Spectrophotometric determination of catecholamine using vanadium and eriochrome cyanine r

Detalhes bibliográficos
Autor(a) principal: Nagaraja,Padmarajaiah
Data de Publicação: 2011
Outros Autores: Shrestha,Ashwinee Kumar, Shivakumar,Anantharaman, Al-Tayar,Naef Ghallab Saeed, Gowda,Avinask K.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000300002
Resumo: A highly sensitive spectrophotometric method for the analysis of catecholamine drugs; L-dopa and methyldopa, is described. The analysis is based on the reaction of drug molecules with vanadium (V) which is reduced to vanadium (IV) and form complex with eriochrome cyanine R to give products having maximum absorbance (lmax) at 565 nm. Beer's law is obeyed in the range 0.028-0.84 and 0.099-0.996 mg mL-1 for L-dopa and methyldopa, respectively. The statistical analysis as well as comparison with reported methods demonstrated high precision and accuracy of the proposed method. The method was successfully applied in the analysis of pharmaceutical preparations.
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spelling Spectrophotometric determination of catecholamine using vanadium and eriochrome cyanine rL-dopamethyldopavanadiumA highly sensitive spectrophotometric method for the analysis of catecholamine drugs; L-dopa and methyldopa, is described. The analysis is based on the reaction of drug molecules with vanadium (V) which is reduced to vanadium (IV) and form complex with eriochrome cyanine R to give products having maximum absorbance (lmax) at 565 nm. Beer's law is obeyed in the range 0.028-0.84 and 0.099-0.996 mg mL-1 for L-dopa and methyldopa, respectively. The statistical analysis as well as comparison with reported methods demonstrated high precision and accuracy of the proposed method. The method was successfully applied in the analysis of pharmaceutical preparations.Sociedade Brasileira de Química2011-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000300002Química Nova v.34 n.3 2011reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422011000300002info:eu-repo/semantics/openAccessNagaraja,PadmarajaiahShrestha,Ashwinee KumarShivakumar,AnantharamanAl-Tayar,Naef Ghallab SaeedGowda,Avinask K.eng2011-04-12T00:00:00Zoai:scielo:S0100-40422011000300002Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2011-04-12T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Spectrophotometric determination of catecholamine using vanadium and eriochrome cyanine r
title Spectrophotometric determination of catecholamine using vanadium and eriochrome cyanine r
spellingShingle Spectrophotometric determination of catecholamine using vanadium and eriochrome cyanine r
Nagaraja,Padmarajaiah
L-dopa
methyldopa
vanadium
title_short Spectrophotometric determination of catecholamine using vanadium and eriochrome cyanine r
title_full Spectrophotometric determination of catecholamine using vanadium and eriochrome cyanine r
title_fullStr Spectrophotometric determination of catecholamine using vanadium and eriochrome cyanine r
title_full_unstemmed Spectrophotometric determination of catecholamine using vanadium and eriochrome cyanine r
title_sort Spectrophotometric determination of catecholamine using vanadium and eriochrome cyanine r
author Nagaraja,Padmarajaiah
author_facet Nagaraja,Padmarajaiah
Shrestha,Ashwinee Kumar
Shivakumar,Anantharaman
Al-Tayar,Naef Ghallab Saeed
Gowda,Avinask K.
author_role author
author2 Shrestha,Ashwinee Kumar
Shivakumar,Anantharaman
Al-Tayar,Naef Ghallab Saeed
Gowda,Avinask K.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Nagaraja,Padmarajaiah
Shrestha,Ashwinee Kumar
Shivakumar,Anantharaman
Al-Tayar,Naef Ghallab Saeed
Gowda,Avinask K.
dc.subject.por.fl_str_mv L-dopa
methyldopa
vanadium
topic L-dopa
methyldopa
vanadium
description A highly sensitive spectrophotometric method for the analysis of catecholamine drugs; L-dopa and methyldopa, is described. The analysis is based on the reaction of drug molecules with vanadium (V) which is reduced to vanadium (IV) and form complex with eriochrome cyanine R to give products having maximum absorbance (lmax) at 565 nm. Beer's law is obeyed in the range 0.028-0.84 and 0.099-0.996 mg mL-1 for L-dopa and methyldopa, respectively. The statistical analysis as well as comparison with reported methods demonstrated high precision and accuracy of the proposed method. The method was successfully applied in the analysis of pharmaceutical preparations.
publishDate 2011
dc.date.none.fl_str_mv 2011-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000300002
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000300002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-40422011000300002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.34 n.3 2011
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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