Effect of laser and LED phototherapies on the healing of cutaneous wound on healthy and iron-deficient Wistar rats and their impact on fibroblastic activity during wound healing
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2013 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFBA |
| Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/12125 |
Resumo: | Texto completo. Acesso restrito. p. 799-806 |
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Sampaio, Susana C. P. OliveiraMonteiro, Juliana S. de C.Cangussu, Maria Cristina TeixeiraSantos, Gustavo M. PiresSantos, Marcos André Vannier dosSantos, Jean Nunes dosPinheiro, Antonio Luiz BarbosaSampaio, Susana C. P. OliveiraMonteiro, Juliana S. de C.Cangussu, Maria Cristina TeixeiraSantos, Gustavo M. PiresSantos, Marcos André Vannier dosSantos, Jean Nunes dosPinheiro, Antonio Luiz Barbosa2013-07-08T15:20:29Z2013-07-08T15:20:29Z20130268-8921http://www.repositorio.ufba.br/ri/handle/ri/12125v. 28, n. 3Texto completo. Acesso restrito. p. 799-806Iron deficiency impairs the formation of hemoglobin, red blood cells, as well the transport of oxygen. The wound healing process involves numerous functions, many of which are dependent on the presence of oxygen. Laser has been shown to improve angiogenesis, increases blood supply, cell proliferation and function.We aimed to study the effect of λ660 nm laser and λ700 nm light-emitting diode (LED) on fibroblastic proliferation on cutaneous wounds on irondeficient rodents. Induction of iron anemia was carried out by feeding 105 newborn rats with a special iron-free diet. A 1×1 cmwound was created on the dorsumof each animal that were randomly distributed into seven groups: I, control anemic; II, anemic no treatment; III, anemic+L; IV, anemic+ LED; V, healthy no treatment; VI, healthy+laser; VII, healthy+ LED (n015 each). Phototherapy was carried out using either a diode laser (λ660 nm, 40 mW, 10 J/cm2) or a prototype LED device (λ700±20 nm, 15 mW, 10 J/cm2). Treatment started immediately after surgery and was repeated at 48-h interval during 7, 14, and 21 days. After animal death, specimens were taken, routinely processed, cut, stainedwith hematoxylin-eosin, and underwent histological analysis and fibroblast counting. Significant difference between healthy and anemic subjects on regards the number of fibroblast between treatments was seen (p<0.008, p<0.001). On healthy animals, significant higher count was seen when laser was used (p<0.008). Anemic subjects irradiated with LED showed significantly higher count (p<0.001). It is concluded that the use of LED light caused a significant positive biomodulation of fibroblastic proliferation on anemic animals and laser was more effective on increasing proliferation on non-anemics.Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2013-06-12T19:28:04Z No. of bitstreams: 1 999999999999999.pdf: 596479 bytes, checksum: 3f816d2fe808e6e420b7fe1e50f1b436 (MD5)Approved for entry into archive by Flávia Ferreira(flaviaccf@yahoo.com.br) on 2013-07-08T15:20:29Z (GMT) No. of bitstreams: 1 999999999999999.pdf: 596479 bytes, checksum: 3f816d2fe808e6e420b7fe1e50f1b436 (MD5)Made available in DSpace on 2013-07-08T15:20:29Z (GMT). No. of bitstreams: 1 999999999999999.pdf: 596479 bytes, checksum: 3f816d2fe808e6e420b7fe1e50f1b436 (MD5) Previous issue date: 2013SalvadorLasers in Medical Science10.1007/s10103-012-1161-9reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAAnemiaPhototherapyWound healingEffect of laser and LED phototherapies on the healing of cutaneous wound on healthy and iron-deficient Wistar rats and their impact on fibroblastic activity during wound healingLasers in Medical Scienceinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleenginfo:eu-repo/semantics/openAccessORIGINAL999999999999999.pdf999999999999999.pdfapplication/pdf596479https://repositorio.ufba.br/bitstream/ri/12125/1/999999999999999.pdf3f816d2fe808e6e420b7fe1e50f1b436MD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/12125/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT999999999999999.pdf.txt999999999999999.pdf.txtExtracted texttext/plain34952https://repositorio.ufba.br/bitstream/ri/12125/3/999999999999999.pdf.txtd13b96b83a82060abdb5e87876999e1dMD53ri/121252022-07-05 14:03:22.034oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:22Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
