Is cerebellar volume related to bipolar disorder?
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2011 |
| Outros Autores: | , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFBA |
| Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/5436 |
Resumo: | texto completo: acesso restrito. p. 305–309. |
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Quarantini, Lucas de CastroRocha, Marlos Fernando VasconcelosOliveira, Irismar Reis deScippa, Ângela Marisa de Aquino MirandaFernandes, Fabiana NeryJackowski, Andrea ParolinBaldaçara, Leonardo RodrigoRocha, G. G. L.Guimarães, J. L.Araújo, C.Quarantini, Lucas de CastroRocha, Marlos Fernando VasconcelosOliveira, Irismar Reis deScippa, Ângela Marisa de Aquino MirandaFernandes, Fabiana NeryJackowski, Andrea ParolinBaldaçara, Leonardo RodrigoRocha, G. G. L.Guimarães, J. L.Araújo, C.2012-02-24T13:21:37Z20111573-2517http://www.repositorio.ufba.br/ri/handle/ri/5436v. 135.texto completo: acesso restrito. p. 305–309.The findings of cerebellar abnormalities in bipolar disorder (BD) are especially intriguing given the link between the cerebellum emotional and behavioral regulation. The purpose of this study was to evaluate cerebellar volume in patients with euthymic BD type I compared to controls. Moreover, we investigated the possible relationship between cerebellar volume and suicidal behavior. Methods: Forty-patients with euthymic BD type I, 20 with and 20 without history of suicide attempt, and 22 healthy controls underwent an MRI scan. The participants were interviewed using the Structured Clinical Interview with the DSM-IV axis I (SCID-I), the Hamilton Depression Rating Scale (HDRS), the Young Mania Rating Scale (YMRS) and the Barratt Impulsiveness Scale (BIS-11). Results: Groups were age, gender and years of schooling-matched. The left cerebellum (p=0.02), right cerebellum (p=0.02) and vermis (pb0.01) were significantly smaller in the BD group; however, there were no volumetric differences between the BD subjects with and without suicidal attempt. There was no correlation between cerebellar measurements and clinical variables. Limitations: The main strength is that our sample consisted of patients with euthymic BD type I without any comorbidities, however, these results cannot establish causality as the crosssectional nature of the study. Conclusions: Our findings suggest that the reduction in cerebellar volumes observed in BD type I might be a trait-related characteristic of this disorder. Additional studies with larger samples and subtypes of this heterogeneous disorder are warranted to determine the possible specificity of this cerebellar finding.Submitted by Ana Valéria de Jesus Moura (anavaleria_131@hotmail.com) on 2012-02-24T13:21:37Z No. of bitstreams: 1 Is cerebellar volume related to bipolar disorder_.pdf: 113064 bytes, checksum: 16d59e36f10e32d718c4128825637f28 (MD5)Made available in DSpace on 2012-02-24T13:21:37Z (GMT). No. of bitstreams: 1 Is cerebellar volume related to bipolar disorder_.pdf: 113064 bytes, checksum: 16d59e36f10e32d718c4128825637f28 (MD5) Previous issue date: 