Correlation between 25-hydroxyvitamin D levels and latitude in Brazilian postmenopausal women: from the Arzoxifene Generations Trial

Detalhes bibliográficos
Autor(a) principal: Arantes, H. P.
Data de Publicação: 2013
Outros Autores: Kulak, C. A. M., Fernandes, C. E., Zerbini, C., Bandeira, F., Barbosa, Ione Cristina, Brenol, J. C. T., Russo, L. A., Borba, V. C., Chiang, A. Y., Bilezikian, J. P., Castro, M. Lazaretti
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/16375
Resumo: Texto completo: acesso restrito. p. 2707-2712
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spelling Arantes, H. P.Kulak, C. A. M.Fernandes, C. E.Zerbini, C.Bandeira, F.Barbosa, Ione CristinaBrenol, J. C. T.Russo, L. A.Borba, V. C.Chiang, A. Y.Bilezikian, J. P.Castro, M. LazarettiArantes, H. P.Kulak, C. A. M.Fernandes, C. E.Zerbini, C.Bandeira, F.Barbosa, Ione CristinaBrenol, J. C. T.Russo, L. A.Borba, V. C.Chiang, A. Y.Bilezikian, J. P.Castro, M. Lazaretti2014-10-10T15:06:12Z20130937-941Xhttp://repositorio.ufba.br/ri/handle/ri/16375v. 24, n. 10Texto completo: acesso restrito. p. 2707-2712Summary: We investigated vitamin D status in Brazilian cities located at different latitudes. Insufficiency (<50 nmol/L) was common (17 %), even in those living in a tropical climate. Vitamin D insufficiency increased as a function of latitude. Mean 25-hydroxyvitamin D (25(OH)D) levels in each site and latitude correlation were very high (r = −0.88; p < 0.0001). Introduction: Inadequate vitamin D, determined by low levels of 25(OH)D, has become very common despite the availability of sunlight at some latitudes. National data from a country that spans a wide range of latitudes would help to determine to what extent latitude or other factors are responsible for vitamin D deficiency. We investigated vitamin D status in cities located at different latitudes in Brazil, a large continental country. Methods: The source is the Brazilian database from the Generations Trial (1,933 osteopenic or osteoporotic postmenopausal women (60 to 85 years old) with 25(OH)D measurements). 25(OH)D below 25 nmol/L (10 ng/mL) was an exclusion criterion. Baseline values were between fall and winter. The sites included Recife, Salvador, Rio de Janeiro, São Paulo, Curitiba, and Porto Alegre. Mean and standard deviation of 25(OH)D, age, spine and femoral neck T-score, calcium, creatinine, and alkaline phosphatase were calculated for each city. Pearson correlation was used for 25(OH)D and latitude. Results: Insufficiency (<50 or <20 ng/mL) was common (329 subjects, 17 %). Vitamin D insufficiency increased as a function of latitude, reaching 24.5 % in the southernmost city, Porto Alegre. The correlation between mean 25(OH)D levels in each site and latitude was very high (r = −0.88, p < 0.0001). Conclusion: There is a high percentage of individuals with vitamin D insufficiency in Brazil, even in cities near the equator, and this percentage progressively increases with more southern latitudes.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-04-24T14:44:50Z No. of bitstreams: 1 art%3A10.1007%2Fs00198-013-2366-x.pdf: 237162 bytes, checksum: 2bf79457234fed461a275f4597555f8f (MD5)Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2014-10-10T15:06:12Z (GMT) No. of bitstreams: 1 art%3A10.1007%2Fs00198-013-2366-x.pdf: 237162 bytes, checksum: 2bf79457234fed461a275f4597555f8f (MD5)Made available in DSpace on 2014-10-10T15:06:12Z (GMT). No. of bitstreams: 1 art%3A10.1007%2Fs00198-013-2366-x.pdf: 237162 bytes, checksum: 2bf79457234fed461a275f4597555f8f (MD5) Previous issue date: 2013http://dx.doi.org/10.1007/s00198-013-2366-xreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBABrazilian postmenopausalLatitudeVitamin D insufficiencyZenith