HISTOPATHOLOGICAL EVALUATION OF KIDNEYS, LIVER AND SPLEEN OF MICE UNDERGOING REPAIR OF SURGICAL WOUND IN THE ABDOMINAL WALL WITH BOVINE PERICARDIUM PRESERVED WITH GLYCERIN AND GLUTARALDEHYDE
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Brazilian Journal of Veterinary Medicine |
Texto Completo: | https://rbmv.org/BJVM/article/view/788 |
Resumo: | ABSTRACT. Martins C.R.P., Silva M.F.A., Nogueira V.A., Prado J.S & Brito M.F. [Histopathological evaluation of kidneys, liver and spleen of mice undergoing repair of surgical wound in the abdominal wall with bovine pericardium preserved with glycerin and glutaraldehyde]. Avaliação anatomopatológica de rins, fígado e baço de camundongos submetidos a implante de pericárdio bovino conservado em glicerina e glutaraldeído em ferida cirúrgica de parede abdominal. Revista Brasileira de Medicina Veterinária, 33(2):103-110, 2011. Curso de Pós-Graduação em Medicina Veterinária, BR-465 km 7, Universidade Federal Rural do Rio de Janeiro, Seropédica, 23890-000, Brasil. E-mail: carolinemedvet@yahoo.com.br The use of bovine pericardium as a biological membrane is widespread in surgical repair because of the low cost, good applicability and it is easily obtained. Glycerin 98% is the chemical agent most used as a biological tissue preservative in veterinary medicine, but studies have shown it is ineffective in eliminating viruses. Glutaraldehyde is a biological tissue preservative. However, the persistence of rabies virus in samples of mice pericardium preserved in 0.625% glutaraldehyde was proven, and probably higher concentrations are required for virucidal action. This study aims to evaluate macro-and microscopically kidney, liver and spleen of 65 mice, 60 of which underwent implantation of bovine pericardium preserved in glycerin 98% and 0.625%, 1% and 1.5% glutaraldehyde, and 5 mice served as controls. The implanted animals were assessed as to their macro and microscopic features of spleen, liver and kidneys. There were no macro or microscopic changes that could be related to the toxicity of these substances. |
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Brazilian Journal of Veterinary Medicine |
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HISTOPATHOLOGICAL EVALUATION OF KIDNEYS, LIVER AND SPLEEN OF MICE UNDERGOING REPAIR OF SURGICAL WOUND IN THE ABDOMINAL WALL WITH BOVINE PERICARDIUM PRESERVED WITH GLYCERIN AND GLUTARALDEHYDEAVALIAÇÃO ANATOMOPATOLÓGICA DE RINS, FÍGADO E BAÇO DE CAMUNDONGOS SUBMETIDOS A IMPLANTE DE PERICÁRDIO BOVINO CONSERVADO EM GLICERINA E GLUTARALDEÍDO EM FERIDA CIRÚRGICA DE PAREDE ABDOMINALBiopróteseglutaraldeídoglicerolBioprosthesisglutaralglycerolABSTRACT. Martins C.R.P., Silva M.F.A., Nogueira V.A., Prado J.S & Brito M.F. [Histopathological evaluation of kidneys, liver and spleen of mice undergoing repair of surgical wound in the abdominal wall with bovine pericardium preserved with glycerin and glutaraldehyde]. Avaliação anatomopatológica de rins, fígado e baço de camundongos submetidos a implante de pericárdio bovino conservado em glicerina e glutaraldeído em ferida cirúrgica de parede abdominal. Revista Brasileira de Medicina Veterinária, 33(2):103-110, 2011. Curso de Pós-Graduação em Medicina Veterinária, BR-465 km 7, Universidade Federal Rural do Rio de Janeiro, Seropédica, 23890-000, Brasil. E-mail: carolinemedvet@yahoo.com.br The use of bovine pericardium as a biological membrane is widespread in surgical repair because of the low cost, good applicability and it is easily obtained. Glycerin 98% is the chemical agent most used as a biological tissue preservative in veterinary medicine, but studies have shown it is ineffective in eliminating viruses. Glutaraldehyde is a biological tissue preservative. However, the persistence of rabies virus in samples of mice pericardium preserved in 0.625% glutaraldehyde was proven, and probably higher concentrations are required for virucidal action. This study aims to evaluate macro-and microscopically kidney, liver and spleen of 65 