Prevalence of COVID-19, kidney damage profile and death in intensive care during the pandemic
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , |
Tipo de documento: | preprint |
Idioma: | por |
Título da fonte: | SciELO Preprints |
Texto Completo: | https://preprints.scielo.org/index.php/scielo/preprint/view/4754 |
Resumo: | Introduction: the acute kidney injury is one of the main complications of SARs-Cov-2 infection. Objective: identify the COVID-19 prevalence and kidney damage of evaluated patients followed up by nephrology team in an intensive care unit. Materials and Methods: adults and elderly people of both genders followed up by the nephrology team and performed the RT PCR test for COVID were included on this study. For analysis and comparison, the patients were divided in RTP PCR positive and negative groups. To assess the kidney damage impact on death rates another analysis was performed considering the death or the absence of death as outcome. Results: the prevalence of COVID-19 was 58.5% and the prevalence of AKI was 75.0% among the 176 patients. More than half of patients (55.2%) undergoing renal replacement therapy tested positive for COVID-19. On the evaluation of Charlson Comorbidity Index was identified statistically significant difference in the proportions of the negative and positive COVID-19 groups in scores 0, 1 and 2. The second analysis identified a significant association between kidney disease and death in the ICU (p < 0.05). Patients with CKD died less 13/98 (13.3%) when compared to those with AKI 85/98 (86.7%). When they had both COVID-19 and AKI, the mortality rate was 69.0%. Conclusion: the prevalence of COVID-19 in patients undergoing intensive care during the first semester of 2021 was higher than 50% and the AKI prevalence in patients tested positive for COVID-19 was higher than 80%. The death rates among the patients with AKI and COVID-19 simultaneously were upper than 60%. |
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Prevalence of COVID-19, kidney damage profile and death in intensive care during the pandemicPrevalência da COVID-19, perfil do acometimento renal e óbito em terapia intensiva durante a pandemiaInjúria renal agudaTerapia IntensivaPandemia COVID-19Intensive CareAcute kidney Injury COVID-19PandemicIntroduction: the acute kidney injury is one of the main complications of SARs-Cov-2 infection. Objective: identify the COVID-19 prevalence and kidney damage of evaluated patients followed up by nephrology team in an intensive care unit. Materials and Methods: adults and elderly people of both genders followed up by the nephrology team and performed the RT PCR test for COVID were included on this study. For analysis and comparison, the patients were divided in RTP PCR positive and negative groups. To assess the kidney damage impact on death rates another analysis was performed considering the death or the absence of death as outcome. Results: the prevalence of COVID-19 was 58.5% and the prevalence of AKI was 75.0% among the 176 patients. More than half of patients (55.2%) undergoing renal replacement therapy tested positive for COVID-19. On the evaluation of Charlson Comorbidity Index was identified statistically significant difference in the proportions of the negative and positive COVID-19 groups in scores 0, 1 and 2. The second analysis identified a significant association between kidney disease and death in the ICU (p < 0.05). Patients with CKD died less 13/98 (13.3%) when compared to those with AKI 85/98 (86.7%). When they had both COVID-19 and AKI, the mortality rate was 69.0%. Conclusion: the prevalence of COVID-19 in patients undergoing intensive care during the first semester of 2021 was higher than 50% and the AKI prevalence in patients tested positive for COVID-19 was higher than 80%. The death rates among the patients with AKI and COVID-19 simultaneously were upper than 60%.Introdução: entre as principais complicações da infecção do SARs-Cov-2 está a Insuficiência renal aguda. Objetivo: identificar a prevalência de COVID-19 e acometimento renal em pacientes avaliados e acompanhados pela equipe de nefrologia em centro de tratamento intensivo. Material e Métodos: participaram adultos e idosos de ambos os sexos acompanhados pela equipe de nefrologia e que realizaram o teste RT PCR para COVID. Para análise e comparação os pacientes foram agrupados em RTP PCR positivo e negativo. Para avaliar o impacto do acometimento renal nas taxas de óbito outra análise foi realizada considerando como desfecho evolução a óbito ou não. Resultados: incluídos 176 pacientes sendo a prevalência de COVID-19 58,5% e IRA 75%. Dos pacientes que realizaram Terapia Renal Substitutiva, mais da metade (55,2%) tinham COVID 19 +. O índice de Charlson identificou-se diferença estatisticamente significativa nas proporções dos grupos COVID-19 negativo e positivo nos índices 0, 1 e 2. A segunda análise identificou associação significativa entre doença renal e óbito no CTI (p < 0,05). Os pacientes com DRC evoluíram menos a óbito 13/98 (13,3%) quando comparados com aqueles com IRA 85/98 (86,7%). E quando tinham simultaneamente o COVID 19 e a IRA a taxa de mortalidade foi de 69,0%. Conclusão: A prevalência da COVID-19 em pacientes internados no CTI adulto durante o primeiro semestre de 2021 foi acima de 50% e a prevalência de IRA nos pacientes positivos ultrapassou a marca dos 80%. A taxa de óbito entre os pacientes com IRA e COVID 19 + simultâneos ultrapassou 60%.SciELO PreprintsSciELO