Glycogen levels and energy status of the liver of fasting rats with diabetes types 1 and 2

Detalhes bibliográficos
Autor(a) principal: Oliveira,Denise Silva de
Data de Publicação: 2007
Outros Autores: Amado,Ciomar Aparecida Bersani, Martini,Mirian Carvalho, Suzuki-Kemmelmeier,Fumie, Bracht,Adelar
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000500006
Resumo: Glycogen levels and the energy status of livers from fasting rats with diabetes types 1 and 2 were measured. After a 24 h fast, the hepatic glycogen levels of rats with diabetes1 and diabetes2 were, 18.7 and 2.6 times higher, respectively, than those of livers from the normal rats. In diabetes1 rats, the glycogen levels decreased when the fasting period was extended to 48 and 72 h. The opposite occurred with the control and diabetes2 rats. Consistently, glucose release by the perfused livers from diabetes1 rats was considerably higher during at least 60 minutes after initiating perfusion. The hepatic ATP content of diabetes1 rats was similar to that of the control rats; in diabetes2 rats, the hepatic ATP content was increased. It could be concluded that regulation of glycogen deposition and degradation in rats with diabetes1 differed markedly from that of rats with diabetes2 which, in turn, behaved similarly to normal healthy rats.
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spelling Glycogen levels and energy status of the liver of fasting rats with diabetes types 1 and 2Diabetes type 1diabetes type 2ratshepatic glycogenhepatic energy statusGlycogen levels and the energy status of livers from fasting rats with diabetes types 1 and 2 were measured. After a 24 h fast, the hepatic glycogen levels of rats with diabetes1 and diabetes2 were, 18.7 and 2.6 times higher, respectively, than those of livers from the normal rats. In diabetes1 rats, the glycogen levels decreased when the fasting period was extended to 48 and 72 h. The opposite occurred with the control and diabetes2 rats. Consistently, glucose release by the perfused livers from diabetes1 rats was considerably higher during at least 60 minutes after initiating perfusion. The hepatic ATP content of diabetes1 rats was similar to that of the control rats; in diabetes2 rats, the hepatic ATP content was increased. It could be concluded that regulation of glycogen deposition and degradation in rats with diabetes1 differed markedly from that of rats with diabetes2 which, in turn, behaved similarly to normal healthy rats.Instituto de Tecnologia do Paraná - Tecpar2007-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000500006Brazilian Archives of Biology and Technology v.50 n.5 2007reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132007000500006info:eu-repo/semantics/openAccessOliveira,Denise Silva deAmado,Ciomar Aparecida BersaniMartini,Mirian CarvalhoSuzuki-Kemmelmeier,FumieBracht,Adelareng2007-11-23T00:00:00Zoai:scielo:S1516-89132007000500006Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2007-11-23T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Glycogen levels and energy status of the liver of fasting rats with diabetes types 1 and 2
title Glycogen levels and energy status of the liver of fasting rats with diabetes types 1 and 2
spellingShingle Glycogen levels and energy status of the liver of fasting rats with diabetes types 1 and 2
Oliveira,Denise Silva de
Diabetes type 1
diabetes type 2
rats
hepatic glycogen
hepatic energy status
title_short Glycogen levels and energy status of the liver of fasting rats with diabetes types 1 and 2
title_full Glycogen levels and energy status of the liver of fasting rats with diabetes types 1 and 2
title_fullStr Glycogen levels and energy status of the liver of fasting rats with diabetes types 1 and 2
title_full_unstemmed Glycogen levels and energy status of the liver of fasting rats with diabetes types 1 and 2
title_sort Glycogen levels and energy status of the liver of fasting rats with diabetes types 1 and 2
author Oliveira,Denise Silva de
author_facet Oliveira,Denise Silva de
Amado,Ciomar Aparecida Bersani
Martini,Mirian Carvalho
Suzuki-Kemmelmeier,Fumie
Bracht,Adelar
author_role author
author2 Amado,Ciomar Aparecida Bersani
Martini,Mirian Carvalho
Suzuki-Kemmelmeier,Fumie
Bracht,Adelar
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Oliveira,Denise Silva de
Amado,Ciomar Aparecida Bersani
Martini,Mirian Carvalho
Suzuki-Kemmelmeier,Fumie
Bracht,Adelar
dc.subject.por.fl_str_mv Diabetes type 1
diabetes type 2
rats
hepatic glycogen
hepatic energy status
topic Diabetes type 1
diabetes type 2
rats
hepatic glycogen
hepatic energy status
description Glycogen levels and the energy status of livers from fasting rats with diabetes types 1 and 2 were measured. After a 24 h fast, the hepatic glycogen levels of rats with diabetes1 and diabetes2 were, 18.7 and 2.6 times higher, respectively, than those of livers from the normal rats. In diabetes1 rats, the glycogen levels decreased when the fasting period was extended to 48 and 72 h. The opposite occurred with the control and diabetes2 rats. Consistently, glucose release by the perfused livers from diabetes1 rats was considerably higher during at least 60 minutes after initiating perfusion. The hepatic ATP content of diabetes1 rats was similar to that of the control rats; in diabetes2 rats, the hepatic ATP content was increased. It could be concluded that regulation of glycogen deposition and degradation in rats with diabetes1 differed markedly from that of rats with diabetes2 which, in turn, behaved similarly to normal healthy rats.
publishDate 2007
dc.date.none.fl_str_mv 2007-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000500006
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000500006
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132007000500006
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.50 n.5 2007
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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