mice, 60 of which underwent implantation of bovine pericardium preserved in glycerin 98% and 0.625%, 1% and 1.5% glutaraldehyde, and 5 mice served as controls. The implanted animals were assessed as to their macro and microscopic features of spleen, liver and kidneys. There were no macro or microscopic changes that could be related to the toxicity of these substances.O emprego de pericárdio bovino como membrana biológica é bastante difundido em técnicas de reparos cirúrgicos devido à facilidade de aquisição, baixo custo e boa aplicabilidade. A glicerina 98% é o agente químico mais utilizado como conservante de tecidos biológicos em medicina veterinária, porém estudos comprovam sua ineficácia na eliminação viral. O glutaraldeído é um conservante de tecidos biológicos. Entretanto, a persistência do vírus rábico em amostras de pericárdio de camundongos conservadas em glutaraldeído 0,625% foi comprovada, sendo, provavelmente, necessárias concentrações mais altas para ação virucida. Este estudo teve como objetivo avaliar, macro e microscopicamente, rins, fígado e baço de 65 camundongos, dos quais 60 foram submetidos a implante de pericárdio bovino conservado em glicerina 98% e glutaraldeído a 0,625%, 1% e 1,5%; 5 camundongos serviram como controle. Não foram evidenciadas alterações macro ou microscópicas que pudessem estar relacionadas à toxicidade destas substâncias.Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.2011-06-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionpeer reviewedAvaliado pelos paresapplication/pdfhttps://rbmv.org/BJVM/article/view/788Brazilian Journal of Veterinary Medicine; Vol. 33 No. 2 (2011); 103-110Revista Brasileira de Medicina Veterinária; v. 33 n. 2 (2011); 103-1102527-21790100-2430reponame:Brazilian Journal of Veterinary Medicineinstname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)instacron:SBMVporhttps://rbmv.org/BJVM/article/view/788/644Martins, Caroline Rodrigues Pereirada Silva, Marta Fernanda AlbuquerqueNogueira, Vivian de AssunçãoPrado, Juliana da SilvaBrito, Marilene de Fariasinfo:eu-repo/semantics/openAccess2020-12-23T17:28:11Zoai:ojs.rbmv.org:article/788Revistahttps://rbmv.org/BJVMONGhttps://rbmv.org/BJVM/oaicontato.rbmv@gmail.com2527-21790100-2430opendoar:2020-12-23T17:28:11Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)false |
dc.title.none.fl_str_mv |
HISTOPATHOLOGICAL EVALUATION OF KIDNEYS, LIVER AND SPLEEN OF MICE UNDERGOING REPAIR OF SURGICAL WOUND IN THE ABDOMINAL WALL WITH BOVINE PERICARDIUM PRESERVED WITH GLYCERIN AND GLUTARALDEHYDE AVALIAÇÃO ANATOMOPATOLÓGICA DE RINS, FÍGADO E BAÇO DE CAMUNDONGOS SUBMETIDOS A IMPLANTE DE PERICÁRDIO BOVINO CONSERVADO EM GLICERINA E GLUTARALDEÍDO EM FERIDA CIRÚRGICA DE PAREDE ABDOMINAL |
title |
HISTOPATHOLOGICAL EVALUATION OF KIDNEYS, LIVER AND SPLEEN OF MICE UNDERGOING REPAIR OF SURGICAL WOUND IN THE ABDOMINAL WALL WITH BOVINE PERICARDIUM PRESERVED WITH GLYCERIN AND GLUTARALDEHYDE |
spellingShingle |
HISTOPATHOLOGICAL EVALUATION OF KIDNEYS, LIVER AND SPLEEN OF MICE UNDERGOING REPAIR OF SURGICAL WOUND IN THE ABDOMINAL WALL WITH BOVINE PERICARDIUM PRESERVED WITH GLYCERIN AND GLUTARALDEHYDE Martins, Caroline Rodrigues Pereira Bioprótese glutaraldeído glicerol Bioprosthesis glutaral glycerol |
title_short |
HISTOPATHOLOGICAL EVALUATION OF KIDNEYS, LIVER AND SPLEEN OF MICE UNDERGOING REPAIR OF SURGICAL WOUND IN THE ABDOMINAL WALL WITH BOVINE PERICARDIUM PRESERVED WITH GLYCERIN AND GLUTARALDEHYDE |
title_full |
HISTOPATHOLOGICAL EVALUATION OF KIDNEYS, LIVER AND SPLEEN OF MICE UNDERGOING REPAIR OF SURGICAL WOUND IN THE ABDOMINAL WALL WITH BOVINE PERICARDIUM PRESERVED WITH GLYCERIN AND GLUTARALDEHYDE |
title_fullStr |
HISTOPATHOLOGICAL EVALUATION OF KIDNEYS, LIVER AND SPLEEN OF MICE UNDERGOING REPAIR OF SURGICAL WOUND IN THE ABDOMINAL WALL WITH BOVINE PERICARDIUM PRESERVED WITH GLYCERIN AND GLUTARALDEHYDE |
title_full_unstemmed |
HISTOPATHOLOGICAL EVALUATION OF KIDNEYS, LIVER AND SPLEEN OF MICE UNDERGOING REPAIR OF SURGICAL WOUND IN THE ABDOMINAL WALL WITH BOVINE PERICARDIUM PRESERVED WITH GLYCERIN AND GLUTARALDEHYDE |
