Immune response after rabies oral immunization in mice

Detalhes bibliográficos
Autor(a) principal: Silva,Camila Sloboda Pacheco da
Data de Publicação: 2013
Outros Autores: Krüger,Ernesto Renato, Agottani,Jorge Victor Bacila, Oliveira,Rubens Chaguri de, Pereira,Sandro, Penha,Tânia Regina, Ollhoff,Rüdiger Daniel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000600006
Resumo: The objective of this study was to formulate an anti-rabies oral vaccine from the cell culture vaccine PV TECPAR to elicit the production of antibodies against the rabies in mice. A vaccine was developed using 10(7.5) DL50/0.03 ml viral antigens homogenised in lanovaseline to facilitate oral administration. Mice were vaccinated two times for seroconversion. Sera of the vaccinated mice showed a higher level of antibody production than the control group. These results could be used to direct the development of an anti-rabies oral vaccine.
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network_name_str Brazilian Archives of Biology and Technology
repository_id_str
spelling Immune response after rabies oral immunization in miceRabiesOral vaccineMiceELISAThe objective of this study was to formulate an anti-rabies oral vaccine from the cell culture vaccine PV TECPAR to elicit the production of antibodies against the rabies in mice. A vaccine was developed using 10(7.5) DL50/0.03 ml viral antigens homogenised in lanovaseline to facilitate oral administration. Mice were vaccinated two times for seroconversion. Sera of the vaccinated mice showed a higher level of antibody production than the control group. These results could be used to direct the development of an anti-rabies oral vaccine.Instituto de Tecnologia do Paraná - Tecpar2013-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000600006Brazilian Archives of Biology and Technology v.56 n.6 2013reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132013005000001info:eu-repo/semantics/openAccessSilva,Camila Sloboda Pacheco daKrüger,Ernesto RenatoAgottani,Jorge Victor BacilaOliveira,Rubens Chaguri dePereira,SandroPenha,Tânia ReginaOllhoff,Rüdiger Danieleng2014-01-15T00:00:00Zoai:scielo:S1516-89132013000600006Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2014-01-15T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Immune response after rabies oral immunization in mice
title Immune response after rabies oral immunization in mice
spellingShingle Immune response after rabies oral immunization in mice
Silva,Camila Sloboda Pacheco da
Rabies
Oral vaccine
Mice
ELISA
title_short Immune response after rabies oral immunization in mice
title_full Immune response after rabies oral immunization in mice
title_fullStr Immune response after rabies oral immunization in mice
title_full_unstemmed Immune response after rabies oral immunization in mice
title_sort Immune response after rabies oral immunization in mice
author Silva,Camila Sloboda Pacheco da
author_facet Silva,Camila Sloboda Pacheco da
Krüger,Ernesto Renato
Agottani,Jorge Victor Bacila
Oliveira,Rubens Chaguri de
Pereira,Sandro
Penha,Tânia Regina
Ollhoff,Rüdiger Daniel
author_role author
author2 Krüger,Ernesto Renato
Agottani,Jorge Victor Bacila
Oliveira,Rubens Chaguri de
Pereira,Sandro
Penha,Tânia Regina
Ollhoff,Rüdiger Daniel
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Silva,Camila Sloboda Pacheco da
Krüger,Ernesto Renato
Agottani,Jorge Victor Bacila
Oliveira,Rubens Chaguri de
Pereira,Sandro
Penha,Tânia Regina
Ollhoff,Rüdiger Daniel
dc.subject.por.fl_str_mv Rabies
Oral vaccine
Mice
ELISA
topic Rabies
Oral vaccine
Mice
ELISA
description The objective of this study was to formulate an anti-rabies oral vaccine from the cell culture vaccine PV TECPAR to elicit the production of antibodies against the rabies in mice. A vaccine was developed using 10(7.5) DL50/0.03 ml viral antigens homogenised in lanovaseline to facilitate oral administration. Mice were vaccinated two times for seroconversion. Sera of the vaccinated mice showed a higher level of antibody production than the control group. These results could be used to direct the development of an anti-rabies oral vaccine.
publishDate 2013
dc.date.none.fl_str_mv 2013-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000600006
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000600006
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132013005000001
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.56 n.6 2013
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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