Insulin-like growth factor-I induced and constitutive arginase activity differs among isolates of Leishmania derived from patients with diverse clinical forms of Leishmania braziliensis infection

Detalhes bibliográficos
Autor(a) principal: Vendrame, Célia M. V.
Data de Publicação: 2010
Outros Autores: Souza, Luana D., Carvalho, Márcia D. T., Salgado, Kátia, Carvalho Filho, Edgar Marcelino de, Goto, Hiro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/5683
Resumo: Acesso restrito: Texto completo. p. 566-568.
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spelling Vendrame, Célia M. V.Souza, Luana D.Carvalho, Márcia D. T.Salgado, KátiaCarvalho Filho, Edgar Marcelino deGoto, HiroVendrame, Célia M. V.Souza, Luana D.Carvalho, Márcia D. T.Salgado, KátiaCarvalho Filho, Edgar Marcelino deGoto, Hiro2012-04-20T12:41:51Z20100035-9203http://www.repositorio.ufba.br/ri/handle/ri/5683v. 104, v. 8Acesso restrito: Texto completo. p. 566-568.Arginase activity has been related to leishmaniasis development, thus we studied the constitutive and insulin-like growth factor (IGF) I-induced arginase activity of Leishmania (Viannia) braziliensis isolates from patients with different clinical forms of American tegumentary leishmaniasis (ATL). Isolates from mucosal leishmaniasis presented higher basal levels of arginase activity than isolates from other clinical forms of ATL. Isolates from disseminated leishmaniasis that present mucosal lesion in some cases reached the arginase activity similar to that of isolates from mucosal leishmaniasis upon IGF-I stimulation. Differences in arginase activity may influence disease outcomes such as evolution to mucosal lesion in patients with L. (V.) braziliensis infection.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2012-04-20T12:41:51Z No. of bitstreams: 1 __ac.els-cdn.com_S003592...5da97e17f0cfad0829dec221b8ae9.pdf: 105057 bytes, checksum: 5d1a0868d78012b6c2bb88fc2bc14e99 (MD5)Made available in DSpace on 2012-04-20T12:41:51Z (GMT). No. of bitstreams: 1 __ac.els-cdn.com_S003592...5da97e17f0cfad0829dec221b8ae9.pdf: 105057 bytes, checksum: 5d1a0868d78012b6c2bb88fc2bc14e99 (MD5) Previous issue date: 2010-08DOI: 10.1016/j.trstmh.2010.03.007reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBALeishmania braziliensisCutaneous leishmaniasisMucosal leishmaniasisDisseminated leishmaniasisArginaseInsulin-like growth factor IInsulin-like growth factor-I induced and constitutive arginase activity differs among isolates of Leishmania derived from patients with diverse clinical forms of Leishmania braziliensis infectionTransactions of the royal society of tropical medicine and hygieneinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessORIGINAL__ac.els-cdn.com_S003592...5da97e17f0cfad0829dec221b8ae9.pdf__ac.els-cdn.com_S003592...5da97e17f0cfad0829dec221b8ae9.pdfapplication/pdf105057https://repositorio.ufba.br/bitstream/ri/5683/1/__ac.els-cdn.com_S003592...5da97e17f0cfad0829dec221b8ae9.pdf5d1a0868d78012b6c2bb88fc2bc14e99MD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/5683/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT__ac.els-cdn.com_S003592...5da97e17f0cfad0829dec221b8ae9.pdf.txt__ac.els-cdn.com_S003592...5da97e17f0cfad0829dec221b8ae9.pdf.txtExtracted texttext/plain10921https://repositorio.ufba.br/bitstream/ri/5683/3/__ac.els-cdn.com_S003592...5da97e17f0cfad0829dec221b8ae9.pdf.txtda6057bf80842c02b7827c3fba5986caMD53ri/56832022-10-31 20:13:31.374oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-10-31T23:13:31Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Insulin-like growth factor-I induced and constitutive arginase activity differs among isolates of Leishmania derived from patients with diverse clinical forms of Leishmania braziliensis infection
dc.title.alternative.pt_BR.fl_str_mv Transactions of the royal society of tropical medicine and hygiene
title Insulin-like growth factor-I induced and constitutive arginase activity differs among isolates of Leishmania derived from patients with diverse clinical forms of Leishmania braziliensis infection
spellingShingle Insulin-like growth factor-I induced and constitutive arginase activity differs among isolates of Leishmania derived from patients with diverse clinical forms of Leishmania braziliensis infection
Vendrame, Célia M. V.
Leishmania braziliensis
Cutaneous leishmaniasis
Mucosal leishmaniasis
Disseminated leishmaniasis
Arginase
Insulin-like growth factor I
title_short Insulin-like growth factor-I induced and constitutive arginase activity differs among isolates of Leishmania derived from patients with diverse clinical forms of Leishmania braziliensis infection
title_full Insulin-like growth factor-I induced and constitutive arginase activity differs among isolates of Leishmania derived from patients with diverse clinical forms of Leishmania braziliensis infection
title_fullStr Insulin-like growth factor-I induced and constitutive arginase activity differs among isolates of Leishmania derived from patients with diverse clinical forms of Leishmania braziliensis infection
title_full_unstemmed Insulin-like growth factor-I induced and constitutive arginase activity differs among isolates of Leishmania derived from patients with diverse clinical forms of Leishmania braziliensis infection
title_sort Insulin-like growth factor-I induced and constitutive arginase activity differs among isolates of Leishmania derived from patients with diverse clinical forms of Leishmania braziliensis infection
author Vendrame, Célia M. V.
author_facet Vendrame, Célia M. V.
Souza, Luana D.
Carvalho, Márcia D. T.
Salgado, Kátia
Carvalho Filho, Edgar Marcelino de
Goto, Hiro
author_role author
author2 Souza, Luana D.
Carvalho, Márcia D. T.
Salgado, Kátia
Carvalho Filho, Edgar Marcelino de
Goto, Hiro
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Vendrame, Célia M. V.
Souza, Luana D.
Carvalho, Márcia D. T.
Salgado, Kátia
Carvalho Filho, Edgar Marcelino de
Goto, Hiro
Vendrame, Célia M. V.
Souza, Luana D.
Carvalho, Márcia D. T.
Salgado, Kátia
Carvalho Filho, Edgar Marcelino de
Goto, Hiro
dc.subject.por.fl_str_mv Leishmania braziliensis
Cutaneous leishmaniasis
Mucosal leishmaniasis
Disseminated leishmaniasis
Arginase
Insulin-like growth factor I
topic Leishmania braziliensis
Cutaneous leishmaniasis
Mucosal leishmaniasis
Disseminated leishmaniasis
Arginase
Insulin-like growth factor I
description Acesso restrito: Texto completo. p. 566-568.
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2012-04-20T12:41:51Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/5683
dc.identifier.issn.none.fl_str_mv 0035-9203
dc.identifier.number.pt_BR.fl_str_mv v. 104, v. 8
identifier_str_mv 0035-9203
v. 104, v. 8
url http://www.repositorio.ufba.br/ri/handle/ri/5683
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv DOI: 10.1016/j.trstmh.2010.03.007
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
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