Severity of atopic dermatitis and Ascaris lumbricoides infection: an evaluation of CCR4+ and CXCR3+ helper T cell frequency

Detalhes bibliográficos
Autor(a) principal: Silva,Maria Teresa Nascimento
Data de Publicação: 2012
Outros Autores: Costa,Vlaudia Assis, Pereira,Teobaldo Gonzaga Realço, Sales,Iana Rafaela Fernandes, Silva,Silvana Ferreira da, Maciel,Maria Amélia Vieira, Malagueño,Elizabeth, Souza,Valdênia Maria Oliveira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista da Sociedade Brasileira de Medicina Tropical
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000600021
Resumo: INTRODUCTION: Ascaris lumbricoides-infected patients present lower prevalence of severe atopic dermatitis. METHODS: Peripheral blood of infected children with atopic dermatitis was assessed by flow cytometry of the frequency of Th1 and Th2 cells through the expression of CXCR3 and CCR4 chemokine receptors, respectively. RESULTS: Helminth-free patients with atopic dermatitis presented a high frequency of CCR4+Th2 cells. Parasitized patients with atopic dermatitis showed a lower frequency of CXCR3+Th1 cells compared to infected individuals only. CONCLUSIONS: Ascariasis modifies the blood traffic of Th2 cells in atopic dermatitis patients, while the allergic disease down-regulates the traffic of Th1 cells in parasitized patients.
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spelling Severity of atopic dermatitis and Ascaris lumbricoides infection: an evaluation of CCR4+ and CXCR3+ helper T cell frequencyAtopic dermatitisAscaris lumbricoidesCCR4 and CXCR3 receptorsINTRODUCTION: Ascaris lumbricoides-infected patients present lower prevalence of severe atopic dermatitis. METHODS: Peripheral blood of infected children with atopic dermatitis was assessed by flow cytometry of the frequency of Th1 and Th2 cells through the expression of CXCR3 and CCR4 chemokine receptors, respectively. RESULTS: Helminth-free patients with atopic dermatitis presented a high frequency of CCR4+Th2 cells. Parasitized patients with atopic dermatitis showed a lower frequency of CXCR3+Th1 cells compared to infected individuals only. CONCLUSIONS: Ascariasis modifies the blood traffic of Th2 cells in atopic dermatitis patients, while the allergic disease down-regulates the traffic of Th1 cells in parasitized patients.Sociedade Brasileira de Medicina Tropical - SBMT2012-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000600021Revista da Sociedade Brasileira de Medicina Tropical v.45 n.6 2012reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/S0037-86822012000600021info:eu-repo/semantics/openAccessSilva,Maria Teresa NascimentoCosta,Vlaudia AssisPereira,Teobaldo Gonzaga RealçoSales,Iana Rafaela FernandesSilva,Silvana Ferreira daMaciel,Maria Amélia VieiraMalagueño,ElizabethSouza,Valdênia Maria Oliveiraeng2013-01-04T00:00:00Zoai:scielo:S0037-86822012000600021Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2013-01-04T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false
dc.title.none.fl_str_mv Severity of atopic dermatitis and Ascaris lumbricoides infection: an evaluation of CCR4+ and CXCR3+ helper T cell frequency
title Severity of atopic dermatitis and Ascaris lumbricoides infection: an evaluation of CCR4+ and CXCR3+ helper T cell frequency
spellingShingle Severity of atopic dermatitis and Ascaris lumbricoides infection: an evaluation of CCR4+ and CXCR3+ helper T cell frequency
Silva,Maria Teresa Nascimento
Atopic dermatitis
Ascaris lumbricoides
CCR4 and CXCR3 receptors
title_short Severity of atopic dermatitis and Ascaris lumbricoides infection: an evaluation of CCR4+ and CXCR3+ helper T cell frequency
title_full Severity of atopic dermatitis and Ascaris lumbricoides infection: an evaluation of CCR4+ and CXCR3+ helper T cell frequency
title_fullStr Severity of atopic dermatitis and Ascaris lumbricoides infection: an evaluation of CCR4+ and CXCR3+ helper T cell frequency
title_full_unstemmed Severity of atopic dermatitis and Ascaris lumbricoides infection: an evaluation of CCR4+ and CXCR3+ helper T cell frequency
title_sort Severity of atopic dermatitis and Ascaris lumbricoides infection: an evaluation of CCR4+ and CXCR3+ helper T cell frequency
author Silva,Maria Teresa Nascimento
author_facet Silva,Maria Teresa Nascimento
Costa,Vlaudia Assis
Pereira,Teobaldo Gonzaga Realço
Sales,Iana Rafaela Fernandes
Silva,Silvana Ferreira da
Maciel,Maria Amélia Vieira
Malagueño,Elizabeth
Souza,Valdênia Maria Oliveira
author_role author
author2 Costa,Vlaudia Assis
Pereira,Teobaldo Gonzaga Realço
Sales,Iana Rafaela Fernandes
Silva,Silvana Ferreira da
Maciel,Maria Amélia Vieira
Malagueño,Elizabeth
Souza,Valdênia Maria Oliveira
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Silva,Maria Teresa Nascimento
Costa,Vlaudia Assis
Pereira,Teobaldo Gonzaga Realço
Sales,Iana Rafaela Fernandes
Silva,Silvana Ferreira da
Maciel,Maria Amélia Vieira
Malagueño,Elizabeth
Souza,Valdênia Maria Oliveira
dc.subject.por.fl_str_mv Atopic dermatitis
Ascaris lumbricoides
CCR4 and CXCR3 receptors
topic Atopic dermatitis
Ascaris lumbricoides
CCR4 and CXCR3 receptors
description INTRODUCTION: Ascaris lumbricoides-infected patients present lower prevalence of severe atopic dermatitis. METHODS: Peripheral blood of infected children with atopic dermatitis was assessed by flow cytometry of the frequency of Th1 and Th2 cells through the expression of CXCR3 and CCR4 chemokine receptors, respectively. RESULTS: Helminth-free patients with atopic dermatitis presented a high frequency of CCR4+Th2 cells. Parasitized patients with atopic dermatitis showed a lower frequency of CXCR3+Th1 cells compared to infected individuals only. CONCLUSIONS: Ascariasis modifies the blood traffic of Th2 cells in atopic dermatitis patients, while the allergic disease down-regulates the traffic of Th1 cells in parasitized patients.
publishDate 2012
dc.date.none.fl_str_mv 2012-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000600021
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000600021
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0037-86822012000600021
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
dc.source.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical v.45 n.6 2012
reponame:Revista da Sociedade Brasileira de Medicina Tropical
instname:Sociedade Brasileira de Medicina Tropical (SBMT)
instacron:SBMT
instname_str Sociedade Brasileira de Medicina Tropical (SBMT)
instacron_str SBMT
institution SBMT
reponame_str Revista da Sociedade Brasileira de Medicina Tropical
collection Revista da Sociedade Brasileira de Medicina Tropical
repository.name.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)
repository.mail.fl_str_mv ||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br
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