The influence of thalamosinusotomy under different constant intraocular pressures on aqueous outflow facility in isolated porcine eyes

Detalhes bibliográficos
Autor(a) principal: Mérula,Rafael Vidal
Data de Publicação: 2008
Outros Autores: Haefliger,Ivan O., Cronemberger,Sebastião, Calixto,Nassim
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Oftalmologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802008000100003
Resumo: PURPOSE: To explorethe effect of the thalamosinusotomy ab interno, which is an experimental surgical procedure similar to sclerothalamotomy ab interno, on aqueous humor drainage. METHODS: Enucleated porcine eyes were perfused with Krebs-Ringer's physiologic solution and trypan blue, in vitro, under different constant pressures after the experimental procedure.The outflow facility and the stained/unstained tissue were measured. RESULTS: The outflow facility and the area under the curve (outflow) increased with the increasing number of thalamosinusotomy incisions (0 to 4). Thalamosinusotomy eyes showed more stained tissue (conjunctiva, outer sclera, inner sclera) than sham surgery eyes with significant statistical difference (P<0.05). CONCLUSIONS: The results suggested that outflow facility increases with the increasing number of thalamus, different pathways are stimulated after thalamosinusotomy, and the uveoscleral outflow could be an important route after the experimental surgical procedure.
id SBO-1_cfd3c3073320205c87af3135df1cb24a
oai_identifier_str oai:scielo:S0034-72802008000100003
network_acronym_str SBO-1
network_name_str Revista Brasileira de Oftalmologia (Online)
repository_id_str
spelling The influence of thalamosinusotomy under different constant intraocular pressures on aqueous outflow facility in isolated porcine eyesThalamosinusotomySclerothalamotomyAqueous humorDrainage/methodsSwinePURPOSE: To explorethe effect of the thalamosinusotomy ab interno, which is an experimental surgical procedure similar to sclerothalamotomy ab interno, on aqueous humor drainage. METHODS: Enucleated porcine eyes were perfused with Krebs-Ringer's physiologic solution and trypan blue, in vitro, under different constant pressures after the experimental procedure.The outflow facility and the stained/unstained tissue were measured. RESULTS: The outflow facility and the area under the curve (outflow) increased with the increasing number of thalamosinusotomy incisions (0 to 4). Thalamosinusotomy eyes showed more stained tissue (conjunctiva, outer sclera, inner sclera) than sham surgery eyes with significant statistical difference (P<0.05). CONCLUSIONS: The results suggested that outflow facility increases with the increasing number of thalamus, different pathways are stimulated after thalamosinusotomy, and the uveoscleral outflow could be an important route after the experimental surgical procedure.Sociedade Brasileira de Oftalmologia2008-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802008000100003Revista Brasileira de Oftalmologia v.67 n.1 2008reponame:Revista Brasileira de Oftalmologia (Online)instname:Sociedade Brasileira de Oftalmologia (SBO)instacron:SBO10.1590/S0034-72802008000100003info:eu-repo/semantics/openAccessMérula,Rafael VidalHaefliger,Ivan O.Cronemberger,SebastiãoCalixto,Nassimeng2008-05-12T00:00:00Zoai:scielo:S0034-72802008000100003Revistahttps://rbo.emnuvens.com.br/rbo/indexhttps://old.scielo.br/oai/scielo-oai.phpsob@sboportal.org.br||rbo@sboportal.org.br1982-85510034-7280opendoar:2008-05-12T00:00Revista Brasileira de Oftalmologia (Online) - Sociedade Brasileira de Oftalmologia (SBO)false
dc.title.none.fl_str_mv The influence of thalamosinusotomy under different constant intraocular pressures on aqueous outflow facility in isolated porcine eyes
title The influence of thalamosinusotomy under different constant intraocular pressures on aqueous outflow facility in isolated porcine eyes
spellingShingle The influence of thalamosinusotomy under different constant intraocular pressures on aqueous outflow facility in isolated porcine eyes
Mérula,Rafael Vidal
Thalamosinusotomy
Sclerothalamotomy
Aqueous humor
Drainage/methods
Swine
title_short The influence of thalamosinusotomy under different constant intraocular pressures on aqueous outflow facility in isolated porcine eyes
title_full The influence of thalamosinusotomy under different constant intraocular pressures on aqueous outflow facility in isolated porcine eyes
title_fullStr The influence of thalamosinusotomy under different constant intraocular pressures on aqueous outflow facility in isolated porcine eyes
title_full_unstemmed The influence of thalamosinusotomy under different constant intraocular pressures on aqueous outflow facility in isolated porcine eyes
title_sort The influence of thalamosinusotomy under different constant intraocular pressures on aqueous outflow facility in isolated porcine eyes
author Mérula,Rafael Vidal
author_facet Mérula,Rafael Vidal
Haefliger,Ivan O.
Cronemberger,Sebastião
Calixto,Nassim
author_role author
author2 Haefliger,Ivan O.
Cronemberger,Sebastião
Calixto,Nassim
author2_role author
author
author
dc.contributor.author.fl_str_mv Mérula,Rafael Vidal
Haefliger,Ivan O.
Cronemberger,Sebastião
Calixto,Nassim
dc.subject.por.fl_str_mv Thalamosinusotomy
Sclerothalamotomy
Aqueous humor
Drainage/methods
Swine
topic Thalamosinusotomy
Sclerothalamotomy
Aqueous humor
Drainage/methods
Swine
description PURPOSE: To explorethe effect of the thalamosinusotomy ab interno, which is an experimental surgical procedure similar to sclerothalamotomy ab interno, on aqueous humor drainage. METHODS: Enucleated porcine eyes were perfused with Krebs-Ringer's physiologic solution and trypan blue, in vitro, under different constant pressures after the experimental procedure.The outflow facility and the stained/unstained tissue were measured. RESULTS: The outflow facility and the area under the curve (outflow) increased with the increasing number of thalamosinusotomy incisions (0 to 4). Thalamosinusotomy eyes showed more stained tissue (conjunctiva, outer sclera, inner sclera) than sham surgery eyes with significant statistical difference (P<0.05). CONCLUSIONS: The results suggested that outflow facility increases with the increasing number of thalamus, different pathways are stimulated after thalamosinusotomy, and the uveoscleral outflow could be an important route after the experimental surgical procedure.
publishDate 2008
dc.date.none.fl_str_mv 2008-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802008000100003
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802008000100003
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0034-72802008000100003
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Oftalmologia
publisher.none.fl_str_mv Sociedade Brasileira de Oftalmologia
dc.source.none.fl_str_mv Revista Brasileira de Oftalmologia v.67 n.1 2008
reponame:Revista Brasileira de Oftalmologia (Online)
instname:Sociedade Brasileira de Oftalmologia (SBO)
instacron:SBO
instname_str Sociedade Brasileira de Oftalmologia (SBO)
instacron_str SBO
institution SBO
reponame_str Revista Brasileira de Oftalmologia (Online)
collection Revista Brasileira de Oftalmologia (Online)
repository.name.fl_str_mv Revista Brasileira de Oftalmologia (Online) - Sociedade Brasileira de Oftalmologia (SBO)
repository.mail.fl_str_mv sob@sboportal.org.br||rbo@sboportal.org.br
_version_ 1752122335066849280

Registros relacionados