PreprintsSciELO Preprints2022-09-19info:eu-repo/semantics/preprintinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://preprints.scielo.org/index.php/scielo/preprint/view/475410.1590/SciELOPreprints.4754porhttps://preprints.scielo.org/index.php/scielo/article/view/4754/9205Copyright (c) 2022 Yoshimi José Ávila Watanabe, Lívia Maria Rezende Carvalho, João Victor Marques Guedes, Alba Otonihttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessWatanabe, Yoshimi José Ávila Carvalho, Lívia Maria RezendeGuedes, João Victor MarquesOtoni, Albareponame:SciELO Preprintsinstname:SciELOinstacron:SCI2022-09-17T15:43:59Zoai:ops.preprints.scielo.org:preprint/4754Servidor de preprintshttps://preprints.scielo.org/index.php/scieloONGhttps://preprints.scielo.org/index.php/scielo/oaiscielo.submission@scielo.orgopendoar:2022-09-17T15:43:59SciELO Preprints - SciELOfalse |
dc.title.none.fl_str_mv |
Prevalence of COVID-19, kidney damage profile and death in intensive care during the pandemic Prevalência da COVID-19, perfil do acometimento renal e óbito em terapia intensiva durante a pandemia |
title |
Prevalence of COVID-19, kidney damage profile and death in intensive care during the pandemic |
spellingShingle |
Prevalence of COVID-19, kidney damage profile and death in intensive care during the pandemic Watanabe, Yoshimi José Ávila Injúria renal aguda Terapia Intensiva Pandemia COVID-19 Intensive Care Acute kidney Injury COVID-19 Pandemic |
title_short |
Prevalence of COVID-19, kidney damage profile and death in intensive care during the pandemic |
title_full |
Prevalence of COVID-19, kidney damage profile and death in intensive care during the pandemic |
title_fullStr |
Prevalence of COVID-19, kidney damage profile and death in intensive care during the pandemic |
title_full_unstemmed |
Prevalence of COVID-19, kidney damage profile and death in intensive care during the pandemic |
title_sort |
Prevalence of COVID-19, kidney damage profile and death in intensive care during the pandemic |
author |
Watanabe, Yoshimi José Ávila |
author_facet |
Watanabe, Yoshimi José Ávila Carvalho, Lívia Maria Rezende Guedes, João Victor Marques Otoni, Alba |
author_role |
author |
author2 |
Carvalho, Lívia Maria Rezende Guedes, João Victor Marques Otoni, Alba |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Watanabe, Yoshimi José Ávila Carvalho, Lívia Maria Rezende Guedes, João Victor Marques Otoni, Alba |
dc.subject.por.fl_str_mv |
Injúria renal aguda Terapia Intensiva Pandemia COVID-19 Intensive Care Acute kidney Injury COVID-19 Pandemic |
topic |
Injúria renal aguda Terapia Intensiva Pandemia COVID-19 Intensive Care Acute kidney Injury COVID-19 Pandemic |
description |
Introduction: the acute kidney injury is one of the main complications of SARs-Cov-2 infection. Objective: identify the COVID-19 prevalence and kidney damage of evaluated patients followed up by nephrology team in an intensive care unit. Materials and Methods: adults and elderly people of both genders followed up by the nephrology team and performed the RT PCR test for COVID were included on this study. For analysis and comparison, the patients were divided in RTP PCR positive and negative groups. To assess the kidney damage impact on death rates another analysis was performed considering the death or the absence of death as outcome. Results: the prevalence of COVID-19 was 58.5% and the prevalence of AKI was 75.0% among the 176 patients. More than half of patients (55.2%) undergoing renal replacement therapy tested positive for COVID-19. On the evaluation of Charlson Comorbidity Index was identified statistically significant difference in the proportions of the negative and positive COVID-19 groups in scores 0, 1 and 2. The second analysis identified a significant association between kidney disease and death in the ICU (p < 0.05). Patients with CKD died less 13/98 (13.3%) when compared to those with AKI 85/98 (86.7%). When they had both COVID-19 and AKI, the mortality rate was 69.0%. Conclusion: the prevalence of COVID-19 in patients undergoing intensive care during the first semester of 2021 was higher than 50% and the AKI prevalence in patients tested positive for COVID-19 was higher than 80%. The death rates among the patients with AKI and COVID-19 simultaneously were upper than 60%. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-09-19 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/preprint info:eu-repo/semantics/publishedVersion |
format |
preprint |
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publishedVersion |
dc.identifier.uri.fl_str_mv |
https://preprints.scielo.org/index.php/scielo/preprint/view/4754 10.1590/SciELOPreprints.4754 |
url |
https://preprints.scielo.org/index.php/scielo/preprint/view/4754 |
identifier_str_mv |
10.1590/SciELOPreprints.4754 |
dc.language.iso.fl_str_mv |
por |
language |
por |
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https://preprints.scielo.org/index.php/scielo/article/view/4754/9205 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
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openAccess |
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application/pdf |
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SciELO Preprints SciELO Preprints SciELO Preprints |
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SciELO Preprints SciELO Preprints SciELO Preprints |
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SciELO Preprints - SciELO |
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