Synthesis, crystal structure and biological activity of novel diester cyclophanes

Detalhes bibliográficos
Autor(a) principal: Zhang,Pengfei
Data de Publicação: 2012
Outros Autores: Yang,Bingqin, Fang,Xianwen, Cheng,Zhao, Yang,Meipan
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532012001000002
Resumo: A series of novel diester cyclophanes was synthesized by esterification of 1,2-benzenedicarbonyl chloride with eight different diols under high dilution conditions. The structures of the compounds were verified by elemental analysis, ¹H nuclear magnetic resonance (NMR), IR spectroscopy and high resolution mass spectrometry (HRMS). The crystal structures of two compounds were characterized by single crystal X-ray diffractometry (XRD). All the new cyclophanes were evaluated for biological activities and the results showed that some of these compounds have low antibacterial or antifungal activities.
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spelling Synthesis, crystal structure and biological activity of novel diester cyclophanessynthesisester cyclophanescrystalantibacterial activityantifungal activityA series of novel diester cyclophanes was synthesized by esterification of 1,2-benzenedicarbonyl chloride with eight different diols under high dilution conditions. The structures of the compounds were verified by elemental analysis, ¹H nuclear magnetic resonance (NMR), IR spectroscopy and high resolution mass spectrometry (HRMS). The crystal structures of two compounds were characterized by single crystal X-ray diffractometry (XRD). All the new cyclophanes were evaluated for biological activities and the results showed that some of these compounds have low antibacterial or antifungal activities.Sociedade Brasileira de Química2012-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532012001000002Journal of the Brazilian Chemical Society v.23 n.10 2012reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532012005000045info:eu-repo/semantics/openAccessZhang,PengfeiYang,BingqinFang,XianwenCheng,ZhaoYang,Meipaneng2012-12-05T00:00:00Zoai:scielo:S0103-50532012001000002Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2012-12-05T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Synthesis, crystal structure and biological activity of novel diester cyclophanes
title Synthesis, crystal structure and biological activity of novel diester cyclophanes
spellingShingle Synthesis, crystal structure and biological activity of novel diester cyclophanes
Zhang,Pengfei
synthesis
ester cyclophanes
crystal
antibacterial activity
antifungal activity
title_short Synthesis, crystal structure and biological activity of novel diester cyclophanes
title_full Synthesis, crystal structure and biological activity of novel diester cyclophanes
title_fullStr Synthesis, crystal structure and biological activity of novel diester cyclophanes
title_full_unstemmed Synthesis, crystal structure and biological activity of novel diester cyclophanes
title_sort Synthesis, crystal structure and biological activity of novel diester cyclophanes
author Zhang,Pengfei
author_facet Zhang,Pengfei
Yang,Bingqin
Fang,Xianwen
Cheng,Zhao
Yang,Meipan
author_role author
author2 Yang,Bingqin
Fang,Xianwen
Cheng,Zhao
Yang,Meipan
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Zhang,Pengfei
Yang,Bingqin
Fang,Xianwen
Cheng,Zhao
Yang,Meipan
dc.subject.por.fl_str_mv synthesis
ester cyclophanes
crystal
antibacterial activity
antifungal activity
topic synthesis
ester cyclophanes
crystal
antibacterial activity
antifungal activity
description A series of novel diester cyclophanes was synthesized by esterification of 1,2-benzenedicarbonyl chloride with eight different diols under high dilution conditions. The structures of the compounds were verified by elemental analysis, ¹H nuclear magnetic resonance (NMR), IR spectroscopy and high resolution mass spectrometry (HRMS). The crystal structures of two compounds were characterized by single crystal X-ray diffractometry (XRD). All the new cyclophanes were evaluated for biological activities and the results showed that some of these compounds have low antibacterial or antifungal activities.
publishDate 2012
dc.date.none.fl_str_mv 2012-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532012001000002
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532012001000002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532012005000045
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.23 n.10 2012
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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