Analytical methods for vancomycin determination in biological fluids and in pharmaceuticals
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Química Nova (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000200029 |
Resumo: | Vancomycin is a glycopeptide antibiotic employed in the treatment of infections caused by certain methicillin-resistant staphylococci. It is indicated also for patients allergic to penicillin or when there is no response to penicillins or cephalosporins. The adequate vancomycin concentration levels in blood serum lies between 5 and 10 mg/L. Higher values are toxic, causing mainly nephrotoxicity and ototoxicity. Various analytical methods are described in the literature: spectrophotometric, immunologic, biologic and chromatographic methods. This paper reviews the main analytical methods for vancomycin determination in biological fluids and in pharmaceutical preparations. |
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Analytical methods for vancomycin determination in biological fluids and in pharmaceuticalsantibioticvancomycinquantitative analysisVancomycin is a glycopeptide antibiotic employed in the treatment of infections caused by certain methicillin-resistant staphylococci. It is indicated also for patients allergic to penicillin or when there is no response to penicillins or cephalosporins. The adequate vancomycin concentration levels in blood serum lies between 5 and 10 mg/L. Higher values are toxic, causing mainly nephrotoxicity and ototoxicity. Various analytical methods are described in the literature: spectrophotometric, immunologic, biologic and chromatographic methods. This paper reviews the main analytical methods for vancomycin determination in biological fluids and in pharmaceutical preparations.Sociedade Brasileira de Química2007-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000200029Química Nova v.30 n.2 2007reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422007000200029info:eu-repo/semantics/openAccessVila,Marta Maria Duarte CarvalhoOliveira,Robson Machado deGonçalves,Marcos MoisésTubino,Matthieueng2007-03-13T00:00:00Zoai:scielo:S0100-40422007000200029Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2007-03-13T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
Analytical methods for vancomycin determination in biological fluids and in pharmaceuticals |
title |
Analytical methods for vancomycin determination in biological fluids and in pharmaceuticals |
spellingShingle |
Analytical methods for vancomycin determination in biological fluids and in pharmaceuticals Vila,Marta Maria Duarte Carvalho antibiotic vancomycin quantitative analysis |
title_short |
Analytical methods for vancomycin determination in biological fluids and in pharmaceuticals |
title_full |
Analytical methods for vancomycin determination in biological fluids and in pharmaceuticals |
title_fullStr |
Analytical methods for vancomycin determination in biological fluids and in pharmaceuticals |
title_full_unstemmed |
Analytical methods for vancomycin determination in biological fluids and in pharmaceuticals |
title_sort |
Analytical methods for vancomycin determination in biological fluids and in pharmaceuticals |
author |
Vila,Marta Maria Duarte Carvalho |
author_facet |
Vila,Marta Maria Duarte Carvalho Oliveira,Robson Machado de Gonçalves,Marcos Moisés Tubino,Matthieu |
author_role |
author |
author2 |
Oliveira,Robson Machado de Gonçalves,Marcos Moisés Tubino,Matthieu |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Vila,Marta Maria Duarte Carvalho Oliveira,Robson Machado de Gonçalves,Marcos Moisés Tubino,Matthieu |
dc.subject.por.fl_str_mv |
antibiotic vancomycin quantitative analysis |
topic |
antibiotic vancomycin quantitative analysis |
description |
Vancomycin is a glycopeptide antibiotic employed in the treatment of infections caused by certain methicillin-resistant staphylococci. It is indicated also for patients allergic to penicillin or when there is no response to penicillins or cephalosporins. The adequate vancomycin concentration levels in blood serum lies between 5 and 10 mg/L. Higher values are toxic, causing mainly nephrotoxicity and ototoxicity. Various analytical methods are described in the literature: spectrophotometric, immunologic, biologic and chromatographic methods. This paper reviews the main analytical methods for vancomycin determination in biological fluids and in pharmaceutical preparations. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000200029 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000200029 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0100-40422007000200029 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Química Nova v.30 n.2 2007 reponame:Química Nova (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Química Nova (Online) |
collection |
Química Nova (Online) |
repository.name.fl_str_mv |
Química Nova (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
quimicanova@sbq.org.br |
_version_ |
1750318106104823808 |