Modelagem computacional de sistemas biológicos

Detalhes bibliográficos
Autor(a) principal: Galvão, Viviane Matos
Data de Publicação: 2009
Tipo de documento: Tese
Idioma: por
Título da fonte: Biblioteca Digital de Teses e Dissertações da UEFS
Texto Completo: http://tede2.uefs.br:8080/handle/tede/1224
Resumo: In this work, we develope computational models based on multi-agents, regular lattice and complex networks to reproduce biological systems. The sytems simulated are the network of human cell differentiation, chronic chagasic cardiomyopathy after stem cell transplantation, evolution of Chagas’ disease, and enzyme kinetics of invertase. The characterization of the network of human cell differentiation is vital because it can reveal features of the human embryonic development by using the topological and dynamical properties of the differentiation process. A better understanding of Chagas’ disease is necessary because this illness is still incurable and affects millions of people worldwide. The computational modelling of enzyme kinetics of invertase is important because it can describe complex chemical process.
id UEFS_f83fb3d45e1d70f34c32c5a94149a1a7
oai_identifier_str oai:tede2.uefs.br:8080:tede/1224
network_acronym_str UEFS
network_name_str Biblioteca Digital de Teses e Dissertações da UEFS
repository_id_str
spelling Miranda, José Garcia Vivas5675219951580416110525http://lattes.cnpq.br/5320252621856054Galvão, Viviane Matos2021-03-15T23:23:53Z2009-07-13GALVÃO, Viviane Matos. Modelagem computacional de sistemas biológicos. 2009. 144 f. Tese (Doutorado Acadêmico em Biotecnologia)- Universidade Estadual de Feira de Santana, Feira de Santana, 2009.http://tede2.uefs.br:8080/handle/tede/1224In this work, we develope computational models based on multi-agents, regular lattice and complex networks to reproduce biological systems. The sytems simulated are the network of human cell differentiation, chronic chagasic cardiomyopathy after stem cell transplantation, evolution of Chagas’ disease, and enzyme kinetics of invertase. The characterization of the network of human cell differentiation is vital because it can reveal features of the human embryonic development by using the topological and dynamical properties of the differentiation process. A better understanding of Chagas’ disease is necessary because this illness is still incurable and affects millions of people worldwide. The computational modelling of enzyme kinetics of invertase is important because it can describe complex chemical process.Neste trabalho desenvolvemos modelos computacionais basedos em multi-agentes, redes regulares e redes complexas para reproduzir sistemas biológicos. Os sistemas simulados são a rede de diferenciação celular humana, a cardiomiopatia chagásica crônica depois do trasplante de célulastronco, a evolução da doença de Chagas e a cinética enzimática da invertase. A caracterização da rede de diferenciação celular humana é vital porque ela pode revelar as características do desenvolvimento embrionário humano usando as propriedades dinâmicas e topológicas do processo de diferenciação. Um melhor entendimento da doença de Chagas é necessário porque esta enfermidade é ainda incurável e afeta milhões de pessoas em todo o mundo. A modelagem computacional da cinética enzimática da invertase é importante porque ela pode descrever processos químicos complexos.Submitted by Ricardo Cedraz Duque Moliterno (ricardo.moliterno@uefs.br) on 2021-03-15T23:23:53Z No. of bitstreams: 1 TeseVivianeMatosGalvao.pdf: 1690169 bytes, checksum: e1d4eb77dbd42a065fae068d86b25cc8 (MD5)Made available in DSpace on 2021-03-15T23:23:53Z (GMT). No. of bitstreams: 1 TeseVivianeMatosGalvao.pdf: 1690169 bytes, checksum: e1d4eb77dbd42a065fae068d86b25cc8 (MD5) Previous issue date: 2009-07-13Fundação de Amparo à Pesquisa do Estado da Bahia - FAPEBapplication/pdfporUniversidade Estadual de Feira de SantanaDoutorado Acadêmico em BiotecnologiaUEFSBrasilDEPARTAMENTO DE CIÊNCIAS BIOLÓGICASRede de diferenciação celular humanaDoença de ChagasCélulas-troncoCinética enzimática da invertaseMulti-agentesRedes complexasNetwork of human cell differentiationChagas’ diseaseStem cellEnzymatic kinetics of invertaseMulti-agentsComplex NetworksCIENCIAS BIOLOGICASCIENCIAS BIOLOGICAS::BIOLOGIA GERALModelagem computacional de sistemas biológicosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesis-68152692297897915436006006006006005026123383450589282-3439178843068202161-1634559385931244697-8233071094704392586info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UEFSinstname:Universidade Estadual de Feira de Santana (UEFS)instacron:UEFSORIGINALTeseVivianeMatosGalvao.pdfTeseVivianeMatosGalvao.pdfapplication/pdf1690169http://tede2.uefs.br:8080/bitstream/tede/1224/2/TeseVivianeMatosGalvao.pdfe1d4eb77dbd42a065fae068d86b25cc8MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82089http://tede2.uefs.br:8080/bitstream/tede/1224/1/license.txt7b5ba3d2445355f386edab96125d42b7MD51tede/12242021-03-15 20:23:53.717oai:tede2.uefs.br:8080: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Biblioteca Digital de Teses e Dissertaçõeshttp://tede2.uefs.br:8080/PUBhttp://tede2.uefs.br:8080/oai/requestbcuefs@uefs.br|| bcref@uefs.br||bcuefs@uefs.bropendoar:2021-03-15T23:23:53Biblioteca Digital de Teses e Dissertações da UEFS - Universidade Estadual de Feira de Santana (UEFS)false
