Anti-neutrophil cytoplasmic antibodies in leprosy

Detalhes bibliográficos
Autor(a) principal: Edington, Fernando Luiz Barros
Data de Publicação: 2007
Outros Autores: Bacellar, Maria Olívia Amado Ramos, Machado, Paulo Roberto Lima, Barbosa, Lúcio Macedo, Reis, Eliana, Reis, Mitermayer, Santiago, Mittermayer Barreto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/14731
Resumo: Texto completo: acesso restrito. p. 208-210
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spelling Edington, Fernando Luiz BarrosBacellar, Maria Olívia Amado RamosMachado, Paulo Roberto LimaBarbosa, Lúcio MacedoReis, ElianaReis, MitermayerSantiago, Mittermayer BarretoEdington, Fernando Luiz BarrosBacellar, Maria Olívia Amado RamosMachado, Paulo Roberto LimaBarbosa, Lúcio MacedoReis, ElianaReis, MitermayerSantiago, Mittermayer Barreto2014-03-12T17:47:55Z20070770-3198http://repositorio.ufba.br/ri/handle/ri/14731v. 26, n. 2Texto completo: acesso restrito. p. 208-210Introduction: Anti-Neutrophil Cytoplasmic Antibodies (ANCA) are auto-antibodies directed to intracellular components of neutrophils and used to be considered as present almost exclusively in granulomatous vasculitis. Recently, these auto-antibodies have been found in other autoimmune disorders as well as infectious diseases. Materials and methods: We studied patients with leprosy confirmed by bacilloscopy and/or skin biopsy, in reaction phase from the Ambulatório de Hanseníase do Hospital Universitário Professor Edgar Santos. ANCA and Antinuclear antibodies (ANA) were determined by indirect immunofluorescence using commercially available kits. Results: Twenty patients were enrolled in our study, nine males and 11 females. The mean age was 36.9±18.2 years. ANCA were present only in one patient, with a perinuclear staining pattern (p-ANCA), and no patient tested positive for ANA. Discussion: Although other studies have shown the presence of ANCA in leprosy, the low frequency of these antibodies in leprosy sera demonstrated in the present study illustrates the high specificity of ANCA for the diagnosis of Wegener granulomatosis.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-03-12T11:05:19Z No. of bitstreams: 1 art%3A10.1007%2Fs10067-006-0281-7.pdf: 69362 bytes, checksum: 4a4ac3016be606f1034e4f446beef14b (MD5)Approved for entry into archive by Alda Lima da Silva (sivalda@ufba.br) on 2014-03-12T17:47:55Z (GMT) No. of bitstreams: 1 art%3A10.1007%2Fs10067-006-0281-7.pdf: 69362 bytes, checksum: 4a4ac3016be606f1034e4f446beef14b (MD5)Made available in DSpace on 2014-03-12T17:47:55Z (GMT). No. of bitstreams: 1 art%3A10.1007%2Fs10067-006-0281-7.pdf: 69362 bytes, checksum: 4a4ac3016be606f1034e4f446beef14b (MD5) Previous issue date: 2007http://dx.doi.org/10.1007/s10067-006-0281-7reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAAuto-antibodiesHansen diseaseLeprosyVasculitisAnti-neutrophil cytoplasmic antibodies in leprosyClinical Rheumatologyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALart%3A10.1007%2Fs10067-006-0281-7.pdfart%3A10.1007%2Fs10067-006-0281-7.pdfapplication/pdf69362https://repositorio.ufba.br/bitstream/ri/14731/1/art%253A10.1007%252Fs10067-006-0281-7.pdf4a4ac3016be606f1034e4f446beef14bMD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/14731/2/license.txt0d4b811ef71182510d2015daa7c8a900MD52TEXTart%3A10.1007%2Fs10067-006-0281-7.pdf.txtart%3A10.1007%2Fs10067-006-0281-7.pdf.txtExtracted texttext/plain11098https://repositorio.ufba.br/bitstream/ri/14731/3/art%253A10.1007%252Fs10067-006-0281-7.pdf.txtdf6b3b4dd664dcfd9a7863ea7299d1b8MD53ri/147312022-07-05 14:03:17.416oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:17Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Anti-neutrophil cytoplasmic antibodies in leprosy
dc.title.alternative.pt_BR.fl_str_mv Clinical Rheumatology
title Anti-neutrophil cytoplasmic antibodies in leprosy
spellingShingle Anti-neutrophil cytoplasmic antibodies in leprosy
Edington, Fernando Luiz Barros
Auto-antibodies
Hansen disease
Leprosy
Vasculitis
title_short Anti-neutrophil cytoplasmic antibodies in leprosy
title_full Anti-neutrophil cytoplasmic antibodies in leprosy
title_fullStr Anti-neutrophil cytoplasmic antibodies in leprosy
title_full_unstemmed Anti-neutrophil cytoplasmic antibodies in leprosy
title_sort Anti-neutrophil cytoplasmic antibodies in leprosy
author Edington, Fernando Luiz Barros
author_facet Edington, Fernando Luiz Barros
Bacellar, Maria Olívia Amado Ramos
Machado, Paulo Roberto Lima
Barbosa, Lúcio Macedo
Reis, Eliana
Reis, Mitermayer
Santiago, Mittermayer Barreto
author_role author
author2 Bacellar, Maria Olívia Amado Ramos
Machado, Paulo Roberto Lima
Barbosa, Lúcio Macedo
Reis, Eliana
Reis, Mitermayer
Santiago, Mittermayer Barreto
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Edington, Fernando Luiz Barros
Bacellar, Maria Olívia Amado Ramos
Machado, Paulo Roberto Lima
Barbosa, Lúcio Macedo
Reis, Eliana
Reis, Mitermayer
Santiago, Mittermayer Barreto
Edington, Fernando Luiz Barros
Bacellar, Maria Olívia Amado Ramos
Machado, Paulo Roberto Lima
Barbosa, Lúcio Macedo
Reis, Eliana
Reis, Mitermayer
Santiago, Mittermayer Barreto
dc.subject.por.fl_str_mv Auto-antibodies
Hansen disease
Leprosy
Vasculitis
topic Auto-antibodies
Hansen disease
Leprosy
Vasculitis
description Texto completo: acesso restrito. p. 208-210
publishDate 2007
dc.date.issued.fl_str_mv 2007
dc.date.accessioned.fl_str_mv 2014-03-12T17:47:55Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/14731
dc.identifier.issn.none.fl_str_mv 0770-3198
dc.identifier.number.pt_BR.fl_str_mv v. 26, n. 2
identifier_str_mv 0770-3198
v. 26, n. 2
url http://repositorio.ufba.br/ri/handle/ri/14731
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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