Prevalence of non-organ-specific autoantibodies in a rural community from northeastern Brazil: a population-based study

Detalhes bibliográficos
Autor(a) principal: Cunha, Liliane Monteiro
Data de Publicação: 2012
Outros Autores: Bittencourt, Paulo Lisboa, Lemos, Clarice P. Abrantes, Moreira, Agnaluce, Almeida, Delvone, Paraná, Raymundo, Andrade, Zilton de Araújo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/16181
Resumo: Texto completo: acesso restrito. p. 70–74
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spelling Cunha, Liliane MonteiroBittencourt, Paulo LisboaLemos, Clarice P. AbrantesMoreira, AgnaluceAlmeida, DelvoneParaná, RaymundoAndrade, Zilton de AraújoCunha, Liliane MonteiroBittencourt, Paulo LisboaLemos, Clarice P. AbrantesMoreira, AgnaluceAlmeida, DelvoneParaná, RaymundoAndrade, Zilton de Araújo2014-09-26T15:01:59Z20120198-8859http://repositorio.ufba.br/ri/handle/ri/16181v. 73, n. 1Texto completo: acesso restrito. p. 70–74Non-organ-specific autoantibodies (NOSA) are well-recognized diagnostic markers of autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC), but can also be observed in patients with viral hepatitis as well as in healthy subjects. The aim of this study was to evaluate the prevalence of NOSA in subjects living in a rural community in Brazil and to correlate their occurrence with the presence of liver disease. Seven hundred twenty-five apparently healthy subjects were randomly selected for assessment of antinuclear (ANA), anti-smooth muscle (SMA), antimitochondrial (AMA), anti-liver/kidney microsome type 1, and anti-liver cytosol type 1 antibodies. Subjects with those NOSA were evaluated for the presence of AIH, PBC, and viral hepatitis. Reactivities for all NOSA, SMA, ANA, and AMA were detected, respectively, in 14, 10, 4, and 0.1% of subjects, with a mean titer of 1:40. NOSA-positive subjects were significantly older and more frequently females. No correlation was observed between the occurrence of NOSA and PBC, AIH, or viral hepatitis. The prevalence of NOSA in Brazilians was 14%. They were usually low titer. NOSA were more frequently observed in females and older subjects and their presence was not correlated with the presence of AIH, PBC, or viral hepatitis.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-08-26T13:40:30Z No. of bitstreams: 1 Liliane M. Cunha.pdf: 292661 bytes, checksum: de73f388fe565caa2ab49f08661d281b (MD5)Rejected by Delba Rosa (delba@ufba.br), reason: Por gentileza, certifique-se do endereço eletrôico: http://dx.doi.org/ 10.1016/j.humimm.2011.10.00 on 2014-09-15T16:20:05Z (GMT)Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-09-17T11:58:01Z No. of bitstreams: 1 Liliane M. Cunha.pdf: 292661 bytes, checksum: de73f388fe565caa2ab49f08661d281b (MD5)Approved for entry into archive by Delba Rosa (delba@ufba.br) on 2014-09-26T15:01:59Z (GMT) No. of bitstreams: 1 Liliane M. Cunha.pdf: 292661 bytes, checksum: de73f388fe565caa2ab49f08661d281b (MD5)Made available in DSpace on 2014-09-26T15:01:59Z (GMT). No. of bitstreams: 1 Liliane M. Cunha.pdf: 292661 bytes, checksum: de73f388fe565caa2ab49f08661d281b (MD5) Previous issue date: 2012-01http://dx.doi.org/10.1016/j.humimm.2011.10.001reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAAutoantibodiesRural populationAutoimmunityAutoimmune diseasesLiver diseasesPrevalence of non-organ-specific autoantibodies in a rural community from northeastern Brazil: a population-based studyHuman Immunologyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALLiliane M. Cunha.pdfLiliane M. Cunha.pdfapplication/pdf292661https://repositorio.ufba.br/bitstream/ri/16181/1/Liliane%20M.%20Cunha.pdfde73f388fe565caa2ab49f08661d281bMD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/16181/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXTLiliane M. Cunha.pdf.txtLiliane M. 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dc.title.pt_BR.fl_str_mv Prevalence of non-organ-specific autoantibodies in a rural community from northeastern Brazil: a population-based study
dc.title.alternative.pt_BR.fl_str_mv Human Immunology
title Prevalence of non-organ-specific autoantibodies in a rural community from northeastern Brazil: a population-based study
spellingShingle Prevalence of non-organ-specific autoantibodies in a rural community from northeastern Brazil: a population-based study
Cunha, Liliane Monteiro
Autoantibodies
Rural population
Autoimmunity
Autoimmune diseases
Liver diseases
title_short Prevalence of non-organ-specific autoantibodies in a rural community from northeastern Brazil: a population-based study
title_full Prevalence of non-organ-specific autoantibodies in a rural community from northeastern Brazil: a population-based study
title_fullStr Prevalence of non-organ-specific autoantibodies in a rural community from northeastern Brazil: a population-based study
title_full_unstemmed Prevalence of non-organ-specific autoantibodies in a rural community from northeastern Brazil: a population-based study
title_sort Prevalence of non-organ-specific autoantibodies in a rural community from northeastern Brazil: a population-based study
author Cunha, Liliane Monteiro
author_facet Cunha, Liliane Monteiro
Bittencourt, Paulo Lisboa
Lemos, Clarice P. Abrantes
Moreira, Agnaluce
Almeida, Delvone
Paraná, Raymundo
Andrade, Zilton de Araújo
author_role author
author2 Bittencourt, Paulo Lisboa
Lemos, Clarice P. Abrantes
Moreira, Agnaluce
Almeida, Delvone
Paraná, Raymundo
Andrade, Zilton de Araújo
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Cunha, Liliane Monteiro
Bittencourt, Paulo Lisboa
Lemos, Clarice P. Abrantes
Moreira, Agnaluce
Almeida, Delvone
Paraná, Raymundo
Andrade, Zilton de Araújo
Cunha, Liliane Monteiro
Bittencourt, Paulo Lisboa
Lemos, Clarice P. Abrantes
Moreira, Agnaluce
Almeida, Delvone
Paraná, Raymundo
Andrade, Zilton de Araújo
dc.subject.por.fl_str_mv Autoantibodies
Rural population
Autoimmunity
Autoimmune diseases
Liver diseases
topic Autoantibodies
Rural population
Autoimmunity
Autoimmune diseases
Liver diseases
description Texto completo: acesso restrito. p. 70–74
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2014-09-26T15:01:59Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/16181
dc.identifier.issn.none.fl_str_mv 0198-8859
dc.identifier.number.pt_BR.fl_str_mv v. 73, n. 1
identifier_str_mv 0198-8859
v. 73, n. 1
url http://repositorio.ufba.br/ri/handle/ri/16181
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1016/j.humimm.2011.10.001
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
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