Comparison of inflammatory biomarkers between diabetic and non-diabetic patients with unstable angina

Detalhes bibliográficos
Autor(a) principal: Huoya, Marçal de Oliveira
Data de Publicação: 2009
Outros Autores: Penalva, Rafaela Andrade, Alves, Sílber Rodrigues, Feitosa, Gílson Soares, Gadelha, Sandra Rocha, Ladeia, Ana Marice Teixeira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/13719
Resumo: p. 269-274
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spelling Huoya, Marçal de OliveiraPenalva, Rafaela AndradeAlves, Sílber RodriguesFeitosa, Gílson SoaresGadelha, Sandra RochaLadeia, Ana Marice TeixeiraHuoya, Marçal de OliveiraPenalva, Rafaela AndradeAlves, Sílber RodriguesFeitosa, Gílson SoaresGadelha, Sandra RochaLadeia, Ana Marice Teixeira2013-11-18T21:13:02Z2013-11-18T21:13:02Z20090066-782Xhttp://repositorio.ufba.br/ri/handle/ri/13719v. 92, n. 4p. 269-274Background: Studies comparing inflammatory activity between diabetic and non diabetic individuals with acute coronary syndrome are scarce, and none including only patients with unstable angina (UA) has been published to date. Objective: We compared serum C-reactive protein (CRP), and interleukin-6(IL-6) between diabetic and non-diabetic patients with unstable angina (UA) to determine if difference in inflammatory activity is responsible for a worse prognosis in diabetic patients. We also evaluated the correlation between inflammatory markers and the metabolic profile in diabetic patients and the correlation between inflammatory response and in-hospital outcomes: death, acute myocardial infarction, congestive heart failure, and length of stay in hospital. Methods: A prospective cohort study of 90 consecutive patients admitted to a chest pain unit with UA and divided into two groups, diabetic and non-diabetic. Serum CRP, IL-6, metabolic profile and leukocyte count were measured at hospital arrival. Results: Forty-two patients (47%) were diabetic (age 62±9) vs. 48 (53%) non diabetic (age 63±12). No differences between median C-reactive protein (1.78 vs. 2.23mg/l,p=0.74) and interleukin-6 (0 vs. 0pg/ml,p=0.31) were found between the two groups. There was a positive correlation between CRP and total cholesterol (rs = 0.21,p = 0.05), CRP and LDL-cholesterol (rs=0.22,p=0.04) and between CRP and leukocyte count (rs = 0.32, p = 0.02) in both groups. No associations were found between inflammatory markers and in-hospital outcomes. Conclusion: We found no difference in inflammatory activity between diabetic and non diabetic patients with UA, suggesting that this clinical condition may result in balanced inflammatory activity between the two groups and increase acute-phase proteins independently of metabolic state.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-10-15T14:58:13Z No. of bitstreams: 1 en_v92n4a06.pdf: 369689 bytes, checksum: f38dcddfd847d43f6c3ebf3c72ba504e (MD5)Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2013-11-18T21:13:02Z (GMT) No. of bitstreams: 1 en_v92n4a06.pdf: 369689 bytes, checksum: f38dcddfd847d43f6c3ebf3c72ba504e (MD5)Made available in DSpace on 2013-11-18T21:13:02Z (GMT). No. of bitstreams: 1 en_v92n4a06.pdf: 369689 bytes, checksum: f38dcddfd847d43f6c3ebf3c72ba504e (MD5) Previous issue date: 2009http://dx.doi.org/10.1590/S0066-782X2009000400006reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAAngina pectorisAtherosclerosis / complicationsDiabetes mellitusInflammation / complicationsComparison of inflammatory biomarkers between diabetic and non-diabetic patients with unstable anginaArquivos Brasileiros de Cardiologiainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleenginfo:eu-repo/semantics/openAccessORIGINALen_v92n4a06.pdfen_v92n4a06.pdfapplication/pdf369689https://repositorio.ufba.br/bitstream/ri/13719/1/en_v92n4a06.pdff38dcddfd847d43f6c3ebf3c72ba504eMD51LICENSElicense.txtlicense.txttext/plain1365https://repositorio.ufba.br/bitstream/ri/13719/2/license.txt5371a150bdc863f78dcf39281543bd86MD52TEXTen_v92n4a06.pdf.txten_v92n4a06.pdf.txtExtracted texttext/plain33009https://repositorio.ufba.br/bitstream/ri/13719/3/en_v92n4a06.pdf.txt148c1265caa69743ce2b069dc8dafb67MD53ri/137192022-07-05 14:03:21.333oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:21Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Comparison of inflammatory biomarkers between diabetic and non-diabetic patients with unstable angina
dc.title.alternative.pt_BR.fl_str_mv Arquivos Brasileiros de Cardiologia
title Comparison of inflammatory biomarkers between diabetic and non-diabetic patients with unstable angina
spellingShingle Comparison of inflammatory biomarkers between diabetic and non-diabetic patients with unstable angina
Huoya, Marçal de Oliveira
Angina pectoris
Atherosclerosis / complications
Diabetes mellitus
Inflammation / complications
title_short Comparison of inflammatory biomarkers between diabetic and non-diabetic patients with unstable angina
title_full Comparison of inflammatory biomarkers between diabetic and non-diabetic patients with unstable angina
title_fullStr Comparison of inflammatory biomarkers between diabetic and non-diabetic patients with unstable angina
title_full_unstemmed Comparison of inflammatory biomarkers between diabetic and non-diabetic patients with unstable angina
title_sort Comparison of inflammatory biomarkers between diabetic and non-diabetic patients with unstable angina
author Huoya, Marçal de Oliveira
author_facet Huoya, Marçal de Oliveira
Penalva, Rafaela Andrade
Alves, Sílber Rodrigues
Feitosa, Gílson Soares
Gadelha, Sandra Rocha
Ladeia, Ana Marice Teixeira
author_role author
author2 Penalva, Rafaela Andrade
Alves, Sílber Rodrigues
Feitosa, Gílson Soares
Gadelha, Sandra Rocha
Ladeia, Ana Marice Teixeira
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Huoya, Marçal de Oliveira
Penalva, Rafaela Andrade
Alves, Sílber Rodrigues
Feitosa, Gílson Soares
Gadelha, Sandra Rocha
Ladeia, Ana Marice Teixeira
Huoya, Marçal de Oliveira
Penalva, Rafaela Andrade
Alves, Sílber Rodrigues
Feitosa, Gílson Soares
Gadelha, Sandra Rocha
Ladeia, Ana Marice Teixeira
dc.subject.por.fl_str_mv Angina pectoris
Atherosclerosis / complications
Diabetes mellitus
Inflammation / complications
topic Angina pectoris
Atherosclerosis / complications
Diabetes mellitus
Inflammation / complications
description p. 269-274
publishDate 2009
dc.date.issued.fl_str_mv 2009
dc.date.accessioned.fl_str_mv 2013-11-18T21:13:02Z
dc.date.available.fl_str_mv 2013-11-18T21:13:02Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/13719
dc.identifier.issn.none.fl_str_mv 0066-782X
dc.identifier.number.pt_BR.fl_str_mv v. 92, n. 4
identifier_str_mv 0066-782X
v. 92, n. 4
url http://repositorio.ufba.br/ri/handle/ri/13719
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1590/S0066-782X2009000400006
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
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reponame_str Repositório Institucional da UFBA
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