A fast fluorimetric flow injection method to determine ibuprofen

Detalhes bibliográficos
Autor(a) principal: Lista,Adriana G.
Data de Publicação: 2006
Outros Autores: Palomeque,Miriam E., Band,Beatriz S. Fernández
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532006000700033
Resumo: The native fluorescence of ibuprofen was enhanced when a host-guest complex of the analyte with beta cyclodextrin (beta-CD) was formed. So, based on this fact, a flow injection method to determine ibuprofen in different pharmaceutical preparations with fluorescence detection (lambdaem 287 nm, lambdaexc 223 nm) was developed. The calibration curve was linear over the range 6.00 - 60.0 mg L-1 of ibuprofen and the detection limit (LOD) for S/N=3 was 4.5 mg L-1. The relative standard deviation was 1.2% and the sample throughput 240 h-1. The method was validated by comparing the proposed and the official method to commercial preparation samples.
id SBQ-2_4e642a2efa73e08f5f31b989a98d8226
oai_identifier_str oai:scielo:S0103-50532006000700033
network_acronym_str SBQ-2
network_name_str Journal of the Brazilian Chemical Society (Online)
repository_id_str
spelling A fast fluorimetric flow injection method to determine ibuprofenibuprofenFIAspectrofluorimetrypharmaceutical preparationThe native fluorescence of ibuprofen was enhanced when a host-guest complex of the analyte with beta cyclodextrin (beta-CD) was formed. So, based on this fact, a flow injection method to determine ibuprofen in different pharmaceutical preparations with fluorescence detection (lambdaem 287 nm, lambdaexc 223 nm) was developed. The calibration curve was linear over the range 6.00 - 60.0 mg L-1 of ibuprofen and the detection limit (LOD) for S/N=3 was 4.5 mg L-1. The relative standard deviation was 1.2% and the sample throughput 240 h-1. The method was validated by comparing the proposed and the official method to commercial preparation samples.Sociedade Brasileira de Química2006-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532006000700033Journal of the Brazilian Chemical Society v.17 n.7 2006reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532006000700033info:eu-repo/semantics/openAccessLista,Adriana G.Palomeque,Miriam E.Band,Beatriz S. Fernándezeng2007-01-29T00:00:00Zoai:scielo:S0103-50532006000700033Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2007-01-29T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv A fast fluorimetric flow injection method to determine ibuprofen
title A fast fluorimetric flow injection method to determine ibuprofen
spellingShingle A fast fluorimetric flow injection method to determine ibuprofen
Lista,Adriana G.
ibuprofen
FIA
spectrofluorimetry
pharmaceutical preparation
title_short A fast fluorimetric flow injection method to determine ibuprofen
title_full A fast fluorimetric flow injection method to determine ibuprofen
title_fullStr A fast fluorimetric flow injection method to determine ibuprofen
title_full_unstemmed A fast fluorimetric flow injection method to determine ibuprofen
title_sort A fast fluorimetric flow injection method to determine ibuprofen
author Lista,Adriana G.
author_facet Lista,Adriana G.
Palomeque,Miriam E.
Band,Beatriz S. Fernández
author_role author
author2 Palomeque,Miriam E.
Band,Beatriz S. Fernández
author2_role author
author
dc.contributor.author.fl_str_mv Lista,Adriana G.
Palomeque,Miriam E.
Band,Beatriz S. Fernández
dc.subject.por.fl_str_mv ibuprofen
FIA
spectrofluorimetry
pharmaceutical preparation
topic ibuprofen
FIA
spectrofluorimetry
pharmaceutical preparation
description The native fluorescence of ibuprofen was enhanced when a host-guest complex of the analyte with beta cyclodextrin (beta-CD) was formed. So, based on this fact, a flow injection method to determine ibuprofen in different pharmaceutical preparations with fluorescence detection (lambdaem 287 nm, lambdaexc 223 nm) was developed. The calibration curve was linear over the range 6.00 - 60.0 mg L-1 of ibuprofen and the detection limit (LOD) for S/N=3 was 4.5 mg L-1. The relative standard deviation was 1.2% and the sample throughput 240 h-1. The method was validated by comparing the proposed and the official method to commercial preparation samples.
publishDate 2006
dc.date.none.fl_str_mv 2006-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532006000700033
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532006000700033
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532006000700033
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.17 n.7 2006
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
_version_ 1750318167442325504

Registros relacionados