Association of matrix metalloproteinase gene polymorphism with temporomandibular joint degeneration
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/5549 |
Resumo: | Acesso restrito: Texto completo. p. 1-6 |
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Planello, Aline C.Campos, Maria Isabela GuimarãesMeloto, Carolina B.Secolin, RodrigoRizatti-Barbosa, Célia M.Line, Sergio R. P.Souza, Ana P. dePlanello, Aline C.Campos, Maria Isabela GuimarãesMeloto, Carolina B.Secolin, RodrigoRizatti-Barbosa, Célia M.Line, Sergio R. P.Souza, Ana P. de2012-03-21T19:12:46Z2011-020909-8836http://www.repositorio.ufba.br/ri/handle/ri/5549v. 119, n. 1Acesso restrito: Texto completo. p. 1-6Temporomandibular joint (TMJ) degeneration is a frequent cause of orofacial pain. Matrix metalloproteinases (MMPs) degrade extracellular matrix components and play an important role in TMJ degeneration. We investigated the frequency of the MMP1 1G/2G polymorphism (rs1799750), the MMP3 5A/6A polymorphism (rs3025058), and the MMP9 C/T polymorphism (rs3918242) in individuals with TMJ degeneration, in order to analyze the association of polymorphisms in these genes with TMJ degeneration. The population studied comprised 117 healthy controls and 115 individuals diagnosed with TMJ degeneration upon examination of magnetic resonance imaging (MRI) and computed tomography (CT) images. Genotypes were determined using PCR restriction fragment length polymorphism (RFLP). Logistic regression analyses revealed an association between the MMP1 2G/2G genotype and degeneration; in contrast, there was no association between either the MMP3 or the MMP9 genotype and degeneration. Our results may indicate a role for the MMP1 polymorphism in TMJ degeneration.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2012-03-21T19:12:46Z No. of bitstreams: 1 __onlinelibrary.wiley.co...614c947b69b27b9c2c63cb414765b.pdf: 135013 bytes, checksum: 6f7d48b53762a4279c823515356397c5 (MD5)Made available in DSpace on 2012-03-21T19:12:46Z (GMT). No. of bitstreams: 1 __onlinelibrary.wiley.co...614c947b69b27b9c2c63cb414765b.pdf: 135013 bytes, checksum: 6f7d48b53762a4279c823515356397c5 (MD5) Previous issue date: 2011-02DOI: 10.1111/j.1600-0722.2010.00803.xreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAGenetic polymorphismMatrix metalloproteinaseSingle nucleotide polymorphismTemporomandibular jointAssociation of matrix metalloproteinase gene polymorphism with temporomandibular joint degenerationEuropean Journal of Oral Sciencesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessORIGINAL__onlinelibrary.wiley.co...614c947b69b27b9c2c63cb414765b.pdf__onlinelibrary.wiley.co...614c947b69b27b9c2c63cb414765b.pdfapplication/pdf135013https://repositorio.ufba.br/bitstream/ri/5549/1/__onlinelibrary.wiley.co...614c947b69b27b9c2c63cb414765b.pdf6f7d48b53762a4279c823515356397c5MD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/5549/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT__onlinelibrary.wiley.co...614c947b69b27b9c2c63cb414765b.pdf.txt__onlinelibrary.wiley.co...614c947b69b27b9c2c63cb414765b.pdf.txtExtracted