Leishmania mexicana: Immunology and histopathology in C3H mice
Autor(a) principal: | |
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Data de Publicação: | 1980 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/8717 |
Resumo: | Texto completo. Acesso restrito. p. 45 – 56 |
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Grimaldi Jr., GabrielMoriearty, Pamela LaneGrimaldi Jr., GabrielMoriearty, Pamela Lane2013-02-28T16:42:29Z2013-02-28T16:42:29Z19800014-4894http://www.repositorio.ufba.br/ri/handle/ri/8717v. 50, n. 1Texto completo. Acesso restrito. p. 45 – 56Leishmania mexicana: Immunology and histopathology in C3H mice. Experimental Parasitology 50, 45-56. C3H mice were infected subcutaneously with lo5 promastigotes of Leishmania mexicana and subsequent lesions were examined at 3, 5, and 8 months. All animals developed persistent nonulcerating nodules of variable size which did not metastasize. The nodules contained amastigotes with a mononuclear infiltrate of histiocytes, lymphocytes, and plasma cells, but without formation of tuberculoid-type granulomas. Neutrophils and eosinophils were also encountered in some cases. Specific antileishmanial antibodies and delayed-type hypersensitivity to leishmanial antigen were present at 3, 5, and 8 months postinfection. L. mexicana infection in C3H mice differs from classic self-healing cutaneous leishmaniasis by the persistence of nonhealing, nonulcerating, nonmetastasizing lesions, despite evidence of cellular and humoral immunity.Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2013-02-21T21:13:07Z No. of bitstreams: 1 qqqqqqq7575.pdf: 2254180 bytes, checksum: d3ca5032406a27a136f2a82e35aac6f7 (MD5)Approved for entry into archive by Fatima Cleômenis Botelho Maria (botelho@ufba.br) on 2013-02-28T16:42:29Z (GMT) No. of bitstreams: 1 qqqqqqq7575.pdf: 2254180 bytes, checksum: d3ca5032406a27a136f2a82e35aac6f7 (MD5)Made available in DSpace on 2013-02-28T16:42:29Z (GMT). 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dc.title.pt_BR.fl_str_mv |
Leishmania mexicana: Immunology and histopathology in C3H mice |
dc.title.alternative.pt_BR.fl_str_mv |
Experimental Parasitology |
title |
Leishmania mexicana: Immunology and histopathology in C3H mice |
spellingShingle |
Leishmania mexicana: Immunology and histopathology in C3H mice Grimaldi Jr., Gabriel Leishmania mexicana Protozoa parasitic Hemoflagellate Mice C3H Leishmaniasis cutaneous Immunofluorescence Indirect hemagglutination Delayed hypersensitivity Ear thickness test Histopathology |
title_short |
Leishmania mexicana: Immunology and histopathology in C3H mice |
title_full |
Leishmania mexicana: Immunology and histopathology in C3H mice |
title_fullStr |
Leishmania mexicana: Immunology and histopathology in C3H mice |
title_full_unstemmed |
Leishmania mexicana: Immunology and histopathology in C3H mice |
title_sort |
Leishmania mexicana: Immunology and histopathology in C3H mice |
author |
Grimaldi Jr., Gabriel |
author_facet |
Grimaldi Jr., Gabriel Moriearty, Pamela Lane |
author_role |
author |
author2 |
Moriearty, Pamela Lane |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Grimaldi Jr., Gabriel Moriearty, Pamela Lane Grimaldi Jr., Gabriel Moriearty, Pamela Lane |
dc.subject.por.fl_str_mv |
Leishmania mexicana Protozoa parasitic Hemoflagellate Mice C3H Leishmaniasis cutaneous Immunofluorescence Indirect hemagglutination Delayed hypersensitivity Ear thickness test Histopathology |
topic |
Leishmania mexicana Protozoa parasitic Hemoflagellate Mice C3H Leishmaniasis cutaneous Immunofluorescence Indirect hemagglutination Delayed hypersensitivity Ear thickness test Histopathology |
description |
Texto completo. Acesso restrito. p. 45 – 56 |
publishDate |
1980 |
dc.date.issued.fl_str_mv |
1980 |
dc.date.accessioned.fl_str_mv |
2013-02-28T16:42:29Z |
dc.date.available.fl_str_mv |
2013-02-28T16:42:29Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.repositorio.ufba.br/ri/handle/ri/8717 |
dc.identifier.issn.none.fl_str_mv |
0014-4894 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 50, n. 1 |
identifier_str_mv |
0014-4894 v. 50, n. 1 |
url |
http://www.repositorio.ufba.br/ri/handle/ri/8717 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Experimental Parasitology |
publisher.none.fl_str_mv |
Experimental Parasitology |
dc.source.pt_BR.fl_str_mv |
http://dx.doi.org/10.1016/0014-4894(80)90006-5 |
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reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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Universidade Federal da Bahia (UFBA) |
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UFBA |
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UFBA |
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Repositório Institucional da UFBA |
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Repositório Institucional da UFBA |
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