Vitamin D status and its relationship with bone mineral density in a healthy Iranian population

Detalhes bibliográficos
Autor(a) principal: Khashayar,Patricia
Data de Publicação: 2016
Outros Autores: Meybodi,Hamid Reza Aghaei, Hemami,Mohsen Rezai, Keshtkar,Abbasali, Dimai,Hans Peter, Larijani,Bagher
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Ortopedia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162016000400454
Resumo: ABSTRACT OBJECTIVES: Considering the controversial results regarding the relationship between vitamin D levels and bone mineral density in different populations, the present study was designed to evaluate this correlation in a healthy Iranian population. METHODS: Using a random cluster sample of apparently healthy men and women, this multicenter cross-sectional study was carried out among 4450 individuals living in urban areas of five major cities in Iran. Bone mineral density (BMD) values at different sites were analyzed along with the serum levels of 25(OH)D and PTH. Analysis of variance (ANOVA) was used to estimate the main effects, through comparing the mean values of these markers based on the bone mineral density status of the study group in each sex. RESULTS: 25(OH)D levels were inversely correlated with BMD values at total hip (r = -0.062 in men and r = -0.057 in women) and spine (r = -0.076 in men and r = -0.107 in women). After adjusting the data for age, the inverse correlation was no longer statistically significant. CONCLUSION: Serum 25(OH)D levels are inversely correlated with bone mass values in both sexes.
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spelling Vitamin D status and its relationship with bone mineral density in a healthy Iranian populationBone mineral densityOsteoporosisBiological markersVitamin DPhosphorusCalciumABSTRACT OBJECTIVES: Considering the controversial results regarding the relationship between vitamin D levels and bone mineral density in different populations, the present study was designed to evaluate this correlation in a healthy Iranian population. METHODS: Using a random cluster sample of apparently healthy men and women, this multicenter cross-sectional study was carried out among 4450 individuals living in urban areas of five major cities in Iran. Bone mineral density (BMD) values at different sites were analyzed along with the serum levels of 25(OH)D and PTH. Analysis of variance (ANOVA) was used to estimate the main effects, through comparing the mean values of these markers based on the bone mineral density status of the study group in each sex. RESULTS: 25(OH)D levels were inversely correlated with BMD values at total hip (r = -0.062 in men and r = -0.057 in women) and spine (r = -0.076 in men and r = -0.107 in women). After adjusting the data for age, the inverse correlation was no longer statistically significant. CONCLUSION: Serum 25(OH)D levels are inversely correlated with bone mass values in both sexes.Sociedade Brasileira de Ortopedia e Traumatologia2016-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162016000400454Revista Brasileira de Ortopedia v.51 n.4 2016reponame:Revista Brasileira de Ortopedia (Online)instname:Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)instacron:SBOT10.1016/j.rboe.2015.09.011info:eu-repo/semantics/openAccessKhashayar,PatriciaMeybodi,Hamid Reza AghaeiHemami,Mohsen RezaiKeshtkar,AbbasaliDimai,Hans PeterLarijani,Baghereng2016-08-23T00:00:00Zoai:scielo:S0102-36162016000400454Revistahttp://www.rbo.org.br/https://old.scielo.br/oai/scielo-oai.php||rbo@sbot.org.br1982-43780102-3616opendoar:2016-08-23T00:00Revista Brasileira de Ortopedia (Online) - Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)false
dc.title.none.fl_str_mv Vitamin D status and its relationship with bone mineral density in a healthy Iranian population
title Vitamin D status and its relationship with bone mineral density in a healthy Iranian population
spellingShingle Vitamin D status and its relationship with bone mineral density in a healthy Iranian population
Khashayar,Patricia
Bone mineral density
Osteoporosis
Biological markers
Vitamin D
Phosphorus
Calcium
title_short Vitamin D status and its relationship with bone mineral density in a healthy Iranian population
title_full Vitamin D status and its relationship with bone mineral density in a healthy Iranian population
title_fullStr Vitamin D status and its relationship with bone mineral density in a healthy Iranian population
title_full_unstemmed Vitamin D status and its relationship with bone mineral density in a healthy Iranian population
title_sort Vitamin D status and its relationship with bone mineral density in a healthy Iranian population
author Khashayar,Patricia
author_facet Khashayar,Patricia
Meybodi,Hamid Reza Aghaei
Hemami,Mohsen Rezai
Keshtkar,Abbasali
Dimai,Hans Peter
Larijani,Bagher
author_role author
author2 Meybodi,Hamid Reza Aghaei
Hemami,Mohsen Rezai
Keshtkar,Abbasali
Dimai,Hans Peter
Larijani,Bagher
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Khashayar,Patricia
Meybodi,Hamid Reza Aghaei
Hemami,Mohsen Rezai
Keshtkar,Abbasali
Dimai,Hans Peter
Larijani,Bagher
dc.subject.por.fl_str_mv Bone mineral density
Osteoporosis
Biological markers
Vitamin D
Phosphorus
Calcium
topic Bone mineral density
Osteoporosis
Biological markers
Vitamin D
Phosphorus
Calcium
description ABSTRACT OBJECTIVES: Considering the controversial results regarding the relationship between vitamin D levels and bone mineral density in different populations, the present study was designed to evaluate this correlation in a healthy Iranian population. METHODS: Using a random cluster sample of apparently healthy men and women, this multicenter cross-sectional study was carried out among 4450 individuals living in urban areas of five major cities in Iran. Bone mineral density (BMD) values at different sites were analyzed along with the serum levels of 25(OH)D and PTH. Analysis of variance (ANOVA) was used to estimate the main effects, through comparing the mean values of these markers based on the bone mineral density status of the study group in each sex. RESULTS: 25(OH)D levels were inversely correlated with BMD values at total hip (r = -0.062 in men and r = -0.057 in women) and spine (r = -0.076 in men and r = -0.107 in women). After adjusting the data for age, the inverse correlation was no longer statistically significant. CONCLUSION: Serum 25(OH)D levels are inversely correlated with bone mass values in both sexes.
publishDate 2016
dc.date.none.fl_str_mv 2016-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162016000400454
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162016000400454
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.rboe.2015.09.011
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Ortopedia e Traumatologia
publisher.none.fl_str_mv Sociedade Brasileira de Ortopedia e Traumatologia
dc.source.none.fl_str_mv Revista Brasileira de Ortopedia v.51 n.4 2016
reponame:Revista Brasileira de Ortopedia (Online)
instname:Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)
instacron:SBOT
instname_str Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)
instacron_str SBOT
institution SBOT
reponame_str Revista Brasileira de Ortopedia (Online)
collection Revista Brasileira de Ortopedia (Online)
repository.name.fl_str_mv Revista Brasileira de Ortopedia (Online) - Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)
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