Oral health profile in patients infected with HTLV-1: Clinical findings, proviral load, and molecular analysis from HTLV-1 in saliva
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2012 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFBA |
| Texto Completo: | http://repositorio.ufba.br/ri/handle/ri/16601 |
Resumo: | Texto completo: acesso restrito. p. 1428–1436 |
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Lins, LilianeCarvalho, Victor José Uchoa deRego, Filipe Ferreira de AlmeidaAzevedo, RocheleKashima, SimoneGallazi, Viviana Nilla OlavarriaXavier, Márcia TostaCastro, Bernardo GalvãoAlcântara, Luiz Carlos JúniorLins, LilianeCarvalho, Victor José Uchoa deRego, Filipe Ferreira de AlmeidaAzevedo, RocheleKashima, SimoneGallazi, Viviana Nilla OlavarriaXavier, Márcia TostaCastro, Bernardo GalvãoAlcântara, Luiz Carlos Júnior2014-11-14T13:00:07Z20120146-6615http://repositorio.ufba.br/ri/handle/ri/16601v. 84, n. 9Texto completo: acesso restrito. p. 1428–1436Human T-lymphotropic virus type 1 (HTLV-1) is associated with adult T-cell leukemia (ATL) and HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) and has also been implicated in several disorders, including periodontal disease. The proviral load is an important biological marker for understanding HTLV-1 pathogenesis and elucidating whether or not the virus is related to the clinical manifestation of the disease. This study describes the oral health profile of HTLV-1 carriers and HAM/TSP patients in order to investigate the association between the proviral load in saliva and the severity of the periodontal disease and to examine virus intra-host variations from peripheral blood mononuclear cells and saliva cells. It is a cross-sectional analytical study of 90 individuals carried out from November 2006 to May 2008. Of the patients, 60 were HTLV-1 positive and 30 were negative. Individuals from the HTLV-1 positive and negative groups had similar mean age and social-economic status. Data were analyzed using two available statistical software packages, STATA 8.0 and SPSS 11.0 to conduct frequency analysis. Differences of P < 0.05 were considered statistically significant. HTLV-1 patients had poorer oral health status when compared to seronegative individuals. A weak positive correlation between blood and saliva proviral loads was observed. The mean values of proviral load in blood and saliva in patients with HAM/TSP was greater than those in HTLV-1 carriers. The HTLV-1 molecular analysis from PBMC and saliva specimens suggests that HTLV-1 in saliva is due to lymphocyte infiltration from peripheral blood. A direct relationship between the proviral load in saliva and oral manifestations was observed.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-07-15T13:06:44Z No. of bitstreams: 1 Liliane Lins.pdf: 123808 bytes, checksum: 5d13c0001a41d53221a8388c058dea62 (MD5)Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2014-11-14T13:00:06Z (GMT) No. of bitstreams: 1 Liliane Lins.pdf: 123808 bytes, checksum: 5d13c0001a41d53221a8388c058dea62 (MD5)Made available in DSpace on 2014-11-14T13:00:07Z (GMT). No. of bitstreams: 1 Liliane Lins.pdf: 123808 bytes, checksum: 5d13c0001a41d53221a8388c058dea62 (MD5) Previous issue date: 2012http://dx.doi.org/ 10.1002/jmv.23327reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAOral HealthSalivaHTLV-1Oral health profile in patients infected with HTLV-1: Clinical findings, proviral load, and molecular analysis from HTLV-1 in salivaJournal of Medical Virologyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALLiliane Lins.pdfLiliane Lins.pdfapplication/pdf123808https://repositorio.ufba.br/bitstream/ri/16601/1/Liliane%20Lins.pdf5d13c0001a41d53221a8388c058dea62MD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/16601/2/license.txt0d4b811ef71182510d2015daa7c8a900MD52TEXTLiliane Lins.pdf.txtLiliane Lins.pdf.txtExtracted texttext/plain41126https://repositorio.ufba.br/bitstream/ri/16601/3/Liliane%20Lins.pdf.txt0a2b00013fddfc7661e21a46022489dfMD53ri/166012022-07-05 14:03:31.835oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:31Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
| dc.title.pt_BR.fl_str_mv |
Oral health profile in patients infected with HTLV-1: Clinical findings, proviral load, and molecular analysis from HTLV-1 in saliva |
| dc.title.alternative.pt_BR.fl_str_mv |
Journal of Medical Virology |
| title |
Oral health profile in patients infected with HTLV-1: Clinical findings, proviral load, and molecular analysis from HTLV-1 in saliva |
| spellingShingle |
Oral health profile in patients infected with HTLV-1: Clinical findings, proviral load, and molecular analysis from HTLV-1 in saliva Lins, Liliane Oral Health Saliva HTLV-1 |
| title_short |
Oral health profile in patients infected with HTLV-1: Clinical findings, proviral load, and molecular analysis from HTLV-1 in saliva |
| title_full |
Oral health profile in patients infected with HTLV-1: Clinical findings, proviral load, and molecular analysis from HTLV-1 in saliva |
| title_fullStr |
Oral health profile in patients infected with HTLV-1: Clinical findings, proviral load, and molecular analysis from HTLV-1 in saliva |
| title_full_unstemmed |
Oral health profile in patients infected with HTLV-1: Clinical findings, proviral load, and molecular analysis from HTLV-1 in saliva |
| title_sort |
Oral health profile in patients infected with HTLV-1: Clinical findings, proviral load, and molecular analysis from HTLV-1 in saliva |
| author |
Lins, Liliane |
| author_facet |
Lins, Liliane Carvalho, Victor José Uchoa de Rego, Filipe Ferreira de Almeida Azevedo, Rochele Kashima, Simone Gallazi, Viviana Nilla Olavarria Xavier, Márcia Tosta Castro, Bernardo Galvão Alcântara, Luiz Carlos Júnior |
| author_role |
author |
| author2 |
Carvalho, Victor José Uchoa de Rego, Filipe Ferreira de Almeida Azevedo, Rochele Kashima, Simone Gallazi, Viviana Nilla Olavarria Xavier, Márcia Tosta Castro, Bernardo Galvão Alcântara, Luiz Carlos Júnior |
| author2_role |
author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Lins, Liliane Carvalho, Victor José Uchoa de Rego, Filipe Ferreira de Almeida Azevedo, Rochele Kashima, Simone Gallazi, Viviana Nilla Olavarria Xavier, Márcia Tosta Castro, Bernardo Galvão Alcântara, Luiz Carlos Júnior Lins, Liliane Carvalho, Victor José Uchoa de Rego, Filipe Ferreira de Almeida Azevedo, Rochele Kashima, Simone Gallazi, Viviana Nilla Olavarria Xavier, Márcia Tosta Castro, Bernardo Galvão Alcântara, Luiz Carlos Júnior |
| dc.subject.por.fl_str_mv |
Oral Health Saliva HTLV-1 |
| topic |
Oral Health Saliva HTLV-1 |
| description |
Texto completo: acesso restrito. p. 1428–1436 |
| publishDate |
2012 |
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2012 |
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2014-11-14T13:00:07Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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0146-6615 |
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v. 84, n. 9 |
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0146-6615 v. 84, n. 9 |
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reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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