dc.title.por.fl_str_mv Modelagem computacional de sistemas biológicos
title Modelagem computacional de sistemas biológicos
spellingShingle Modelagem computacional de sistemas biológicos
Galvão, Viviane Matos
Rede de diferenciação celular humana
Doença de Chagas
Células-tronco
Cinética enzimática da invertase
Multi-agentes
Redes complexas
Network of human cell differentiation
Chagas’ disease
Stem cell
Enzymatic kinetics of invertase
Multi-agents
Complex Networks
CIENCIAS BIOLOGICAS
CIENCIAS BIOLOGICAS::BIOLOGIA GERAL
title_short Modelagem computacional de sistemas biológicos
title_full Modelagem computacional de sistemas biológicos
title_fullStr Modelagem computacional de sistemas biológicos
title_full_unstemmed Modelagem computacional de sistemas biológicos
title_sort Modelagem computacional de sistemas biológicos
author Galvão, Viviane Matos
author_facet Galvão, Viviane Matos
author_role author
dc.contributor.advisor1.fl_str_mv Miranda, José Garcia Vivas
dc.contributor.advisor1ID.fl_str_mv 56752199515
dc.contributor.authorID.fl_str_mv 80416110525
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/5320252621856054
dc.contributor.author.fl_str_mv Galvão, Viviane Matos
contributor_str_mv Miranda, José Garcia Vivas
dc.subject.por.fl_str_mv Rede de diferenciação celular humana
Doença de Chagas
Células-tronco
Cinética enzimática da invertase
Multi-agentes
Redes complexas
topic Rede de diferenciação celular humana
Doença de Chagas
Células-tronco
Cinética enzimática da invertase
Multi-agentes
Redes complexas
Network of human cell differentiation
Chagas’ disease
Stem cell
Enzymatic kinetics of invertase
Multi-agents
Complex Networks
CIENCIAS BIOLOGICAS
CIENCIAS BIOLOGICAS::BIOLOGIA GERAL
dc.subject.eng.fl_str_mv Network of human cell differentiation
Chagas’ disease
Stem cell
Enzymatic kinetics of invertase
Multi-agents
Complex Networks
dc.subject.cnpq.fl_str_mv CIENCIAS BIOLOGICAS
CIENCIAS BIOLOGICAS::BIOLOGIA GERAL
description In this work, we develope computational models based on multi-agents, regular lattice and complex networks to reproduce biological systems. The sytems simulated are the network of human cell differentiation, chronic chagasic cardiomyopathy after stem cell transplantation, evolution of Chagas’ disease, and enzyme kinetics of invertase. The characterization of the network of human cell differentiation is vital because it can reveal features of the human embryonic development by using the topological and dynamical properties of the differentiation process. A better understanding of Chagas’ disease is necessary because this illness is still incurable and affects millions of people worldwide. The computational modelling of enzyme kinetics of invertase is important because it can describe complex chemical process.
publishDate 2009
dc.date.issued.fl_str_mv 2009-07-13
dc.date.accessioned.fl_str_mv 2021-03-15T23:23:53Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/doctoralThesis
format doctoralThesis
status_str publishedVersion
dc.identifier.citation.fl_str_mv GALVÃO, Viviane Matos. Modelagem computacional de sistemas biológicos. 2009. 144 f. Tese (Doutorado Acadêmico em Biotecnologia)- Universidade Estadual de Feira de Santana, Feira de Santana, 2009.
dc.identifier.uri.fl_str_mv http://tede2.uefs.br:8080/handle/tede/1224
identifier_str_mv GALVÃO, Viviane Matos. Modelagem computacional de sistemas biológicos. 2009. 144 f. Tese (Doutorado Acadêmico em Biotecnologia)- Universidade Estadual de Feira de Santana, Feira de Santana, 2009.
url http://tede2.uefs.br:8080/handle/tede/1224
dc.language.iso.fl_str_mv por
language por
dc.relation.program.fl_str_mv -6815269229789791543
dc.relation.confidence.fl_str_mv 600
600
600
600
600
dc.relation.department.fl_str_mv 5026123383450589282
dc.relation.cnpq.fl_str_mv -3439178843068202161
-1634559385931244697
dc.relation.sponsorship.fl_str_mv -8233071094704392586
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Estadual de Feira de Santana
dc.publisher.program.fl_str_mv Doutorado Acadêmico em Biotecnologia
dc.publisher.initials.fl_str_mv UEFS
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv DEPARTAMENTO DE CIÊNCIAS BIOLÓGICAS
publisher.none.fl_str_mv Universidade Estadual de Feira de Santana
dc.source.none.fl_str_mv reponame:Biblioteca Digital de Teses e Dissertações da UEFS
instname:Universidade Estadual de Feira de Santana (UEFS)
instacron:UEFS
instname_str Universidade Estadual de Feira de Santana (UEFS)
instacron_str UEFS
institution UEFS
reponame_str Biblioteca Digital de Teses e Dissertações da UEFS
collection Biblioteca Digital de Teses e Dissertações da UEFS
bitstream.url.fl_str_mv http://tede2.uefs.br:8080/bitstream/tede/1224/2/TeseVivianeMatosGalvao.pdf
http://tede2.uefs.br:8080/bitstream/tede/1224/1/license.txt
bitstream.checksum.fl_str_mv e1d4eb77dbd42a065fae068d86b25cc8
7b5ba3d2445355f386edab96125d42b7
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
repository.name.fl_str_mv Biblioteca Digital de Teses e Dissertações da UEFS - Universidade Estadual de Feira de Santana (UEFS)
repository.mail.fl_str_mv bcuefs@uefs.br|| bcref@uefs.br||bcuefs@uefs.br
_version_ 1809288782030045184

Registros relacionados