Comparative study between immunoturbidimetric and latex agglutination methods for the detection of rheumatoid factor
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Jornal Brasileiro de Patologia e Medicina Laboratorial (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442013000100002 |
Resumo: | INTRODUCTION: The rheumatoid factor (RF) is the most common antibody found in patients with rheumatoid arthritis. It is an inflammatory chronic disease characterized by articular involvement, inflammation of synovial fluid, tissue infiltration by leucocytes and joint destruction, which ultimately determine articular deformities. The rheumatoid factor is found in 70%-80% of the adult population and in 10% of the young population. OBJECTIVE: The aim of this research was to compare immunoturbidimetric and latex agglutination methods for the detection of RF in serum. RESULTS: The immunoturbidimetric method displayed sensitivity (95.2%), specificity (89.4%) and high positive correlation (R² = 0,8077) with the latex agglutination method in positive serum samples. CONCLUSION: The study allowed to demonstrate that both immunoturbidimetric and latex agglutination methods equally discriminate between negative and positive serum samples for RF. |
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Comparative study between immunoturbidimetric and latex agglutination methods for the detection of rheumatoid factorrheumatoid factorlatex agglutination testimmunoturbidimetric methodINTRODUCTION: The rheumatoid factor (RF) is the most common antibody found in patients with rheumatoid arthritis. It is an inflammatory chronic disease characterized by articular involvement, inflammation of synovial fluid, tissue infiltration by leucocytes and joint destruction, which ultimately determine articular deformities. The rheumatoid factor is found in 70%-80% of the adult population and in 10% of the young population. OBJECTIVE: The aim of this research was to compare immunoturbidimetric and latex agglutination methods for the detection of RF in serum. RESULTS: The immunoturbidimetric method displayed sensitivity (95.2%), specificity (89.4%) and high positive correlation (R² = 0,8077) with the latex agglutination method in positive serum samples. CONCLUSION: The study allowed to demonstrate that both immunoturbidimetric and latex agglutination methods equally discriminate between negative and positive serum samples for RF.Sociedade Brasileira de Patologia Clínica2013-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442013000100002Jornal Brasileiro de Patologia e Medicina Laboratorial v.49 n.1 2013reponame:Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)instname:Sociedade Brasileira de Patologia (SBP)instacron:SBP10.1590/S1676-24442013000100002info:eu-repo/semantics/openAccessRocha,Katya CristinaBrinque,Luiz Alberto da FonsecaOliveira,Claudia G. B.Sant'Anna,Aleksandra Vanessa LambiasiFonseca,Alexandre Luiz AffonsoAzzalis,Ligia AjaimePereira,Edimar CristianoJunqueira,Virginia Berlanga CamposBeltrame,Registila LibaniaFonseca,Fernando Luiz Affonsoeng2013-05-20T00:00:00Zoai:scielo:S1676-24442013000100002Revistahttp://www.scielo.br/jbpmlhttps://old.scielo.br/oai/scielo-oai.php||jbpml@sbpc.org.br1678-47741676-2444opendoar:2013-05-20T00:00Jornal Brasileiro de Patologia e Medicina Laboratorial (Online) - Sociedade Brasileira de Patologia (SBP)false |
dc.title.none.fl_str_mv |
Comparative study between immunoturbidimetric and latex agglutination methods for the detection of rheumatoid factor |
title |
Comparative study between immunoturbidimetric and latex agglutination methods for the detection of rheumatoid factor |
spellingShingle |
Comparative study between immunoturbidimetric and latex agglutination methods for the detection of rheumatoid factor Rocha,Katya Cristina rheumatoid factor latex agglutination test immunoturbidimetric method |
title_short |
Comparative study between immunoturbidimetric and latex agglutination methods for the detection of rheumatoid factor |
title_full |
Comparative study between immunoturbidimetric and latex agglutination methods for the detection of rheumatoid factor |
title_fullStr |
Comparative study between immunoturbidimetric and latex agglutination methods for the detection of rheumatoid factor |
title_full_unstemmed |
Comparative study between immunoturbidimetric and latex agglutination methods for the detection of rheumatoid factor |
title_sort |
Comparative study between immunoturbidimetric and latex agglutination methods for the detection of rheumatoid factor |
author |
Rocha,Katya Cristina |
author_facet |
Rocha,Katya Cristina Brinque,Luiz Alberto da Fonseca Oliveira,Claudia G. B. Sant'Anna,Aleksandra Vanessa Lambiasi Fonseca,Alexandre Luiz Affonso Azzalis,Ligia Ajaime Pereira,Edimar Cristiano Junqueira,Virginia Berlanga Campos Beltrame,Registila Libania Fonseca,Fernando Luiz Affonso |
author_role |
author |
author2 |
Brinque,Luiz Alberto da Fonseca Oliveira,Claudia G. B. Sant'Anna,Aleksandra Vanessa Lambiasi Fonseca,Alexandre Luiz Affonso Azzalis,Ligia Ajaime Pereira,Edimar Cristiano Junqueira,Virginia Berlanga Campos Beltrame,Registila Libania Fonseca,Fernando Luiz Affonso |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Rocha,Katya Cristina Brinque,Luiz Alberto da Fonseca Oliveira,Claudia G. B. Sant'Anna,Aleksandra Vanessa Lambiasi Fonseca,Alexandre Luiz Affonso Azzalis,Ligia Ajaime Pereira,Edimar Cristiano Junqueira,Virginia Berlanga Campos Beltrame,Registila Libania Fonseca,Fernando Luiz Affonso |
dc.subject.por.fl_str_mv |
rheumatoid factor latex agglutination test immunoturbidimetric method |
topic |
rheumatoid factor latex agglutination test immunoturbidimetric method |
description |
INTRODUCTION: The rheumatoid factor (RF) is the most common antibody found in patients with rheumatoid arthritis. It is an inflammatory chronic disease characterized by articular involvement, inflammation of synovial fluid, tissue infiltration by leucocytes and joint destruction, which ultimately determine articular deformities. The rheumatoid factor is found in 70%-80% of the adult population and in 10% of the young population. OBJECTIVE: The aim of this research was to compare immunoturbidimetric and latex agglutination methods for the detection of RF in serum. RESULTS: The immunoturbidimetric method displayed sensitivity (95.2%), specificity (89.4%) and high positive correlation (R² = 0,8077) with the latex agglutination method in positive serum samples. CONCLUSION: The study allowed to demonstrate that both immunoturbidimetric and latex agglutination methods equally discriminate between negative and positive serum samples for RF. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442013000100002 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442013000100002 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1676-24442013000100002 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Patologia Clínica |
publisher.none.fl_str_mv |
Sociedade Brasileira de Patologia Clínica |
dc.source.none.fl_str_mv |
Jornal Brasileiro de Patologia e Medicina Laboratorial v.49 n.1 2013 reponame:Jornal Brasileiro de Patologia e Medicina Laboratorial (Online) instname:Sociedade Brasileira de Patologia (SBP) instacron:SBP |
instname_str |
Sociedade Brasileira de Patologia (SBP) |
instacron_str |
SBP |
institution |
SBP |
reponame_str |
Jornal Brasileiro de Patologia e Medicina Laboratorial (Online) |
collection |
Jornal Brasileiro de Patologia e Medicina Laboratorial (Online) |
repository.name.fl_str_mv |
Jornal Brasileiro de Patologia e Medicina Laboratorial (Online) - Sociedade Brasileira de Patologia (SBP) |
repository.mail.fl_str_mv |
||jbpml@sbpc.org.br |
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1752122295802920960 |