angleCorrelation between 25-hydroxyvitamin D levels and latitude in Brazilian postmenopausal women: from the Arzoxifene Generations TrialOsteoporosis Internationalinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALart%3A10.1007%2Fs00198-013-2366-x.pdfart%3A10.1007%2Fs00198-013-2366-x.pdfapplication/pdf237162https://repositorio.ufba.br/bitstream/ri/16375/1/art%253A10.1007%252Fs00198-013-2366-x.pdf2bf79457234fed461a275f4597555f8fMD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/16375/2/license.txt0d4b811ef71182510d2015daa7c8a900MD52TEXTart%3A10.1007%2Fs00198-013-2366-x.pdf.txtart%3A10.1007%2Fs00198-013-2366-x.pdf.txtExtracted texttext/plain24569https://repositorio.ufba.br/bitstream/ri/16375/3/art%253A10.1007%252Fs00198-013-2366-x.pdf.txt60bc70e93c66997cac2ce1160cf57288MD53ri/163752022-08-08 13:17:31.343oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-08-08T16:17:31Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Correlation between 25-hydroxyvitamin D levels and latitude in Brazilian postmenopausal women: from the Arzoxifene Generations Trial
dc.title.alternative.pt_BR.fl_str_mv Osteoporosis International
title Correlation between 25-hydroxyvitamin D levels and latitude in Brazilian postmenopausal women: from the Arzoxifene Generations Trial
spellingShingle Correlation between 25-hydroxyvitamin D levels and latitude in Brazilian postmenopausal women: from the Arzoxifene Generations Trial
Arantes, H. P.
Brazilian postmenopausal
Latitude
Vitamin D insufficiency
Zenith angle
title_short Correlation between 25-hydroxyvitamin D levels and latitude in Brazilian postmenopausal women: from the Arzoxifene Generations Trial
title_full Correlation between 25-hydroxyvitamin D levels and latitude in Brazilian postmenopausal women: from the Arzoxifene Generations Trial
title_fullStr Correlation between 25-hydroxyvitamin D levels and latitude in Brazilian postmenopausal women: from the Arzoxifene Generations Trial
title_full_unstemmed Correlation between 25-hydroxyvitamin D levels and latitude in Brazilian postmenopausal women: from the Arzoxifene Generations Trial
title_sort Correlation between 25-hydroxyvitamin D levels and latitude in Brazilian postmenopausal women: from the Arzoxifene Generations Trial
author Arantes, H. P.
author_facet Arantes, H. P.
Kulak, C. A. M.
Fernandes, C. E.
Zerbini, C.
Bandeira, F.
Barbosa, Ione Cristina
Brenol, J. C. T.
Russo, L. A.
Borba, V. C.
Chiang, A. Y.
Bilezikian, J. P.
Castro, M. Lazaretti
author_role author
author2 Kulak, C. A. M.
Fernandes, C. E.
Zerbini, C.
Bandeira, F.
Barbosa, Ione Cristina
Brenol, J. C. T.
Russo, L. A.
Borba, V. C.
Chiang, A. Y.
Bilezikian, J. P.
Castro, M. Lazaretti
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Arantes, H. P.
Kulak, C. A. M.
Fernandes, C. E.
Zerbini, C.
Bandeira, F.
Barbosa, Ione Cristina
Brenol, J. C. T.
Russo, L. A.
Borba, V. C.
Chiang, A. Y.
Bilezikian, J. P.
Castro, M. Lazaretti
Arantes, H. P.
Kulak, C. A. M.
Fernandes, C. E.
Zerbini, C.
Bandeira, F.
Barbosa, Ione Cristina
Brenol, J. C. T.
Russo, L. A.
Borba, V. C.
Chiang, A. Y.
Bilezikian, J. P.
Castro, M. Lazaretti
dc.subject.por.fl_str_mv Brazilian postmenopausal
Latitude
Vitamin D insufficiency
Zenith angle
topic Brazilian postmenopausal
Latitude
Vitamin D insufficiency
Zenith angle
description Texto completo: acesso restrito. p. 2707-2712
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2014-10-10T15:06:12Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.issn.none.fl_str_mv 0937-941X
dc.identifier.number.pt_BR.fl_str_mv v. 24, n. 10
identifier_str_mv 0937-941X
v. 24, n. 10
url http://repositorio.ufba.br/ri/handle/ri/16375
dc.language.iso.fl_str_mv eng
language eng
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