2011doi:10.1016/j.jad.2011.06.059reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBABipolar disorderCerebellumMagnetic Resonance ImagingMood disordersNeurobiologyIs cerebellar volume related to bipolar disorder?Journal of Affective Disordersinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessORIGINALIs cerebellar volume related to bipolar disorder_.pdfIs cerebellar volume related to bipolar disorder_.pdfapplication/pdf113064https://repositorio.ufba.br/bitstream/ri/5436/1/Is%20cerebellar%20volume%20related%20to%20bipolar%20disorder_.pdf16d59e36f10e32d718c4128825637f28MD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/5436/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXTIs cerebellar volume related to bipolar disorder_.pdf.txtIs cerebellar volume related to bipolar disorder_.pdf.txtExtracted texttext/plain27792https://repositorio.ufba.br/bitstream/ri/5436/3/Is%20cerebellar%20volume%20related%20to%20bipolar%20disorder_.pdf.txt4c18ebabf46313bf0148b24ff6cde27eMD53ri/54362022-07-05 14:03:20.644oai:repositorio.ufba.br:ri/5436VGVybW8gZGUgTGljZW7vv71hLCBu77+9byBleGNsdXNpdm8sIHBhcmEgbyBkZXDvv71zaXRvIG5vIHJlcG9zaXTvv71yaW8gSW5zdGl0dWNpb25hbCBkYSBVRkJBCgogICAgUGVsbyBwcm9jZXNzbyBkZSBzdWJtaXNz77+9byBkZSBkb2N1bWVudG9zLCBvIGF1dG9yIG91IHNldQpyZXByZXNlbnRhbnRlIGxlZ2FsLCBhbyBhY2VpdGFyIGVzc2UgdGVybW8gZGUgbGljZW7vv71hLCBjb25jZWRlIGFvClJlcG9zaXTvv71yaW8gSW5zdGl0dWNpb25hbCBkYSBVbml2ZXJzaWRhZGUgRmVkZXJhbCBkYSBCYWhpYSBvIGRpcmVpdG8KZGUgbWFudGVyIHVtYSBj77+9cGlhIGVtIHNldSByZXBvc2l077+9cmlvIGNvbSBhIGZpbmFsaWRhZGUsIHByaW1laXJhLCAKZGUgcHJlc2VydmHvv73vv71vLiBFc3NlcyB0ZXJtb3MsIG7vv71vIGV4Y2x1c2l2b3MsIG1hbnTvv71tIG9zIGRpcmVpdG9zIGRlIAphdXRvci9jb3B5cmlnaHQsIG1hcyBlbnRlbmRlIG8gZG9jdW1lbnRvIGNvbW8gcGFydGUgZG8gYWNlcnZvIGludGVsZWN0dWFsIGRlc3NhIFVuaXZlcnNpZGFkZS4gCgogICAgUGFyYSBvcyBkb2N1bWVudG9zIHB1YmxpY2Fkb3MgY29tIHJlcGFzc2UgZGUgZGlyZWl0b3MgZGUgZGlzdHJpYnVp77+977+9bywgZXNzZSB0ZXJtbyBkZSBsaWNlbu+/vWEgZW50ZW5kZSBxdWU6IAoKICAgIE1hbnRlbmRvIG9zICBkaXJlaXRvcyBhdXRvcmFpcywgcmVwYXNzYWRvcyBhIHRlcmNlaXJvcywgZW0gY2FzbyAKZGUgcHVibGljYe+/ve+/vWVzLCBvIHJlcG9zaXTvv71yaW8gcG9kZSByZXN0cmluZ2lyIG8gYWNlc3NvIGFvIHRleHRvIAppbnRlZ3JhbCwgbWFzIGxpYmVyYSBhcyBpbmZvcm1h77+977+9ZXMgc29icmUgbyBkb2N1bWVudG8gKE1ldGFkYWRvcyBkZXNjcml0aXZvcykuCgogRGVzdGEgZm9ybWEsIGF0ZW5kZW5kbyBhb3MgYW5zZWlvcyBkZXNzYSB1bml2ZXJzaWRhZGUgCmVtIG1hbnRlciBzdWEgcHJvZHXvv73vv71vIGNpZW5077+9ZmljYSBjb20gYXMgcmVzdHJp77+977+9ZXMgaW1wb3N0YXMgcGVsb3MgCmVkaXRvcmVzIGRlIHBlcmnvv71kaWNvcy4gCgogICAgUGFyYSBhcyBwdWJsaWNh77+977+9ZXMgZW0gaW5pY2lhdGl2YXMgcXVlIHNlZ3VlbSBhIHBvbO+/vXRpY2EgZGUgCkFjZXNzbyBBYmVydG8sIG9zIGRlcO+/vXNpdG9zIGNvbXB1bHPvv71yaW9zIG5lc3NlIHJlcG9zaXTvv71yaW8gbWFudO+/vW0gCm9zIGRpcmVpdG9zIGF1dG9yYWlzLCBtYXMgbWFudO+/vW0gbyBhY2Vzc28gaXJyZXN0cml0byBhbyBtZXRhZGFkb3MgCmUgdGV4dG8gY29tcGxldG8uIEFzc2ltLCBhIGFjZWl0Ye+/ve+/vW8gZGVzc2UgdGVybW8gbu+/vW8gbmVjZXNzaXRhIGRlIApjb25zZW50aW1lbnRvIHBvciBwYXJ0ZSBkZSBhdXRvcmVzL2RldGVudG9yZXMgZG9zIGRpcmVpdG9zLCBwb3IgCmVzdGFyZW0gZW0gaW5pY2lhdGl2YXMgZGUgYWNlc3NvIGFiZXJ0by4KCiAgICBFbSBhbWJvcyBvIGNhc28sIGVzc2UgdGVybW8gZGUgbGljZW7vv71hLCBwb2RlIHNlciBhY2VpdG8gcGVsbyAKYXV0b3IsIGRldGVudG9yZXMgZGUgZGlyZWl0b3MgZS9vdSB0ZXJjZWlyb3MgYW1wYXJhZG9zIHBlbGEgCnVuaXZlcnNpZGFkZS4gRGV2aWRvIGFvcyBkaWZlcmVudGVzIHByb2Nlc3NvcyBwZWxvIHF1YWwgYSBzdWJtaXNz77+9byAKcG9kZSBvY29ycmVyLCBvIHJlcG9zaXTvv71yaW8gcGVybWl0ZSBhIGFjZWl0Ye+/ve+/vW8gZGEgbGljZW7vv71hIHBvciAKdGVyY2Vpcm9zLCBzb21lbnRlIG5vcyBjYXNvcyBkZSBkb2N1bWVudG9zIHByb2R1emlkb3MgcG9yIGludGVncmFudGVzIApkYSBVRkJBIGUgc3VibWV0aWRvcyBwb3IgcGVzc29hcyBhbXBhcmFkYXMgcG9yIGVzdGEgaW5zdGl0dWnvv73vv71vLgo=Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:20Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
