Determination of N-nitrosamines and N-nitrosables substances in rubber teats and sothers by GC-TEA
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Archives of Biology and Technology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000200012 |
Resumo: | N-Nitrosamines are receiving special attention because they present high mutagenic and carcinogenic potential. They can be found in several areas. In rubber, for example, they can be found in Nipples and Pacifiers. Spiegelhalder and Pressumann, have observed that N-Nitrosamines present in nipples and pacifiers could easily migrate to artificial saliva. They have also observed that a considerable amount of N-Nitrosamines precursors, such as nitrosable amines, could migrate to saliva, increasing the possibility of N-Nitrosamines formation into the stomach of living beings. In 80's, Holland, Germany and FDA-U.S.A. have established volatile N-Nitrosamines limit levels. In 2002, in Brazil, limit levels came through Resolução RDC n° 221 of ANVISA. This resolution refers to NBR10334 and NBR 13793 standards where limits and analysis methods are specified. In this work SENAICETEPO presents the method adopted for determination of N-Nitrosamines and N-Nitrosables in nipples and pacifiers. The detection and determination limits of the analytical system as well the method uncertainty were evaluated, in order to demonstrate the adequacy of this technique to comply with the requirements of NBR10334/2003 and NBR 13793/2003 standard. |
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Determination of N-nitrosamines and N-nitrosables substances in rubber teats and sothers by GC-TEAN-Nitrosaminesmethodnipples and pacifiersN-Nitrosamines are receiving special attention because they present high mutagenic and carcinogenic potential. They can be found in several areas. In rubber, for example, they can be found in Nipples and Pacifiers. Spiegelhalder and Pressumann, have observed that N-Nitrosamines present in nipples and pacifiers could easily migrate to artificial saliva. They have also observed that a considerable amount of N-Nitrosamines precursors, such as nitrosable amines, could migrate to saliva, increasing the possibility of N-Nitrosamines formation into the stomach of living beings. In 80's, Holland, Germany and FDA-U.S.A. have established volatile N-Nitrosamines limit levels. In 2002, in Brazil, limit levels came through Resolução RDC n° 221 of ANVISA. This resolution refers to NBR10334 and NBR 13793 standards where limits and analysis methods are specified. In this work SENAICETEPO presents the method adopted for determination of N-Nitrosamines and N-Nitrosables in nipples and pacifiers. The detection and determination limits of the analytical system as well the method uncertainty were evaluated, in order to demonstrate the adequacy of this technique to comply with the requirements of NBR10334/2003 and NBR 13793/2003 standard.Instituto de Tecnologia do Paraná - Tecpar2006-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000200012Brazilian Archives of Biology and Technology v.49 n.spe 2006reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132006000200012info:eu-repo/semantics/openAccessVieira,Eleno RodriguesPierozan,Nilso JoséLovison,Vivianeeng2006-03-30T00:00:00Zoai:scielo:S1516-89132006000200012Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2006-03-30T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false |
dc.title.none.fl_str_mv |
Determination of N-nitrosamines and N-nitrosables substances in rubber teats and sothers by GC-TEA |
title |
Determination of N-nitrosamines and N-nitrosables substances in rubber teats and sothers by GC-TEA |
spellingShingle |
Determination of N-nitrosamines and N-nitrosables substances in rubber teats and sothers by GC-TEA Vieira,Eleno Rodrigues N-Nitrosamines method nipples and pacifiers |
title_short |
Determination of N-nitrosamines and N-nitrosables substances in rubber teats and sothers by GC-TEA |
title_full |
Determination of N-nitrosamines and N-nitrosables substances in rubber teats and sothers by GC-TEA |
title_fullStr |
Determination of N-nitrosamines and N-nitrosables substances in rubber teats and sothers by GC-TEA |
title_full_unstemmed |
Determination of N-nitrosamines and N-nitrosables substances in rubber teats and sothers by GC-TEA |
title_sort |
Determination of N-nitrosamines and N-nitrosables substances in rubber teats and sothers by GC-TEA |
author |
Vieira,Eleno Rodrigues |
author_facet |
Vieira,Eleno Rodrigues Pierozan,Nilso José Lovison,Viviane |
author_role |
author |
author2 |
Pierozan,Nilso José Lovison,Viviane |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Vieira,Eleno Rodrigues Pierozan,Nilso José Lovison,Viviane |
dc.subject.por.fl_str_mv |
N-Nitrosamines method nipples and pacifiers |
topic |
N-Nitrosamines method nipples and pacifiers |
description |
N-Nitrosamines are receiving special attention because they present high mutagenic and carcinogenic potential. They can be found in several areas. In rubber, for example, they can be found in Nipples and Pacifiers. Spiegelhalder and Pressumann, have observed that N-Nitrosamines present in nipples and pacifiers could easily migrate to artificial saliva. They have also observed that a considerable amount of N-Nitrosamines precursors, such as nitrosable amines, could migrate to saliva, increasing the possibility of N-Nitrosamines formation into the stomach of living beings. In 80's, Holland, Germany and FDA-U.S.A. have established volatile N-Nitrosamines limit levels. In 2002, in Brazil, limit levels came through Resolução RDC n° 221 of ANVISA. This resolution refers to NBR10334 and NBR 13793 standards where limits and analysis methods are specified. In this work SENAICETEPO presents the method adopted for determination of N-Nitrosamines and N-Nitrosables in nipples and pacifiers. The detection and determination limits of the analytical system as well the method uncertainty were evaluated, in order to demonstrate the adequacy of this technique to comply with the requirements of NBR10334/2003 and NBR 13793/2003 standard. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000200012 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000200012 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1516-89132006000200012 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
dc.source.none.fl_str_mv |
Brazilian Archives of Biology and Technology v.49 n.spe 2006 reponame:Brazilian Archives of Biology and Technology instname:Instituto de Tecnologia do Paraná (Tecpar) instacron:TECPAR |
instname_str |
Instituto de Tecnologia do Paraná (Tecpar) |
instacron_str |
TECPAR |
institution |
TECPAR |
reponame_str |
Brazilian Archives of Biology and Technology |
collection |
Brazilian Archives of Biology and Technology |
repository.name.fl_str_mv |
Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar) |
repository.mail.fl_str_mv |
babt@tecpar.br||babt@tecpar.br |
_version_ |
1750318271026954240 |