Effects of Low-level Laser Therapy on Muscle Repair in Rats with Chronic Alcohol Intake
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Archives of Biology and Technology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100319 |
Resumo: | ABSTRACT This study aimed to investigate the effects of low-level laser therapy (LLLT) on muscle repair in rats with chronic alcohol intake. Thirty male Wistar rats were distributed into three groups: injured tibialis anterior (TA) muscle without treatment (IC); chronic ingestion of alcohol plus injured TA muscle (AI); and chronic ingestion of alcohol plus injured TA plus LLLT (AIL). Each group was divided into two different subgroups, and rats were sacrificed on days 3 and 7 post-injury. Morphological features in the injured areas were similar with or without alcohol intake (IC and AI); however, LLLT promoted a decrease in the number of inflammatory cells and destroyed zones, as well as improved tissue organization (AIL). In general, alcohol intake caused a decrease in myogenic regulatory factors (MyoD and myogenin) and vascular endothelial growth factor in the AI group. Moreover, LLLT promoted recovery of these factors to the same level as in animals without alcohol intake (IC and AIL). LLLT was able to increase the expression of myogenic and vascular growth factors and stimulate skeletal muscle regeneration in rats with chronic alcohol intake. |
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Brazilian Archives of Biology and Technology |
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Effects of Low-level Laser Therapy on Muscle Repair in Rats with Chronic Alcohol IntakeLow-level laser therapyalcohol intakemuscle repairABSTRACT This study aimed to investigate the effects of low-level laser therapy (LLLT) on muscle repair in rats with chronic alcohol intake. Thirty male Wistar rats were distributed into three groups: injured tibialis anterior (TA) muscle without treatment (IC); chronic ingestion of alcohol plus injured TA muscle (AI); and chronic ingestion of alcohol plus injured TA plus LLLT (AIL). Each group was divided into two different subgroups, and rats were sacrificed on days 3 and 7 post-injury. Morphological features in the injured areas were similar with or without alcohol intake (IC and AI); however, LLLT promoted a decrease in the number of inflammatory cells and destroyed zones, as well as improved tissue organization (AIL). In general, alcohol intake caused a decrease in myogenic regulatory factors (MyoD and myogenin) and vascular endothelial growth factor in the AI group. Moreover, LLLT promoted recovery of these factors to the same level as in animals without alcohol intake (IC and AIL). LLLT was able to increase the expression of myogenic and vascular growth factors and stimulate skeletal muscle regeneration in rats with chronic alcohol intake.Instituto de Tecnologia do Paraná - Tecpar2018-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100319Brazilian Archives of Biology and Technology v.61 2018reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/1678-4324-2018161223info:eu-repo/semantics/openAccessCespedes,Isabel CristinaAssis,LiviaThomaz,Rafael MoraesPanfilio,Carlos EduardoGonçalves,LuisMuniz,Ana Claudia Rennoeng2018-11-09T00:00:00Zoai:scielo:S1516-89132018000100319Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2018-11-09T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false |
dc.title.none.fl_str_mv |
Effects of Low-level Laser Therapy on Muscle Repair in Rats with Chronic Alcohol Intake |
title |
Effects of Low-level Laser Therapy on Muscle Repair in Rats with Chronic Alcohol Intake |
spellingShingle |
Effects of Low-level Laser Therapy on Muscle Repair in Rats with Chronic Alcohol Intake Cespedes,Isabel Cristina Low-level laser therapy alcohol intake muscle repair |
title_short |
Effects of Low-level Laser Therapy on Muscle Repair in Rats with Chronic Alcohol Intake |
title_full |
Effects of Low-level Laser Therapy on Muscle Repair in Rats with Chronic Alcohol Intake |
title_fullStr |
Effects of Low-level Laser Therapy on Muscle Repair in Rats with Chronic Alcohol Intake |
title_full_unstemmed |
Effects of Low-level Laser Therapy on Muscle Repair in Rats with Chronic Alcohol Intake |
title_sort |
Effects of Low-level Laser Therapy on Muscle Repair in Rats with Chronic Alcohol Intake |
author |
Cespedes,Isabel Cristina |
author_facet |
Cespedes,Isabel Cristina Assis,Livia Thomaz,Rafael Moraes Panfilio,Carlos Eduardo Gonçalves,Luis Muniz,Ana Claudia Renno |
author_role |
author |
author2 |
Assis,Livia Thomaz,Rafael Moraes Panfilio,Carlos Eduardo Gonçalves,Luis Muniz,Ana Claudia Renno |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Cespedes,Isabel Cristina Assis,Livia Thomaz,Rafael Moraes Panfilio,Carlos Eduardo Gonçalves,Luis Muniz,Ana Claudia Renno |
dc.subject.por.fl_str_mv |
Low-level laser therapy alcohol intake muscle repair |
topic |
Low-level laser therapy alcohol intake muscle repair |
description |
ABSTRACT This study aimed to investigate the effects of low-level laser therapy (LLLT) on muscle repair in rats with chronic alcohol intake. Thirty male Wistar rats were distributed into three groups: injured tibialis anterior (TA) muscle without treatment (IC); chronic ingestion of alcohol plus injured TA muscle (AI); and chronic ingestion of alcohol plus injured TA plus LLLT (AIL). Each group was divided into two different subgroups, and rats were sacrificed on days 3 and 7 post-injury. Morphological features in the injured areas were similar with or without alcohol intake (IC and AI); however, LLLT promoted a decrease in the number of inflammatory cells and destroyed zones, as well as improved tissue organization (AIL). In general, alcohol intake caused a decrease in myogenic regulatory factors (MyoD and myogenin) and vascular endothelial growth factor in the AI group. Moreover, LLLT promoted recovery of these factors to the same level as in animals without alcohol intake (IC and AIL). LLLT was able to increase the expression of myogenic and vascular growth factors and stimulate skeletal muscle regeneration in rats with chronic alcohol intake. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100319 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100319 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1678-4324-2018161223 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
dc.source.none.fl_str_mv |
Brazilian Archives of Biology and Technology v.61 2018 reponame:Brazilian Archives of Biology and Technology instname:Instituto de Tecnologia do Paraná (Tecpar) instacron:TECPAR |
instname_str |
Instituto de Tecnologia do Paraná (Tecpar) |
instacron_str |
TECPAR |
institution |
TECPAR |
reponame_str |
Brazilian Archives of Biology and Technology |
collection |
Brazilian Archives of Biology and Technology |
repository.name.fl_str_mv |
Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar) |
repository.mail.fl_str_mv |
babt@tecpar.br||babt@tecpar.br |
_version_ |
1750318278624935936 |