Etiologic role of root canal infection in apical periodontitis and its relationship with clinical symptomatology

Detalhes bibliográficos
Autor(a) principal: Gomes,Brenda Paula Figueiredo de Almeida
Data de Publicação: 2018
Outros Autores: Herrera,Daniel Rodrigo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Oral Research
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242018000500604
Resumo: Abstract: Evidence shows the polymicrobial etiology of endodontic infections, in which bacteria and their products are the main agents for the development, progression, and dissemination of apical periodontitis. Microbial factors in necrotic root canals (e.g., endotoxin) may spread into apical tissue, evoking and supporting a chronic inflammatory load. Thus, apical periodontitis is the result of the complex interplay between microbial factors and host defense against invasion of periradicular tissues. This review of the literature aims to discuss the complex network between endodontic infectious content and host immune response in apical periodontitis. A better understanding of the relationship of microbial factors with clinical symptomatology is important to establish appropriate therapeutic procedures for a more predictable outcome of endodontic treatment.
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spelling Etiologic role of root canal infection in apical periodontitis and its relationship with clinical symptomatologyPeriapical PeriodontitisPeriapical DiseasesLipopolysaccharidesCytokinesMatrix MetalloproteinasesAbstract: Evidence shows the polymicrobial etiology of endodontic infections, in which bacteria and their products are the main agents for the development, progression, and dissemination of apical periodontitis. Microbial factors in necrotic root canals (e.g., endotoxin) may spread into apical tissue, evoking and supporting a chronic inflammatory load. Thus, apical periodontitis is the result of the complex interplay between microbial factors and host defense against invasion of periradicular tissues. This review of the literature aims to discuss the complex network between endodontic infectious content and host immune response in apical periodontitis. A better understanding of the relationship of microbial factors with clinical symptomatology is important to establish appropriate therapeutic procedures for a more predictable outcome of endodontic treatment.Sociedade Brasileira de Pesquisa Odontológica - SBPqO2018-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242018000500604Brazilian Oral Research v.32 suppl.1 2018reponame:Brazilian Oral Researchinstname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)instacron:SBPQO10.1590/1807-3107bor-2018.vol32.0069info:eu-repo/semantics/openAccessGomes,Brenda Paula Figueiredo de AlmeidaHerrera,Daniel Rodrigoeng2018-10-10T00:00:00Zoai:scielo:S1806-83242018000500604Revistahttps://www.scielo.br/j/bor/https://old.scielo.br/oai/scielo-oai.phppob@edu.usp.br||bor@sbpqo.org.br1807-31071806-8324opendoar:2018-10-10T00:00Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)false
dc.title.none.fl_str_mv Etiologic role of root canal infection in apical periodontitis and its relationship with clinical symptomatology
title Etiologic role of root canal infection in apical periodontitis and its relationship with clinical symptomatology
spellingShingle Etiologic role of root canal infection in apical periodontitis and its relationship with clinical symptomatology
Gomes,Brenda Paula Figueiredo de Almeida
Periapical Periodontitis
Periapical Diseases
Lipopolysaccharides
Cytokines
Matrix Metalloproteinases
title_short Etiologic role of root canal infection in apical periodontitis and its relationship with clinical symptomatology
title_full Etiologic role of root canal infection in apical periodontitis and its relationship with clinical symptomatology
title_fullStr Etiologic role of root canal infection in apical periodontitis and its relationship with clinical symptomatology
title_full_unstemmed Etiologic role of root canal infection in apical periodontitis and its relationship with clinical symptomatology
title_sort Etiologic role of root canal infection in apical periodontitis and its relationship with clinical symptomatology
author Gomes,Brenda Paula Figueiredo de Almeida
author_facet Gomes,Brenda Paula Figueiredo de Almeida
Herrera,Daniel Rodrigo
author_role author
author2 Herrera,Daniel Rodrigo
author2_role author
dc.contributor.author.fl_str_mv Gomes,Brenda Paula Figueiredo de Almeida
Herrera,Daniel Rodrigo
dc.subject.por.fl_str_mv Periapical Periodontitis
Periapical Diseases
Lipopolysaccharides
Cytokines
Matrix Metalloproteinases
topic Periapical Periodontitis
Periapical Diseases
Lipopolysaccharides
Cytokines
Matrix Metalloproteinases
description Abstract: Evidence shows the polymicrobial etiology of endodontic infections, in which bacteria and their products are the main agents for the development, progression, and dissemination of apical periodontitis. Microbial factors in necrotic root canals (e.g., endotoxin) may spread into apical tissue, evoking and supporting a chronic inflammatory load. Thus, apical periodontitis is the result of the complex interplay between microbial factors and host defense against invasion of periradicular tissues. This review of the literature aims to discuss the complex network between endodontic infectious content and host immune response in apical periodontitis. A better understanding of the relationship of microbial factors with clinical symptomatology is important to establish appropriate therapeutic procedures for a more predictable outcome of endodontic treatment.
publishDate 2018
dc.date.none.fl_str_mv 2018-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242018000500604
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242018000500604
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1807-3107bor-2018.vol32.0069
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Pesquisa Odontológica - SBPqO
publisher.none.fl_str_mv Sociedade Brasileira de Pesquisa Odontológica - SBPqO
dc.source.none.fl_str_mv Brazilian Oral Research v.32 suppl.1 2018
reponame:Brazilian Oral Research
instname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron:SBPQO
instname_str Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron_str SBPQO
institution SBPQO
reponame_str Brazilian Oral Research
collection Brazilian Oral Research
repository.name.fl_str_mv Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
repository.mail.fl_str_mv pob@edu.usp.br||bor@sbpqo.org.br
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