Biosynthesis of two dihydropyrrole-polyketides from a marine-derived Penicillium citrinum

Detalhes bibliográficos
Autor(a) principal: Romminger,Stelamar
Data de Publicação: 2012
Outros Autores: Pimenta,Eli F., Nascimento,Eduardo S., Ferreira,Antonio G., Berlinck,Roberto G. S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532012001000004
Resumo: Feeding experiments with 13C-labeled precursors were performed in order to establish the biosynthesis of two N-acylated dihydropyrroles, (8E)-1-(2,3-dihydro-1H-pyrrol-1-yl)-2-methyldec8-ene-1,3-dione (1) and 1-(2,3-dihydro-1H-pyrrol-1-yl)-2-methyldecane-1,3-dione (2), isolated from the cultures of a marine-derived Penicillium citrinum. The biosynthesis of both, 1 and 2, involves the incorporation of acetate, methionine and ornithine.
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spelling Biosynthesis of two dihydropyrrole-polyketides from a marine-derived Penicillium citrinumPenicillium citrinummarine-derived fungusmixed biosynthesisdihydropyrroleFeeding experiments with 13C-labeled precursors were performed in order to establish the biosynthesis of two N-acylated dihydropyrroles, (8E)-1-(2,3-dihydro-1H-pyrrol-1-yl)-2-methyldec8-ene-1,3-dione (1) and 1-(2,3-dihydro-1H-pyrrol-1-yl)-2-methyldecane-1,3-dione (2), isolated from the cultures of a marine-derived Penicillium citrinum. The biosynthesis of both, 1 and 2, involves the incorporation of acetate, methionine and ornithine.Sociedade Brasileira de Química2012-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532012001000004Journal of the Brazilian Chemical Society v.23 n.10 2012reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532012005000046info:eu-repo/semantics/openAccessRomminger,StelamarPimenta,Eli F.Nascimento,Eduardo S.Ferreira,Antonio G.Berlinck,Roberto G. S.eng2012-12-05T00:00:00Zoai:scielo:S0103-50532012001000004Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2012-12-05T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Biosynthesis of two dihydropyrrole-polyketides from a marine-derived Penicillium citrinum
title Biosynthesis of two dihydropyrrole-polyketides from a marine-derived Penicillium citrinum
spellingShingle Biosynthesis of two dihydropyrrole-polyketides from a marine-derived Penicillium citrinum
Romminger,Stelamar
Penicillium citrinum
marine-derived fungus
mixed biosynthesis
dihydropyrrole
title_short Biosynthesis of two dihydropyrrole-polyketides from a marine-derived Penicillium citrinum
title_full Biosynthesis of two dihydropyrrole-polyketides from a marine-derived Penicillium citrinum
title_fullStr Biosynthesis of two dihydropyrrole-polyketides from a marine-derived Penicillium citrinum
title_full_unstemmed Biosynthesis of two dihydropyrrole-polyketides from a marine-derived Penicillium citrinum
title_sort Biosynthesis of two dihydropyrrole-polyketides from a marine-derived Penicillium citrinum
author Romminger,Stelamar
author_facet Romminger,Stelamar
Pimenta,Eli F.
Nascimento,Eduardo S.
Ferreira,Antonio G.
Berlinck,Roberto G. S.
author_role author
author2 Pimenta,Eli F.
Nascimento,Eduardo S.
Ferreira,Antonio G.
Berlinck,Roberto G. S.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Romminger,Stelamar
Pimenta,Eli F.
Nascimento,Eduardo S.
Ferreira,Antonio G.
Berlinck,Roberto G. S.
dc.subject.por.fl_str_mv Penicillium citrinum
marine-derived fungus
mixed biosynthesis
dihydropyrrole
topic Penicillium citrinum
marine-derived fungus
mixed biosynthesis
dihydropyrrole
description Feeding experiments with 13C-labeled precursors were performed in order to establish the biosynthesis of two N-acylated dihydropyrroles, (8E)-1-(2,3-dihydro-1H-pyrrol-1-yl)-2-methyldec8-ene-1,3-dione (1) and 1-(2,3-dihydro-1H-pyrrol-1-yl)-2-methyldecane-1,3-dione (2), isolated from the cultures of a marine-derived Penicillium citrinum. The biosynthesis of both, 1 and 2, involves the incorporation of acetate, methionine and ornithine.
publishDate 2012
dc.date.none.fl_str_mv 2012-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532012001000004
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532012001000004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532012005000046
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.23 n.10 2012
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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