Natural Product-Derived Drugs Based on β-Adrenergic Agents and Nucleosides

Detalhes bibliográficos
Autor(a) principal: Newman,David J.
Data de Publicação: 2016
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532016000801320
Resumo: This relatively short review demonstrates the very important role of the structures of the natural products adrenaline and relatives, in the design and subsequent approval of β-agonists and antagonists, and of modified nucleosides as anticancer, and in particular, antiviral agents against herpes (HSV), human immunodeficiency virus (HIV) and hepatitis C virus (HCV) that would not have been synthesized in the absence of knowledge of bioactive arabinose nucleosides.
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spelling Natural Product-Derived Drugs Based on β-Adrenergic Agents and Nucleosidesβ-agonistβ-antagonistnucleosidenatural product-based drugThis relatively short review demonstrates the very important role of the structures of the natural products adrenaline and relatives, in the design and subsequent approval of β-agonists and antagonists, and of modified nucleosides as anticancer, and in particular, antiviral agents against herpes (HSV), human immunodeficiency virus (HIV) and hepatitis C virus (HCV) that would not have been synthesized in the absence of knowledge of bioactive arabinose nucleosides.Sociedade Brasileira de Química2016-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532016000801320Journal of the Brazilian Chemical Society v.27 n.8 2016reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.5935/0103-5053.20160070info:eu-repo/semantics/openAccessNewman,David J.eng2016-08-19T00:00:00Zoai:scielo:S0103-50532016000801320Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2016-08-19T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Natural Product-Derived Drugs Based on β-Adrenergic Agents and Nucleosides
title Natural Product-Derived Drugs Based on β-Adrenergic Agents and Nucleosides
spellingShingle Natural Product-Derived Drugs Based on β-Adrenergic Agents and Nucleosides
Newman,David J.
β-agonist
β-antagonist
nucleoside
natural product-based drug
title_short Natural Product-Derived Drugs Based on β-Adrenergic Agents and Nucleosides
title_full Natural Product-Derived Drugs Based on β-Adrenergic Agents and Nucleosides
title_fullStr Natural Product-Derived Drugs Based on β-Adrenergic Agents and Nucleosides
title_full_unstemmed Natural Product-Derived Drugs Based on β-Adrenergic Agents and Nucleosides
title_sort Natural Product-Derived Drugs Based on β-Adrenergic Agents and Nucleosides
author Newman,David J.
author_facet Newman,David J.
author_role author
dc.contributor.author.fl_str_mv Newman,David J.
dc.subject.por.fl_str_mv β-agonist
β-antagonist
nucleoside
natural product-based drug
topic β-agonist
β-antagonist
nucleoside
natural product-based drug
description This relatively short review demonstrates the very important role of the structures of the natural products adrenaline and relatives, in the design and subsequent approval of β-agonists and antagonists, and of modified nucleosides as anticancer, and in particular, antiviral agents against herpes (HSV), human immunodeficiency virus (HIV) and hepatitis C virus (HCV) that would not have been synthesized in the absence of knowledge of bioactive arabinose nucleosides.
publishDate 2016
dc.date.none.fl_str_mv 2016-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532016000801320
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532016000801320
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0103-5053.20160070
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.27 n.8 2016
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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