| dc.title.pt_BR.fl_str_mv |
Is cerebellar volume related to bipolar disorder? |
| dc.title.alternative.pt_BR.fl_str_mv |
Journal of Affective Disorders |
| title |
Is cerebellar volume related to bipolar disorder? |
| spellingShingle |
Is cerebellar volume related to bipolar disorder? Quarantini, Lucas de Castro Bipolar disorder Cerebellum Magnetic Resonance Imaging Mood disorders Neurobiology |
| title_short |
Is cerebellar volume related to bipolar disorder? |
| title_full |
Is cerebellar volume related to bipolar disorder? |
| title_fullStr |
Is cerebellar volume related to bipolar disorder? |
| title_full_unstemmed |
Is cerebellar volume related to bipolar disorder? |
| title_sort |
Is cerebellar volume related to bipolar disorder? |
| author |
Quarantini, Lucas de Castro |
| author_facet |
Quarantini, Lucas de Castro Rocha, Marlos Fernando Vasconcelos Oliveira, Irismar Reis de Scippa, Ângela Marisa de Aquino Miranda Fernandes, Fabiana Nery Jackowski, Andrea Parolin Baldaçara, Leonardo Rodrigo Rocha, G. G. L. Guimarães, J. L. Araújo, C. |
| author_role |
author |
| author2 |
Rocha, Marlos Fernando Vasconcelos Oliveira, Irismar Reis de Scippa, Ângela Marisa de Aquino Miranda Fernandes, Fabiana Nery Jackowski, Andrea Parolin Baldaçara, Leonardo Rodrigo Rocha, G. G. L. Guimarães, J. L. Araújo, C. |
| author2_role |
author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Quarantini, Lucas de Castro Rocha, Marlos Fernando Vasconcelos Oliveira, Irismar Reis de Scippa, Ângela Marisa de Aquino Miranda Fernandes, Fabiana Nery Jackowski, Andrea Parolin Baldaçara, Leonardo Rodrigo Rocha, G. G. L. Guimarães, J. L. Araújo, C. Quarantini, Lucas de Castro Rocha, Marlos Fernando Vasconcelos Oliveira, Irismar Reis de Scippa, Ângela Marisa de Aquino Miranda Fernandes, Fabiana Nery Jackowski, Andrea Parolin Baldaçara, Leonardo Rodrigo Rocha, G. G. L. Guimarães, J. L. Araújo, C. |
| dc.subject.por.fl_str_mv |
Bipolar disorder Cerebellum Magnetic Resonance Imaging Mood disorders Neurobiology |
| topic |
Bipolar disorder Cerebellum Magnetic Resonance Imaging Mood disorders Neurobiology |
| description |
texto completo: acesso restrito. p. 305–309. |
| publishDate |
2011 |
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2011 |
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2012-02-24T13:21:37Z |
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info:eu-repo/semantics/publishedVersion |
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1573-2517 |
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v. 135. |
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1573-2517 v. 135. |
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