texttext/plain31442https://repositorio.ufba.br/bitstream/ri/5549/3/__onlinelibrary.wiley.co...614c947b69b27b9c2c63cb414765b.pdf.txt9ca6eb2ee984370929658a2703f4d81fMD53ri/55492022-07-05 14:03:43.279oai:repositorio.ufba.br:ri/5549VGVybW8gZGUgTGljZW7vv71hLCBu77+9byBleGNsdXNpdm8sIHBhcmEgbyBkZXDvv71zaXRvIG5vIHJlcG9zaXTvv71yaW8gSW5zdGl0dWNpb25hbCBkYSBVRkJBCgogICAgUGVsbyBwcm9jZXNzbyBkZSBzdWJtaXNz77+9byBkZSBkb2N1bWVudG9zLCBvIGF1dG9yIG91IHNldQpyZXByZXNlbnRhbnRlIGxlZ2FsLCBhbyBhY2VpdGFyIGVzc2UgdGVybW8gZGUgbGljZW7vv71hLCBjb25jZWRlIGFvClJlcG9zaXTvv71yaW8gSW5zdGl0dWNpb25hbCBkYSBVbml2ZXJzaWRhZGUgRmVkZXJhbCBkYSBCYWhpYSBvIGRpcmVpdG8KZGUgbWFudGVyIHVtYSBj77+9cGlhIGVtIHNldSByZXBvc2l077+9cmlvIGNvbSBhIGZpbmFsaWRhZGUsIHByaW1laXJhLCAKZGUgcHJlc2VydmHvv73vv71vLiBFc3NlcyB0ZXJtb3MsIG7vv71vIGV4Y2x1c2l2b3MsIG1hbnTvv71tIG9zIGRpcmVpdG9zIGRlIAphdXRvci9jb3B5cmlnaHQsIG1hcyBlbnRlbmRlIG8gZG9jdW1lbnRvIGNvbW8gcGFydGUgZG8gYWNlcnZvIGludGVsZWN0dWFsIGRlc3NhIFVuaXZlcnNpZGFkZS4gCgogICAgUGFyYSBvcyBkb2N1bWVudG9zIHB1YmxpY2Fkb3MgY29tIHJlcGFzc2UgZGUgZGlyZWl0b3MgZGUgZGlzdHJpYnVp77+977+9bywgZXNzZSB0ZXJtbyBkZSBsaWNlbu+/vWEgZW50ZW5kZSBxdWU6IAoKICAgIE1hbnRlbmRvIG9zICBkaXJlaXRvcyBhdXRvcmFpcywgcmVwYXNzYWRvcyBhIHRlcmNlaXJvcywgZW0gY2FzbyAKZGUgcHVibGljYe+/ve+/vWVzLCBvIHJlcG9zaXTvv71yaW8gcG9kZSByZXN0cmluZ2lyIG8gYWNlc3NvIGFvIHRleHRvIAppbnRlZ3JhbCwgbWFzIGxpYmVyYSBhcyBpbmZvcm1h77+977+9ZXMgc29icmUgbyBkb2N1bWVudG8gKE1ldGFkYWRvcyBkZXNjcml0aXZvcykuCgogRGVzdGEgZm9ybWEsIGF0ZW5kZW5kbyBhb3MgYW5zZWlvcyBkZXNzYSB1bml2ZXJzaWRhZGUgCmVtIG1hbnRlciBzdWEgcHJvZHXvv73vv71vIGNpZW5077+9ZmljYSBjb20gYXMgcmVzdHJp77+977+9ZXMgaW1wb3N0YXMgcGVsb3MgCmVkaXRvcmVzIGRlIHBlcmnvv71kaWNvcy4gCgogICAgUGFyYSBhcyBwdWJsaWNh77+977+9ZXMgZW0gaW5pY2lhdGl2YXMgcXVlIHNlZ3VlbSBhIHBvbO+/vXRpY2EgZGUgCkFjZXNzbyBBYmVydG8sIG9zIGRlcO+/vXNpdG9zIGNvbXB1bHPvv71yaW9zIG5lc3NlIHJlcG9zaXTvv71yaW8gbWFudO+/vW0gCm9zIGRpcmVpdG9zIGF1dG9yYWlzLCBtYXMgbWFudO+/vW0gbyBhY2Vzc28gaXJyZXN0cml0byBhbyBtZXRhZGFkb3MgCmUgdGV4dG8gY29tcGxldG8uIEFzc2ltLCBhIGFjZWl0Ye+/ve+/vW8gZGVzc2UgdGVybW8gbu+/vW8gbmVjZXNzaXRhIGRlIApjb25zZW50aW1lbnRvIHBvciBwYXJ0ZSBkZSBhdXRvcmVzL2RldGVudG9yZXMgZG9zIGRpcmVpdG9zLCBwb3IgCmVzdGFyZW0gZW0gaW5pY2lhdGl2YXMgZGUgYWNlc3NvIGFiZXJ0by4KCiAgICBFbSBhbWJvcyBvIGNhc28sIGVzc2UgdGVybW8gZGUgbGljZW7vv71hLCBwb2RlIHNlciBhY2VpdG8gcGVsbyAKYXV0b3IsIGRldGVudG9yZXMgZGUgZGlyZWl0b3MgZS9vdSB0ZXJjZWlyb3MgYW1wYXJhZG9zIHBlbGEgCnVuaXZlcnNpZGFkZS4gRGV2aWRvIGFvcyBkaWZlcmVudGVzIHByb2Nlc3NvcyBwZWxvIHF1YWwgYSBzdWJtaXNz77+9byAKcG9kZSBvY29ycmVyLCBvIHJlcG9zaXTvv71yaW8gcGVybWl0ZSBhIGFjZWl0Ye+/ve+/vW8gZGEgbGljZW7vv71hIHBvciAKdGVyY2Vpcm9zLCBzb21lbnRlIG5vcyBjYXNvcyBkZSBkb2N1bWVudG9zIHByb2R1emlkb3MgcG9yIGludGVncmFudGVzIApkYSBVRkJBIGUgc3VibWV0aWRvcyBwb3IgcGVzc29hcyBhbXBhcmFkYXMgcG9yIGVzdGEgaW5zdGl0dWnvv73vv71vLgo=Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:43Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
