Morphological assessment of the behavior of three-dimensional anionic collagen matrices in bone regeneration in rats

Detalhes bibliográficos
Autor(a) principal: Miguel, Fúlvio Borges
Data de Publicação: 2006
Outros Autores: Rosa, Fabiana Paim, Cardoso, Ana Karina Mendes Veloso, Barbosa Júnior, Aryon de Almeida, Marcantonio Junior, Elcio, Goissis, Gilberto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/12435
Resumo: Texto completo: acesso restrito. p.334–339
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spelling Miguel, Fúlvio BorgesRosa, Fabiana PaimCardoso, Ana Karina Mendes VelosoBarbosa Júnior, Aryon de AlmeidaMarcantonio Junior, ElcioGoissis, GilbertoMiguel, Fúlvio BorgesRosa, Fabiana PaimCardoso, Ana Karina Mendes VelosoBarbosa Júnior, Aryon de AlmeidaMarcantonio Junior, ElcioGoissis, Gilberto2013-08-05T09:52:23Z20061552-4973http://www.repositorio.ufba.br/ri/handle/ri/12435v. 78 B n. 2Texto completo: acesso restrito. p.334–339The osteogenic behavior of three-dimensional collagenic and anionic matrices (M3DGA) implanted in critical bone defects of 8 mm diameter was morphologically assessed. The defects were performed in the calvaria of 48 adult male (Wistar) rats, and observed at days 15, 30, and 60. The animals were distributed in four groups of equal number: GA1 (M3DGA with 60 min of cross-linking in glutaraldehyde [GA]); GA2 (M3DGA with 30 min of cross-linking in GA); GA3 (M3DGA with 15 min of cross-linking in GA); and G4 (control group, without any implanted biomaterial). The M3DGAs were biocompatible, with mild and regressive chronic granulomatous inflammation, associated with the degradation of their fibers. Furthermore, tissue neovascularization and neomineralization was noted, with statistically significant differences in these amounts among the groups (GA1, GA2, and GA3) and G4. In G4 neoformation was limited to the edges of the defect as well as interstitial fibrosis. Under the experimental conditions and for the parameters analyzed, the M3DGAs had osteogenic behavior, which was more evident in M3DGA 15 min. © 2006 Wiley Periodicals, Inc.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2013-08-02T15:38:37Z No. of bitstreams: 1 30492_ftp.pdf: 331825 bytes, checksum: 526d8beb858dadae2ae1d7e49c819ef9 (MD5)Approved for entry into archive by Rodrigo Meirelles(rodrigomei@ufba.br) on 2013-08-05T09:52:23Z (GMT) No. of bitstreams: 1 30492_ftp.pdf: 331825 bytes, checksum: 526d8beb858dadae2ae1d7e49c819ef9 (MD5)Made available in DSpace on 2013-08-05T09:52:23Z (GMT). No. of bitstreams: 1 30492_ftp.pdf: 331825 bytes, checksum: 526d8beb858dadae2ae1d7e49c819ef9 (MD5) Previous issue date: 2006http://dx.doi.org/ 10.1002/jbm.b.30492reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBATissue bioengineering;Anionic collagen;Three-dimensional matrix;Bone regenerationCritical size defectMorphological assessment of the behavior of three-dimensional anionic collagen matrices in bone regeneration in ratsJournal of Biomedical Materials Research Part B: Applied Biomaterialsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessORIGINAL30492_ftp.pdf30492_ftp.pdfapplication/pdf331825https://repositorio.ufba.br/bitstream/ri/12435/1/30492_ftp.pdf526d8beb858dadae2ae1d7e49c819ef9MD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/12435/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT30492_ftp.pdf.txt30492_ftp.pdf.txtExtracted texttext/plain23628https://repositorio.ufba.br/bitstream/ri/12435/3/30492_ftp.pdf.txt781d7474a0f49f4acc0ab0a2e50b6070MD53ri/124352022-07-05 14:03:44.672oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:44Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Morphological assessment of the behavior of three-dimensional anionic collagen matrices in bone regeneration in rats
dc.title.alternative.pt_BR.fl_str_mv Journal of Biomedical Materials Research Part B: Applied Biomaterials
title Morphological assessment of the behavior of three-dimensional anionic collagen matrices in bone regeneration in rats
spellingShingle Morphological assessment of the behavior of three-dimensional anionic collagen matrices in bone regeneration in rats
Miguel, Fúlvio Borges
Tissue bioengineering;
Anionic collagen;
Three-dimensional matrix;
Bone regeneration
Critical size defect
title_short Morphological assessment of the behavior of three-dimensional anionic collagen matrices in bone regeneration in rats
title_full Morphological assessment of the behavior of three-dimensional anionic collagen matrices in bone regeneration in rats
title_fullStr Morphological assessment of the behavior of three-dimensional anionic collagen matrices in bone regeneration in rats
title_full_unstemmed Morphological assessment of the behavior of three-dimensional anionic collagen matrices in bone regeneration in rats
title_sort Morphological assessment of the behavior of three-dimensional anionic collagen matrices in bone regeneration in rats
author Miguel, Fúlvio Borges
author_facet Miguel, Fúlvio Borges
Rosa, Fabiana Paim
Cardoso, Ana Karina Mendes Veloso
Barbosa Júnior, Aryon de Almeida
Marcantonio Junior, Elcio
Goissis, Gilberto
author_role author
author2 Rosa, Fabiana Paim
Cardoso, Ana Karina Mendes Veloso
Barbosa Júnior, Aryon de Almeida
Marcantonio Junior, Elcio
Goissis, Gilberto
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Miguel, Fúlvio Borges
Rosa, Fabiana Paim
Cardoso, Ana Karina Mendes Veloso
Barbosa Júnior, Aryon de Almeida
Marcantonio Junior, Elcio
Goissis, Gilberto
Miguel, Fúlvio Borges
Rosa, Fabiana Paim
Cardoso, Ana Karina Mendes Veloso
Barbosa Júnior, Aryon de Almeida
Marcantonio Junior, Elcio
Goissis, Gilberto
dc.subject.por.fl_str_mv Tissue bioengineering;
Anionic collagen;
Three-dimensional matrix;
Bone regeneration
Critical size defect
topic Tissue bioengineering;
Anionic collagen;
Three-dimensional matrix;
Bone regeneration
Critical size defect
description Texto completo: acesso restrito. p.334–339
publishDate 2006
dc.date.issued.fl_str_mv 2006
dc.date.accessioned.fl_str_mv 2013-08-05T09:52:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/12435
dc.identifier.issn.none.fl_str_mv 1552-4973
dc.identifier.number.pt_BR.fl_str_mv v. 78 B n. 2
identifier_str_mv 1552-4973
v. 78 B n. 2
url http://www.repositorio.ufba.br/ri/handle/ri/12435
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/ 10.1002/jbm.b.30492
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