| dc.title.pt_BR.fl_str_mv |
Effect of laser and LED phototherapies on the healing of cutaneous wound on healthy and iron-deficient Wistar rats and their impact on fibroblastic activity during wound healing |
| dc.title.alternative.pt_BR.fl_str_mv |
Lasers in Medical Science |
| title |
Effect of laser and LED phototherapies on the healing of cutaneous wound on healthy and iron-deficient Wistar rats and their impact on fibroblastic activity during wound healing |
| spellingShingle |
Effect of laser and LED phototherapies on the healing of cutaneous wound on healthy and iron-deficient Wistar rats and their impact on fibroblastic activity during wound healing Sampaio, Susana C. P. Oliveira Anemia Phototherapy Wound healing |
| title_short |
Effect of laser and LED phototherapies on the healing of cutaneous wound on healthy and iron-deficient Wistar rats and their impact on fibroblastic activity during wound healing |
| title_full |
Effect of laser and LED phototherapies on the healing of cutaneous wound on healthy and iron-deficient Wistar rats and their impact on fibroblastic activity during wound healing |
| title_fullStr |
Effect of laser and LED phototherapies on the healing of cutaneous wound on healthy and iron-deficient Wistar rats and their impact on fibroblastic activity during wound healing |
| title_full_unstemmed |
Effect of laser and LED phototherapies on the healing of cutaneous wound on healthy and iron-deficient Wistar rats and their impact on fibroblastic activity during wound healing |
| title_sort |
Effect of laser and LED phototherapies on the healing of cutaneous wound on healthy and iron-deficient Wistar rats and their impact on fibroblastic activity during wound healing |
| author |
Sampaio, Susana C. P. Oliveira |
| author_facet |
Sampaio, Susana C. P. Oliveira Monteiro, Juliana S. de C. Cangussu, Maria Cristina Teixeira Santos, Gustavo M. Pires Santos, Marcos André Vannier dos Santos, Jean Nunes dos Pinheiro, Antonio Luiz Barbosa |
| author_role |
author |
| author2 |
Monteiro, Juliana S. de C. Cangussu, Maria Cristina Teixeira Santos, Gustavo M. Pires Santos, Marcos André Vannier dos Santos, Jean Nunes dos Pinheiro, Antonio Luiz Barbosa |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Sampaio, Susana C. P. Oliveira Monteiro, Juliana S. de C. Cangussu, Maria Cristina Teixeira Santos, Gustavo M. Pires Santos, Marcos André Vannier dos Santos, Jean Nunes dos Pinheiro, Antonio Luiz Barbosa Sampaio, Susana C. P. Oliveira Monteiro, Juliana S. de C. Cangussu, Maria Cristina Teixeira Santos, Gustavo M. Pires Santos, Marcos André Vannier dos Santos, Jean Nunes dos Pinheiro, Antonio Luiz Barbosa |
| dc.subject.por.fl_str_mv |
Anemia Phototherapy Wound healing |
| topic |
Anemia Phototherapy Wound healing |
| description |
Texto completo. Acesso restrito. p. 799-806 |
| publishDate |
2013 |
| dc.date.accessioned.fl_str_mv |
2013-07-08T15:20:29Z |
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2013-07-08T15:20:29Z |
| dc.date.issued.fl_str_mv |
2013 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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http://www.repositorio.ufba.br/ri/handle/ri/12125 |
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0268-8921 |
| dc.identifier.number.pt_BR.fl_str_mv |
v. 28, n. 3 |
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0268-8921 v. 28, n. 3 |
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http://www.repositorio.ufba.br/ri/handle/ri/12125 |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
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Lasers in Medical Science |
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Lasers in Medical Science |
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10.1007/s10103-012-1161-9 |
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reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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