Partial benefit of anastrozole in the long-term treatment of precocious puberty in McCune-Albright syndrome
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://repositorio.ufba.br/ri/handle/ri/16165 |
Resumo: | Texto completo: acesso restrito. p. 323–325 |
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Alves, Crésio de Aragão DantasSilva, Sheila FerreiraAlves, Crésio de Aragão DantasSilva, Sheila Ferreira2014-09-25T14:59:25Z20120334-018Xhttp://repositorio.ufba.br/ri/handle/ri/16165v. 25, n. 3Texto completo: acesso restrito. p. 323–325We report a long-term follow-up on the use of anastrozole in the treatment of peripheral precocious puberty (PP) in McCune-Albright syndrome (MAS). A girl, age 3 years and 9 months, was diagnosed with MAS due to PP, café-au-lait spots, and polyostotic fibrous dysplasia. Serum estradiol was elevated, and gonadotropins were suppressed. Pelvic ultrasound showed an enlarged uterus and a follicle cyst (13 mm) in the left ovary. Bone scintigraphy showed osteogenic lesions on the skull, humerus, tibia, and acetabulum. Bone age was 3 years and 5 months at the chronological age of 3 years. After 36 months of treatment with anastrozole (1 mg/day), there was suppression of breast growth, normalization of growth velocity and serum estradiol, and disappearance of ovarian cysts. However, there was increase in uterine volume, advancement of bone age, and two episodes of vaginal bleeding (18th and 24th months). This report shows the partial benefit of anastrozole in the treatment of peripheral PP of girls with MAS.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-08-13T15:00:03Z No. of bitstreams: 1 Cresio Alves.pdf: 67217 bytes, checksum: d6f5472f439d9a78a1a9cab7721021aa (MD5)Approved for entry into archive by Delba Rosa (delba@ufba.br) on 2014-09-25T14:59:25Z (GMT) No. of bitstreams: 1 Cresio Alves.pdf: 67217 bytes, checksum: d6f5472f439d9a78a1a9cab7721021aa (MD5)Made available in DSpace on 2014-09-25T14:59:25Z (GMT). No. of bitstreams: 1 Cresio Alves.pdf: 67217 bytes, checksum: d6f5472f439d9a78a1a9cab7721021aa (MD5) Previous issue date: 2012http://dx.doi.org/ 10.1515/jpem-2011-0472reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAAnastrazoleAromatase inhibitorsMcCune-Albright syndromePrecocious pubertyPartial benefit of anastrozole in the long-term treatment of precocious puberty in McCune-Albright syndromeJournal of Pediatric Endocrinology and Metabolisminfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALCresio Alves.pdfCresio Alves.pdfapplication/pdf67217https://repositorio.ufba.br/bitstream/ri/16165/1/Cresio%20Alves.pdfd6f5472f439d9a78a1a9cab7721021aaMD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/16165/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXTCresio Alves.pdf.txtCresio Alves.pdf.txtExtracted texttext/plain16002https://repositorio.ufba.br/bitstream/ri/16165/3/Cresio%20Alves.pdf.txta3f53ff58ce471a7cb6a415ec466d55cMD53ri/161652022-08-08 13:17:27.244oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-08-08T16:17:27Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
Partial benefit of anastrozole in the long-term treatment of precocious puberty in McCune-Albright syndrome |
dc.title.alternative.pt_BR.fl_str_mv |
Journal of Pediatric Endocrinology and Metabolism |
title |
Partial benefit of anastrozole in the long-term treatment of precocious puberty in McCune-Albright syndrome |
spellingShingle |
Partial benefit of anastrozole in the long-term treatment of precocious puberty in McCune-Albright syndrome Alves, Crésio de Aragão Dantas Anastrazole Aromatase inhibitors McCune-Albright syndrome Precocious puberty |
title_short |
Partial benefit of anastrozole in the long-term treatment of precocious puberty in McCune-Albright syndrome |
title_full |
Partial benefit of anastrozole in the long-term treatment of precocious puberty in McCune-Albright syndrome |
title_fullStr |
Partial benefit of anastrozole in the long-term treatment of precocious puberty in McCune-Albright syndrome |
title_full_unstemmed |
Partial benefit of anastrozole in the long-term treatment of precocious puberty in McCune-Albright syndrome |
title_sort |
Partial benefit of anastrozole in the long-term treatment of precocious puberty in McCune-Albright syndrome |
author |
Alves, Crésio de Aragão Dantas |
author_facet |
Alves, Crésio de Aragão Dantas Silva, Sheila Ferreira |
author_role |
author |
author2 |
Silva, Sheila Ferreira |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Alves, Crésio de Aragão Dantas Silva, Sheila Ferreira Alves, Crésio de Aragão Dantas Silva, Sheila Ferreira |
dc.subject.por.fl_str_mv |
Anastrazole Aromatase inhibitors McCune-Albright syndrome Precocious puberty |
topic |
Anastrazole Aromatase inhibitors McCune-Albright syndrome Precocious puberty |
description |
Texto completo: acesso restrito. p. 323–325 |
publishDate |
2012 |
dc.date.issued.fl_str_mv |
2012 |
dc.date.accessioned.fl_str_mv |
2014-09-25T14:59:25Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://repositorio.ufba.br/ri/handle/ri/16165 |
dc.identifier.issn.none.fl_str_mv |
0334-018X |
dc.identifier.number.pt_BR.fl_str_mv |
v. 25, n. 3 |
identifier_str_mv |
0334-018X v. 25, n. 3 |
url |
http://repositorio.ufba.br/ri/handle/ri/16165 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
dc.source.pt_BR.fl_str_mv |
http://dx.doi.org/ 10.1515/jpem-2011-0472 |
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reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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Universidade Federal da Bahia (UFBA) |
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UFBA |
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