Meroterpenoid Hydroquinones from Cordia globosa

Detalhes bibliográficos
Autor(a) principal: Silva,Ana Karine O.
Data de Publicação: 2016
Outros Autores: Oliveira,André Luis L. de, Pinto,Francisco das Chagas L., Lima,Karisia S. B. de, Braz-Filho,Raimundo, Silveira,Edilberto R., Pessoa,Otilia Deusdênia L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532016000300510
Resumo: Two new meroterpenoid hydroquinones,rel-(4bE,6Z,8E,9aS,10S)-1,4-dihydroxy-9a,10-dihydro-10,12-epoxy-5-methylbenzo[a]azulen-12-one andrel-(4bZ,6Z,8E,9aS,10S)-1-hydroxy-9a,10-dihydro-4,11:10,12-diepoxy-benzo[a]azulen-11,12-dione, along with the known peptide derivative (S)-N-benzoylphenylalanine-(S)-2-benzamide-3-phenylpropyl ester, were isolated from the roots of Cordia globosa. Their structures were determined by 1D and 2D nuclear magnetic resonance (NMR) spectrometry, Fourier transform infrared (FTIR) spectroscopy and high resolution atmospheric pressure chemical ionization mass spectrometry (HRAPCIMS) data analysis. The new compounds were tested against three human cancer cell lines (colon adenocarcinoma, ovarian carcinoma and glioblastoma), but none of them exhibited any activity.
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spelling Meroterpenoid Hydroquinones from Cordia globosaCordia globosaBoraginaceaehydroquinonesTwo new meroterpenoid hydroquinones,rel-(4bE,6Z,8E,9aS,10S)-1,4-dihydroxy-9a,10-dihydro-10,12-epoxy-5-methylbenzo[a]azulen-12-one andrel-(4bZ,6Z,8E,9aS,10S)-1-hydroxy-9a,10-dihydro-4,11:10,12-diepoxy-benzo[a]azulen-11,12-dione, along with the known peptide derivative (S)-N-benzoylphenylalanine-(S)-2-benzamide-3-phenylpropyl ester, were isolated from the roots of Cordia globosa. Their structures were determined by 1D and 2D nuclear magnetic resonance (NMR) spectrometry, Fourier transform infrared (FTIR) spectroscopy and high resolution atmospheric pressure chemical ionization mass spectrometry (HRAPCIMS) data analysis. The new compounds were tested against three human cancer cell lines (colon adenocarcinoma, ovarian carcinoma and glioblastoma), but none of them exhibited any activity.Sociedade Brasileira de Química2016-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532016000300510Journal of the Brazilian Chemical Society v.27 n.3 2016reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.5935/0103-5053.20150278info:eu-repo/semantics/openAccessSilva,Ana Karine O.Oliveira,André Luis L. dePinto,Francisco das Chagas L.Lima,Karisia S. B. deBraz-Filho,RaimundoSilveira,Edilberto R.Pessoa,Otilia Deusdênia L.eng2016-03-10T00:00:00Zoai:scielo:S0103-50532016000300510Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2016-03-10T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Meroterpenoid Hydroquinones from Cordia globosa
title Meroterpenoid Hydroquinones from Cordia globosa
spellingShingle Meroterpenoid Hydroquinones from Cordia globosa
Silva,Ana Karine O.
Cordia globosa
Boraginaceae
hydroquinones
title_short Meroterpenoid Hydroquinones from Cordia globosa
title_full Meroterpenoid Hydroquinones from Cordia globosa
title_fullStr Meroterpenoid Hydroquinones from Cordia globosa
title_full_unstemmed Meroterpenoid Hydroquinones from Cordia globosa
title_sort Meroterpenoid Hydroquinones from Cordia globosa
author Silva,Ana Karine O.
author_facet Silva,Ana Karine O.
Oliveira,André Luis L. de
Pinto,Francisco das Chagas L.
Lima,Karisia S. B. de
Braz-Filho,Raimundo
Silveira,Edilberto R.
Pessoa,Otilia Deusdênia L.
author_role author
author2 Oliveira,André Luis L. de
Pinto,Francisco das Chagas L.
Lima,Karisia S. B. de
Braz-Filho,Raimundo
Silveira,Edilberto R.
Pessoa,Otilia Deusdênia L.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Silva,Ana Karine O.
Oliveira,André Luis L. de
Pinto,Francisco das Chagas L.
Lima,Karisia S. B. de
Braz-Filho,Raimundo
Silveira,Edilberto R.
Pessoa,Otilia Deusdênia L.
dc.subject.por.fl_str_mv Cordia globosa
Boraginaceae
hydroquinones
topic Cordia globosa
Boraginaceae
hydroquinones
description Two new meroterpenoid hydroquinones,rel-(4bE,6Z,8E,9aS,10S)-1,4-dihydroxy-9a,10-dihydro-10,12-epoxy-5-methylbenzo[a]azulen-12-one andrel-(4bZ,6Z,8E,9aS,10S)-1-hydroxy-9a,10-dihydro-4,11:10,12-diepoxy-benzo[a]azulen-11,12-dione, along with the known peptide derivative (S)-N-benzoylphenylalanine-(S)-2-benzamide-3-phenylpropyl ester, were isolated from the roots of Cordia globosa. Their structures were determined by 1D and 2D nuclear magnetic resonance (NMR) spectrometry, Fourier transform infrared (FTIR) spectroscopy and high resolution atmospheric pressure chemical ionization mass spectrometry (HRAPCIMS) data analysis. The new compounds were tested against three human cancer cell lines (colon adenocarcinoma, ovarian carcinoma and glioblastoma), but none of them exhibited any activity.
publishDate 2016
dc.date.none.fl_str_mv 2016-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532016000300510
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532016000300510
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0103-5053.20150278
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.27 n.3 2016
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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