title_sort |
HISTOPATHOLOGICAL EVALUATION OF KIDNEYS, LIVER AND SPLEEN OF MICE UNDERGOING REPAIR OF SURGICAL WOUND IN THE ABDOMINAL WALL WITH BOVINE PERICARDIUM PRESERVED WITH GLYCERIN AND GLUTARALDEHYDE |
author |
Martins, Caroline Rodrigues Pereira |
author_facet |
Martins, Caroline Rodrigues Pereira da Silva, Marta Fernanda Albuquerque Nogueira, Vivian de Assunção Prado, Juliana da Silva Brito, Marilene de Farias |
author_role |
author |
author2 |
da Silva, Marta Fernanda Albuquerque Nogueira, Vivian de Assunção Prado, Juliana da Silva Brito, Marilene de Farias |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Martins, Caroline Rodrigues Pereira da Silva, Marta Fernanda Albuquerque Nogueira, Vivian de Assunção Prado, Juliana da Silva Brito, Marilene de Farias |
dc.subject.por.fl_str_mv |
Bioprótese glutaraldeído glicerol Bioprosthesis glutaral glycerol |
topic |
Bioprótese glutaraldeído glicerol Bioprosthesis glutaral glycerol |
description |
ABSTRACT. Martins C.R.P., Silva M.F.A., Nogueira V.A., Prado J.S & Brito M.F. [Histopathological evaluation of kidneys, liver and spleen of mice undergoing repair of surgical wound in the abdominal wall with bovine pericardium preserved with glycerin and glutaraldehyde]. Avaliação anatomopatológica de rins, fígado e baço de camundongos submetidos a implante de pericárdio bovino conservado em glicerina e glutaraldeído em ferida cirúrgica de parede abdominal. Revista Brasileira de Medicina Veterinária, 33(2):103-110, 2011. Curso de Pós-Graduação em Medicina Veterinária, BR-465 km 7, Universidade Federal Rural do Rio de Janeiro, Seropédica, 23890-000, Brasil. E-mail: carolinemedvet@yahoo.com.br The use of bovine pericardium as a biological membrane is widespread in surgical repair because of the low cost, good applicability and it is easily obtained. Glycerin 98% is the chemical agent most used as a biological tissue preservative in veterinary medicine, but studies have shown it is ineffective in eliminating viruses. Glutaraldehyde is a biological tissue preservative. However, the persistence of rabies virus in samples of mice pericardium preserved in 0.625% glutaraldehyde was proven, and probably higher concentrations are required for virucidal action. This study aims to evaluate macro-and microscopically kidney, liver and spleen of 65 mice, 60 of which underwent implantation of bovine pericardium preserved in glycerin 98% and 0.625%, 1% and 1.5% glutaraldehyde, and 5 mice served as controls. The implanted animals were assessed as to their macro and microscopic features of spleen, liver and kidneys. There were no macro or microscopic changes that could be related to the toxicity of these substances. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-06-30 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion peer reviewed Avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rbmv.org/BJVM/article/view/788 |
url |
https://rbmv.org/BJVM/article/view/788 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rbmv.org/BJVM/article/view/788/644 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade de Medicina Veterinária do Estado do Rio de Janeiro. |
publisher.none.fl_str_mv |
Sociedade de Medicina Veterinária do Estado do Rio de Janeiro. |
dc.source.none.fl_str_mv |
Brazilian Journal of Veterinary Medicine; Vol. 33 No. 2 (2011); 103-110 Revista Brasileira de Medicina Veterinária; v. 33 n. 2 (2011); 103-110 2527-2179 0100-2430 reponame:Brazilian Journal of Veterinary Medicine instname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ) instacron:SBMV |
instname_str |
Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ) |
instacron_str |
SBMV |
institution |
SBMV |
reponame_str |
Brazilian Journal of Veterinary Medicine |
collection |
Brazilian Journal of Veterinary Medicine |
repository.name.fl_str_mv |
Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ) |
repository.mail.fl_str_mv |
contato.rbmv@gmail.com |
_version_ |
1798313109533753344 |