Leishmania mexicana: Immunology and histopathology in C3H mice

Detalhes bibliográficos
Autor(a) principal: Grimaldi Jr., Gabriel
Data de Publicação: 1980
Outros Autores: Moriearty, Pamela Lane
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/8717
Resumo: Texto completo. Acesso restrito. p. 45 – 56
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spelling Grimaldi Jr., GabrielMoriearty, Pamela LaneGrimaldi Jr., GabrielMoriearty, Pamela Lane2013-02-28T16:42:29Z2013-02-28T16:42:29Z19800014-4894http://www.repositorio.ufba.br/ri/handle/ri/8717v. 50, n. 1Texto completo. Acesso restrito. p. 45 – 56Leishmania mexicana: Immunology and histopathology in C3H mice. Experimental Parasitology 50, 45-56. C3H mice were infected subcutaneously with lo5 promastigotes of Leishmania mexicana and subsequent lesions were examined at 3, 5, and 8 months. All animals developed persistent nonulcerating nodules of variable size which did not metastasize. The nodules contained amastigotes with a mononuclear infiltrate of histiocytes, lymphocytes, and plasma cells, but without formation of tuberculoid-type granulomas. Neutrophils and eosinophils were also encountered in some cases. Specific antileishmanial antibodies and delayed-type hypersensitivity to leishmanial antigen were present at 3, 5, and 8 months postinfection. L. mexicana infection in C3H mice differs from classic self-healing cutaneous leishmaniasis by the persistence of nonhealing, nonulcerating, nonmetastasizing lesions, despite evidence of cellular and humoral immunity.Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2013-02-21T21:13:07Z No. of bitstreams: 1 qqqqqqq7575.pdf: 2254180 bytes, checksum: d3ca5032406a27a136f2a82e35aac6f7 (MD5)Approved for entry into archive by Fatima Cleômenis Botelho Maria (botelho@ufba.br) on 2013-02-28T16:42:29Z (GMT) No. of bitstreams: 1 qqqqqqq7575.pdf: 2254180 bytes, checksum: d3ca5032406a27a136f2a82e35aac6f7 (MD5)Made available in DSpace on 2013-02-28T16:42:29Z (GMT). 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dc.title.pt_BR.fl_str_mv Leishmania mexicana: Immunology and histopathology in C3H mice
dc.title.alternative.pt_BR.fl_str_mv Experimental Parasitology
title Leishmania mexicana: Immunology and histopathology in C3H mice
spellingShingle Leishmania mexicana: Immunology and histopathology in C3H mice
Grimaldi Jr., Gabriel
Leishmania mexicana
Protozoa
parasitic
Hemoflagellate
Mice
C3H
Leishmaniasis
cutaneous
Immunofluorescence
Indirect hemagglutination
Delayed hypersensitivity
Ear thickness test
Histopathology
title_short Leishmania mexicana: Immunology and histopathology in C3H mice
title_full Leishmania mexicana: Immunology and histopathology in C3H mice
title_fullStr Leishmania mexicana: Immunology and histopathology in C3H mice
title_full_unstemmed Leishmania mexicana: Immunology and histopathology in C3H mice
title_sort Leishmania mexicana: Immunology and histopathology in C3H mice
author Grimaldi Jr., Gabriel
author_facet Grimaldi Jr., Gabriel
Moriearty, Pamela Lane
author_role author
author2 Moriearty, Pamela Lane
author2_role author
dc.contributor.author.fl_str_mv Grimaldi Jr., Gabriel
Moriearty, Pamela Lane
Grimaldi Jr., Gabriel
Moriearty, Pamela Lane
dc.subject.por.fl_str_mv Leishmania mexicana
Protozoa
parasitic
Hemoflagellate
Mice
C3H
Leishmaniasis
cutaneous
Immunofluorescence
Indirect hemagglutination
Delayed hypersensitivity
Ear thickness test
Histopathology
topic Leishmania mexicana
Protozoa
parasitic
Hemoflagellate
Mice
C3H
Leishmaniasis
cutaneous
Immunofluorescence
Indirect hemagglutination
Delayed hypersensitivity
Ear thickness test
Histopathology
description Texto completo. Acesso restrito. p. 45 – 56
publishDate 1980
dc.date.issued.fl_str_mv 1980
dc.date.accessioned.fl_str_mv 2013-02-28T16:42:29Z
dc.date.available.fl_str_mv 2013-02-28T16:42:29Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
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dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/8717
dc.identifier.issn.none.fl_str_mv 0014-4894
dc.identifier.number.pt_BR.fl_str_mv v. 50, n. 1
identifier_str_mv 0014-4894
v. 50, n. 1
url http://www.repositorio.ufba.br/ri/handle/ri/8717
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Experimental Parasitology
publisher.none.fl_str_mv Experimental Parasitology
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1016/0014-4894(80)90006-5
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
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instname_str Universidade Federal da Bahia (UFBA)
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reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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