Association of matrix metalloproteinase gene polymorphism with temporomandibular joint degeneration |
dc.title.alternative.pt_BR.fl_str_mv |
European Journal of Oral Sciences |
title |
Association of matrix metalloproteinase gene polymorphism with temporomandibular joint degeneration |
spellingShingle |
Association of matrix metalloproteinase gene polymorphism with temporomandibular joint degeneration Planello, Aline C. Genetic polymorphism Matrix metalloproteinase Single nucleotide polymorphism Temporomandibular joint |
title_short |
Association of matrix metalloproteinase gene polymorphism with temporomandibular joint degeneration |
title_full |
Association of matrix metalloproteinase gene polymorphism with temporomandibular joint degeneration |
title_fullStr |
Association of matrix metalloproteinase gene polymorphism with temporomandibular joint degeneration |
title_full_unstemmed |
Association of matrix metalloproteinase gene polymorphism with temporomandibular joint degeneration |
title_sort |
Association of matrix metalloproteinase gene polymorphism with temporomandibular joint degeneration |
author |
Planello, Aline C. |
author_facet |
Planello, Aline C. Campos, Maria Isabela Guimarães Meloto, Carolina B. Secolin, Rodrigo Rizatti-Barbosa, Célia M. Line, Sergio R. P. Souza, Ana P. de |
author_role |
author |
author2 |
Campos, Maria Isabela Guimarães Meloto, Carolina B. Secolin, Rodrigo Rizatti-Barbosa, Célia M. Line, Sergio R. P. Souza, Ana P. de |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Planello, Aline C. Campos, Maria Isabela Guimarães Meloto, Carolina B. Secolin, Rodrigo Rizatti-Barbosa, Célia M. Line, Sergio R. P. Souza, Ana P. de Planello, Aline C. Campos, Maria Isabela Guimarães Meloto, Carolina B. Secolin, Rodrigo Rizatti-Barbosa, Célia M. Line, Sergio R. P. Souza, Ana P. de |
dc.subject.por.fl_str_mv |
Genetic polymorphism Matrix metalloproteinase Single nucleotide polymorphism Temporomandibular joint |
topic |
Genetic polymorphism Matrix metalloproteinase Single nucleotide polymorphism Temporomandibular joint |
description |
Acesso restrito: Texto completo. p. 1-6 |
publishDate |
2011 |
dc.date.issued.fl_str_mv |
2011-02 |
dc.date.accessioned.fl_str_mv |
2012-03-21T19:12:46Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.repositorio.ufba.br/ri/handle/ri/5549 |
dc.identifier.issn.none.fl_str_mv |
0909-8836 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 119, n. 1 |
identifier_str_mv |
0909-8836 v. 119, n. 1 |
url |
http://www.repositorio.ufba.br/ri/handle/ri/5549 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.pt_BR.fl_str_mv |
DOI: 10.1111/j.1600-0722.2010.00803.x |
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UFBA |
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