Analytical methods for vancomycin determination in biological fluids and in pharmaceuticals

Detalhes bibliográficos
Autor(a) principal: Vila,Marta Maria Duarte Carvalho
Data de Publicação: 2007
Outros Autores: Oliveira,Robson Machado de, Gonçalves,Marcos Moisés, Tubino,Matthieu
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000200029
Resumo: Vancomycin is a glycopeptide antibiotic employed in the treatment of infections caused by certain methicillin-resistant staphylococci. It is indicated also for patients allergic to penicillin or when there is no response to penicillins or cephalosporins. The adequate vancomycin concentration levels in blood serum lies between 5 and 10 mg/L. Higher values are toxic, causing mainly nephrotoxicity and ototoxicity. Various analytical methods are described in the literature: spectrophotometric, immunologic, biologic and chromatographic methods. This paper reviews the main analytical methods for vancomycin determination in biological fluids and in pharmaceutical preparations.
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spelling Analytical methods for vancomycin determination in biological fluids and in pharmaceuticalsantibioticvancomycinquantitative analysisVancomycin is a glycopeptide antibiotic employed in the treatment of infections caused by certain methicillin-resistant staphylococci. It is indicated also for patients allergic to penicillin or when there is no response to penicillins or cephalosporins. The adequate vancomycin concentration levels in blood serum lies between 5 and 10 mg/L. Higher values are toxic, causing mainly nephrotoxicity and ototoxicity. Various analytical methods are described in the literature: spectrophotometric, immunologic, biologic and chromatographic methods. This paper reviews the main analytical methods for vancomycin determination in biological fluids and in pharmaceutical preparations.Sociedade Brasileira de Química2007-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000200029Química Nova v.30 n.2 2007reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422007000200029info:eu-repo/semantics/openAccessVila,Marta Maria Duarte CarvalhoOliveira,Robson Machado deGonçalves,Marcos MoisésTubino,Matthieueng2007-03-13T00:00:00Zoai:scielo:S0100-40422007000200029Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2007-03-13T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Analytical methods for vancomycin determination in biological fluids and in pharmaceuticals
title Analytical methods for vancomycin determination in biological fluids and in pharmaceuticals
spellingShingle Analytical methods for vancomycin determination in biological fluids and in pharmaceuticals
Vila,Marta Maria Duarte Carvalho
antibiotic
vancomycin
quantitative analysis
title_short Analytical methods for vancomycin determination in biological fluids and in pharmaceuticals
title_full Analytical methods for vancomycin determination in biological fluids and in pharmaceuticals
title_fullStr Analytical methods for vancomycin determination in biological fluids and in pharmaceuticals
title_full_unstemmed Analytical methods for vancomycin determination in biological fluids and in pharmaceuticals
title_sort Analytical methods for vancomycin determination in biological fluids and in pharmaceuticals
author Vila,Marta Maria Duarte Carvalho
author_facet Vila,Marta Maria Duarte Carvalho
Oliveira,Robson Machado de
Gonçalves,Marcos Moisés
Tubino,Matthieu
author_role author
author2 Oliveira,Robson Machado de
Gonçalves,Marcos Moisés
Tubino,Matthieu
author2_role author
author
author
dc.contributor.author.fl_str_mv Vila,Marta Maria Duarte Carvalho
Oliveira,Robson Machado de
Gonçalves,Marcos Moisés
Tubino,Matthieu
dc.subject.por.fl_str_mv antibiotic
vancomycin
quantitative analysis
topic antibiotic
vancomycin
quantitative analysis
description Vancomycin is a glycopeptide antibiotic employed in the treatment of infections caused by certain methicillin-resistant staphylococci. It is indicated also for patients allergic to penicillin or when there is no response to penicillins or cephalosporins. The adequate vancomycin concentration levels in blood serum lies between 5 and 10 mg/L. Higher values are toxic, causing mainly nephrotoxicity and ototoxicity. Various analytical methods are described in the literature: spectrophotometric, immunologic, biologic and chromatographic methods. This paper reviews the main analytical methods for vancomycin determination in biological fluids and in pharmaceutical preparations.
publishDate 2007
dc.date.none.fl_str_mv 2007-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000200029
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000200029
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-40422007000200029
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.30 n.2 2007
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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