Viability in the production of a drug extracted from Ananas comosus by a flat membrane system

Detalhes bibliográficos
Autor(a) principal: Lopes,Francisco Luiz Gumes
Data de Publicação: 2012
Outros Autores: Sbruzzi,Dalva, Barros,Kleber Vanio Gomes, Ferreira,Juliana Ferrari, Santana,José Carlos Curvelo, Souza,Roberto Rodrigues de, Tambourgi,Elias Basile
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132012000300018
Resumo: The aim of this work was to study the production of e bromelain from the Ananas comosus L. Merril, by determining the process conditions using flat membranes. The production system modeling generated a hyperbolical curve and the optimization by response surfaces showed an influence of the transmembrane pressure higher than the pH influence. The cost of the production of bromelain from A. comosus was estimated 9 to 13 times lower than Sigma's retail sales price and 6.5 to 8.5 times lower than when this enzyme was obtained through a liquid-liquid extraction, which showed the economical feasibility of the process.
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spelling Viability in the production of a drug extracted from Ananas comosus by a flat membrane systemAnanas comosusbromelainflat membraneproduction costoptimizationThe aim of this work was to study the production of e bromelain from the Ananas comosus L. Merril, by determining the process conditions using flat membranes. The production system modeling generated a hyperbolical curve and the optimization by response surfaces showed an influence of the transmembrane pressure higher than the pH influence. The cost of the production of bromelain from A. comosus was estimated 9 to 13 times lower than Sigma's retail sales price and 6.5 to 8.5 times lower than when this enzyme was obtained through a liquid-liquid extraction, which showed the economical feasibility of the process.Instituto de Tecnologia do Paraná - Tecpar2012-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132012000300018Brazilian Archives of Biology and Technology v.55 n.3 2012reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132012000300018info:eu-repo/semantics/openAccessLopes,Francisco Luiz GumesSbruzzi,DalvaBarros,Kleber Vanio GomesFerreira,Juliana FerrariSantana,José Carlos CurveloSouza,Roberto Rodrigues deTambourgi,Elias Basileeng2012-07-03T00:00:00Zoai:scielo:S1516-89132012000300018Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2012-07-03T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Viability in the production of a drug extracted from Ananas comosus by a flat membrane system
title Viability in the production of a drug extracted from Ananas comosus by a flat membrane system
spellingShingle Viability in the production of a drug extracted from Ananas comosus by a flat membrane system
Lopes,Francisco Luiz Gumes
Ananas comosus
bromelain
flat membrane
production cost
optimization
title_short Viability in the production of a drug extracted from Ananas comosus by a flat membrane system
title_full Viability in the production of a drug extracted from Ananas comosus by a flat membrane system
title_fullStr Viability in the production of a drug extracted from Ananas comosus by a flat membrane system
title_full_unstemmed Viability in the production of a drug extracted from Ananas comosus by a flat membrane system
title_sort Viability in the production of a drug extracted from Ananas comosus by a flat membrane system
author Lopes,Francisco Luiz Gumes
author_facet Lopes,Francisco Luiz Gumes
Sbruzzi,Dalva
Barros,Kleber Vanio Gomes
Ferreira,Juliana Ferrari
Santana,José Carlos Curvelo
Souza,Roberto Rodrigues de
Tambourgi,Elias Basile
author_role author
author2 Sbruzzi,Dalva
Barros,Kleber Vanio Gomes
Ferreira,Juliana Ferrari
Santana,José Carlos Curvelo
Souza,Roberto Rodrigues de
Tambourgi,Elias Basile
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Lopes,Francisco Luiz Gumes
Sbruzzi,Dalva
Barros,Kleber Vanio Gomes
Ferreira,Juliana Ferrari
Santana,José Carlos Curvelo
Souza,Roberto Rodrigues de
Tambourgi,Elias Basile
dc.subject.por.fl_str_mv Ananas comosus
bromelain
flat membrane
production cost
optimization
topic Ananas comosus
bromelain
flat membrane
production cost
optimization
description The aim of this work was to study the production of e bromelain from the Ananas comosus L. Merril, by determining the process conditions using flat membranes. The production system modeling generated a hyperbolical curve and the optimization by response surfaces showed an influence of the transmembrane pressure higher than the pH influence. The cost of the production of bromelain from A. comosus was estimated 9 to 13 times lower than Sigma's retail sales price and 6.5 to 8.5 times lower than when this enzyme was obtained through a liquid-liquid extraction, which showed the economical feasibility of the process.
publishDate 2012
dc.date.none.fl_str_mv 2012-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132012000300018
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132012000300018
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132012000300018
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.55 n.3 2012
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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