An easy access to two epimeric N-substituted (2S)-2-(2'-hydroxypropyl)pyrrolidines
Autor(a) principal: | |
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Data de Publicação: | 2005 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of the Brazilian Chemical Society (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532005000600017 |
Resumo: | An easy and efficient route for the synthesis of enantiomerically pure beta-aminoketones 5a, 6 and gamma-aminoalcohols 1a, 2a, 3, 4 from L-prolinol 7 and L-proline 15 is described. One of the key steps is the use of Tebbe's reagent allowing the transformation of the ester function to an enol ether without any racemization. |
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Journal of the Brazilian Chemical Society (Online) |
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An easy access to two epimeric N-substituted (2S)-2-(2'-hydroxypropyl)pyrrolidinesbeta-aminoketonesgamma-aminoalcoholsracemizationTebbe's reagentAn easy and efficient route for the synthesis of enantiomerically pure beta-aminoketones 5a, 6 and gamma-aminoalcohols 1a, 2a, 3, 4 from L-prolinol 7 and L-proline 15 is described. One of the key steps is the use of Tebbe's reagent allowing the transformation of the ester function to an enol ether without any racemization.Sociedade Brasileira de Química2005-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532005000600017Journal of the Brazilian Chemical Society v.16 n.5 2005reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532005000600017info:eu-repo/semantics/openAccessSilva,Maria Joselice eCottier,LouisSrivastava,Rajendra M.Sinou,Deniseng2005-11-09T00:00:00Zoai:scielo:S0103-50532005000600017Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2005-11-09T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
An easy access to two epimeric N-substituted (2S)-2-(2'-hydroxypropyl)pyrrolidines |
title |
An easy access to two epimeric N-substituted (2S)-2-(2'-hydroxypropyl)pyrrolidines |
spellingShingle |
An easy access to two epimeric N-substituted (2S)-2-(2'-hydroxypropyl)pyrrolidines Silva,Maria Joselice e beta-aminoketones gamma-aminoalcohols racemization Tebbe's reagent |
title_short |
An easy access to two epimeric N-substituted (2S)-2-(2'-hydroxypropyl)pyrrolidines |
title_full |
An easy access to two epimeric N-substituted (2S)-2-(2'-hydroxypropyl)pyrrolidines |
title_fullStr |
An easy access to two epimeric N-substituted (2S)-2-(2'-hydroxypropyl)pyrrolidines |
title_full_unstemmed |
An easy access to two epimeric N-substituted (2S)-2-(2'-hydroxypropyl)pyrrolidines |
title_sort |
An easy access to two epimeric N-substituted (2S)-2-(2'-hydroxypropyl)pyrrolidines |
author |
Silva,Maria Joselice e |
author_facet |
Silva,Maria Joselice e Cottier,Louis Srivastava,Rajendra M. Sinou,Denis |
author_role |
author |
author2 |
Cottier,Louis Srivastava,Rajendra M. Sinou,Denis |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Silva,Maria Joselice e Cottier,Louis Srivastava,Rajendra M. Sinou,Denis |
dc.subject.por.fl_str_mv |
beta-aminoketones gamma-aminoalcohols racemization Tebbe's reagent |
topic |
beta-aminoketones gamma-aminoalcohols racemization Tebbe's reagent |
description |
An easy and efficient route for the synthesis of enantiomerically pure beta-aminoketones 5a, 6 and gamma-aminoalcohols 1a, 2a, 3, 4 from L-prolinol 7 and L-proline 15 is described. One of the key steps is the use of Tebbe's reagent allowing the transformation of the ester function to an enol ether without any racemization. |
publishDate |
2005 |
dc.date.none.fl_str_mv |
2005-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532005000600017 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532005000600017 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0103-50532005000600017 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Journal of the Brazilian Chemical Society v.16 n.5 2005 reponame:Journal of the Brazilian Chemical Society (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Journal of the Brazilian Chemical Society (Online) |
collection |
Journal of the Brazilian Chemical Society (Online) |
repository.name.fl_str_mv |
Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
||office@jbcs.sbq.org.br |
_version_ |
1750318166579347456 |