccessMayrink,WilsonBotelho,Ana Cristina de CarvalhoMagalhães,Paulo AraújoBatista,Sebastião MarianoLima,Antonio de OliveiraGenaro,OdairCosta,Carlos Alberto daMelo,Maria Norma deMichalick,Marilene Susan MarquesWilliams,PaulDias,MagnoCaiaffa,Waleska TeixeiraNascimento,Evaldo doMachado-Coelho,George Luiz Linseng2006-02-23T00:00:00Zoai:scielo:S0037-86822006000100003Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2006-02-23T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false
dc.title.none.fl_str_mv Immunotherapy, immunochemotherapy and chemotherapy for American cutaneous leishmaniasis treatment
title Immunotherapy, immunochemotherapy and chemotherapy for American cutaneous leishmaniasis treatment
spellingShingle Immunotherapy, immunochemotherapy and chemotherapy for American cutaneous leishmaniasis treatment
Mayrink,Wilson
American cutaneous leishmaniasis
Treatment
Immunotherapy
title_short Immunotherapy, immunochemotherapy and chemotherapy for American cutaneous leishmaniasis treatment
title_full Immunotherapy, immunochemotherapy and chemotherapy for American cutaneous leishmaniasis treatment
title_fullStr Immunotherapy, immunochemotherapy and chemotherapy for American cutaneous leishmaniasis treatment
title_full_unstemmed Immunotherapy, immunochemotherapy and chemotherapy for American cutaneous leishmaniasis treatment
title_sort Immunotherapy, immunochemotherapy and chemotherapy for American cutaneous leishmaniasis treatment
author Mayrink,Wilson
author_facet Mayrink,Wilson
Botelho,Ana Cristina de Carvalho
Magalhães,Paulo Araújo
Batista,Sebastião Mariano
Lima,Antonio de Oliveira
Genaro,Odair
Costa,Carlos Alberto da
Melo,Maria Norma de
Michalick,Marilene Susan Marques
Williams,Paul
Dias,Magno
Caiaffa,Waleska Teixeira
Nascimento,Evaldo do
Machado-Coelho,George Luiz Lins
author_role author
author2 Botelho,Ana Cristina de Carvalho
Magalhães,Paulo Araújo
Batista,Sebastião Mariano
Lima,Antonio de Oliveira
Genaro,Odair
Costa,Carlos Alberto da
Melo,Maria Norma de
Michalick,Marilene Susan Marques
Williams,Paul
Dias,Magno
Caiaffa,Waleska Teixeira
Nascimento,Evaldo do
Machado-Coelho,George Luiz Lins
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Mayrink,Wilson
Botelho,Ana Cristina de Carvalho
Magalhães,Paulo Araújo
Batista,Sebastião Mariano
Lima,Antonio de Oliveira
Genaro,Odair
Costa,Carlos Alberto da
Melo,Maria Norma de
Michalick,Marilene Susan Marques
Williams,Paul
Dias,Magno
Caiaffa,Waleska Teixeira
Nascimento,Evaldo do
Machado-Coelho,George Luiz Lins
dc.subject.por.fl_str_mv American cutaneous leishmaniasis
Treatment
Immunotherapy
topic American cutaneous leishmaniasis
Treatment
Immunotherapy
description The first choice of treatment for American cutaneous leishmaniasis is the pentavalent antimonial drug. Although it has been shown that this treatment is mostly effective and indicated, some disadvantages should be taken into account such as side effects, long term treatment inconveniences and counter-indication for patients suffering from cardiopathy, nephropathy; yet, aging, pregnancy and other conditions. With the advent of the vaccine anti-American cutaneous leishmaniasis as a prophylactic measure, studies on therapy using the vaccine associated or not with other drugs have been performed by many investigators and it is currently among the alternative treatments and prevention measures for American cutaneous leishmaniasis. In conclusion, the association between antimony and vaccine (immunochemotherapy) showed the same cure rate when compared with the standard treatment (100%) and it was also able to reduce the salt volume in 17.9% and treatment length from 87 to 62 days, decreasing side effects.
publishDate 2006
dc.date.none.fl_str_mv 2006-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822006000100003
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822006000100003
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0037-86822006000100003
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
dc.source.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical v.39 n.1 2006
reponame:Revista da Sociedade Brasileira de Medicina Tropical
instname:Sociedade Brasileira de Medicina Tropical (SBMT)
instacron:SBMT
instname_str Sociedade Brasileira de Medicina Tropical (SBMT)
instacron_str SBMT
institution SBMT
reponame_str Revista da Sociedade Brasileira de Medicina Tropical
collection Revista da Sociedade Brasileira de Medicina Tropical
repository.name.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)
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