Evaluation of in vitro biological properties of Senna occidentalis (L.) Link
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Acta Scientiarum Biological Sciences |
Texto Completo: | http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/22525 |
Resumo: | Senna species have been widely used by American, African and Indian ethic groups mainly in the treatment of feebleness, constipation, liver disorders and skin infections. Senna occidentalis (L.) Link is a perennial shrub native to South America and indigenous to tropical regions throughout the world. Current study evaluated the antimicrobial activity of aqueous and hydroalcoholic extracts from S. occidentalis prepared from different parts of the plant. Antimicrobial activity was assessed against standard pharmaceutical microorganisms by spectrophotometry and microdilution technique. Escherichia coli was sensitive only to compounds extracted from seeds which may be proteinaceous. A broader antimicrobial spectrum was demonstrated by the hydroalcoholic extract of seeds, mostly against Pseudomonas aeruginosa. The in vitro toxicity using mouse fibroblasts indicated that the extract might be a biocompatible ingredient for topical formulations, while the hydroalcoholic extract of aerial parts demonstrated to be potentially cytotoxic. |
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Evaluation of in vitro biological properties of Senna occidentalis (L.) LinkCassia occidentalisLeguminosaetraditional medicineantibacterialantifungalfibroblastsEtnofarmacologiaSenna species have been widely used by American, African and Indian ethic groups mainly in the treatment of feebleness, constipation, liver disorders and skin infections. Senna occidentalis (L.) Link is a perennial shrub native to South America and indigenous to tropical regions throughout the world. Current study evaluated the antimicrobial activity of aqueous and hydroalcoholic extracts from S. occidentalis prepared from different parts of the plant. Antimicrobial activity was assessed against standard pharmaceutical microorganisms by spectrophotometry and microdilution technique. Escherichia coli was sensitive only to compounds extracted from seeds which may be proteinaceous. A broader antimicrobial spectrum was demonstrated by the hydroalcoholic extract of seeds, mostly against Pseudomonas aeruginosa. The in vitro toxicity using mouse fibroblasts indicated that the extract might be a biocompatible ingredient for topical formulations, while the hydroalcoholic extract of aerial parts demonstrated to be potentially cytotoxic. Universidade Estadual De Maringá2015-03-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAtividade antimicrobiana e citotóxicaapplication/pdfhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/2252510.4025/actascibiolsci.v37i1.22525Acta Scientiarum. Biological Sciences; Vol 37 No 1 (2015); 9-13Acta Scientiarum. Biological Sciences; v. 37 n. 1 (2015); 9-131807-863X1679-9283reponame:Acta Scientiarum Biological Sciencesinstname:Universidade Estadual de Maringá (UEM)instacron:UEMenghttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/22525/pdf_33Lombardo, MárciaKiyota, SumikaKato, Edna Tomiko MiyakeMathor, Monica BeatrizPinto, Terezinha de Jesus AndreoliKaneko, Telma Maryinfo:eu-repo/semantics/openAccess2015-03-10T09:15:09Zoai:periodicos.uem.br/ojs:article/22525Revistahttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSciPUBhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/oai||actabiol@uem.br1807-863X1679-9283opendoar:2015-03-10T09:15:09Acta Scientiarum Biological Sciences - Universidade Estadual de Maringá (UEM)false |
dc.title.none.fl_str_mv |
Evaluation of in vitro biological properties of Senna occidentalis (L.) Link |
title |
Evaluation of in vitro biological properties of Senna occidentalis (L.) Link |
spellingShingle |
Evaluation of in vitro biological properties of Senna occidentalis (L.) Link Lombardo, Márcia Cassia occidentalis Leguminosae traditional medicine antibacterial antifungal fibroblasts Etnofarmacologia |
title_short |
Evaluation of in vitro biological properties of Senna occidentalis (L.) Link |
title_full |
Evaluation of in vitro biological properties of Senna occidentalis (L.) Link |
title_fullStr |
Evaluation of in vitro biological properties of Senna occidentalis (L.) Link |
title_full_unstemmed |
Evaluation of in vitro biological properties of Senna occidentalis (L.) Link |
title_sort |
Evaluation of in vitro biological properties of Senna occidentalis (L.) Link |
author |
Lombardo, Márcia |
author_facet |
Lombardo, Márcia Kiyota, Sumika Kato, Edna Tomiko Miyake Mathor, Monica Beatriz Pinto, Terezinha de Jesus Andreoli Kaneko, Telma Mary |
author_role |
author |
author2 |
Kiyota, Sumika Kato, Edna Tomiko Miyake Mathor, Monica Beatriz Pinto, Terezinha de Jesus Andreoli Kaneko, Telma Mary |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Lombardo, Márcia Kiyota, Sumika Kato, Edna Tomiko Miyake Mathor, Monica Beatriz Pinto, Terezinha de Jesus Andreoli Kaneko, Telma Mary |
dc.subject.por.fl_str_mv |
Cassia occidentalis Leguminosae traditional medicine antibacterial antifungal fibroblasts Etnofarmacologia |
topic |
Cassia occidentalis Leguminosae traditional medicine antibacterial antifungal fibroblasts Etnofarmacologia |
description |
Senna species have been widely used by American, African and Indian ethic groups mainly in the treatment of feebleness, constipation, liver disorders and skin infections. Senna occidentalis (L.) Link is a perennial shrub native to South America and indigenous to tropical regions throughout the world. Current study evaluated the antimicrobial activity of aqueous and hydroalcoholic extracts from S. occidentalis prepared from different parts of the plant. Antimicrobial activity was assessed against standard pharmaceutical microorganisms by spectrophotometry and microdilution technique. Escherichia coli was sensitive only to compounds extracted from seeds which may be proteinaceous. A broader antimicrobial spectrum was demonstrated by the hydroalcoholic extract of seeds, mostly against Pseudomonas aeruginosa. The in vitro toxicity using mouse fibroblasts indicated that the extract might be a biocompatible ingredient for topical formulations, while the hydroalcoholic extract of aerial parts demonstrated to be potentially cytotoxic. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-03-10 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Atividade antimicrobiana e citotóxica |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/22525 10.4025/actascibiolsci.v37i1.22525 |
url |
http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/22525 |
identifier_str_mv |
10.4025/actascibiolsci.v37i1.22525 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/22525/pdf_33 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Estadual De Maringá |
publisher.none.fl_str_mv |
Universidade Estadual De Maringá |
dc.source.none.fl_str_mv |
Acta Scientiarum. Biological Sciences; Vol 37 No 1 (2015); 9-13 Acta Scientiarum. Biological Sciences; v. 37 n. 1 (2015); 9-13 1807-863X 1679-9283 reponame:Acta Scientiarum Biological Sciences instname:Universidade Estadual de Maringá (UEM) instacron:UEM |
instname_str |
Universidade Estadual de Maringá (UEM) |
instacron_str |
UEM |
institution |
UEM |
reponame_str |
Acta Scientiarum Biological Sciences |
collection |
Acta Scientiarum Biological Sciences |
repository.name.fl_str_mv |
Acta Scientiarum Biological Sciences - Universidade Estadual de Maringá (UEM) |
repository.mail.fl_str_mv |
||actabiol@uem.br |
_version_ |
1799317396000866304 |