Position statement from the Brazilian Society of Nephrology regarding chloroquine and hydroxychloroquine drug dose adjustment according to renal function

• Autor(a) principal: Moura-Neto,José A.
• Data de Publicação: 2020
• Outros Autores: Misael,Ana Maria, Silva,Dirceu Reis da, D’Avila,Ronaldo, Andreoli,Maria Claudia Cruz, Kraychete,Angiolina, Bastos,Kleyton, Nascimento,Marcelo Mazza do
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Jornal Brasileiro de Nefrologia
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002020000500049
• topic: Chloroquine; Hydroxychloroquine; Antimalarials; Posology; Drug Dosage Calculation; Renal Failure

ABSTRACT Chloroquine and hydroxychloroquine have shown promising preliminary results and have been discussed as therapeutic options for patients with Covid-19. Despite the lack of robust evidence demonstrating the benefits and justifying the use of one of these drugs, the final decision is the responsibility of the attending physician and should be individualized and shared, whenever possible. This position statement recommends dosage adjustment for these drugs in the context of renal impairment.