Potential of KM+ lectin in immunization against Leishmania amazonensis infection
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2006 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFBA |
| Texto Completo: | http://repositorio.ufba.br/ri/handle/ri/13790 |
Resumo: | Texto completo: acesso restrito. p. 3001–3008 |
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Teixeira, Clarissa RomeroTeixeira, Maria JaniaBarral-Netto, ManoelBarral, Aldina Maria PradoCavassani, Karen A.Gomes, Regis Bernardo BrandimBarreira, Maria Cristina RoqueCavada, Benildo SousaSilva, João Santana daTeixeira, Clarissa RomeroTeixeira, Maria JaniaBarral-Netto, ManoelBarral, Aldina Maria PradoCavassani, Karen A.Gomes, Regis Bernardo BrandimBarreira, Maria Cristina RoqueCavada, Benildo SousaSilva, João Santana da2013-11-19T20:37:56Z20060264-410Xhttp://repositorio.ufba.br/ri/handle/ri/13790v. 24, n. 15Texto completo: acesso restrito. p. 3001–3008In the present study we evaluated Canavalia brasiliensis (ConBr), Pisum arvense (PAA) and Artocarpus integrifolia (KM+) lectins as immunostimulatory molecules in vaccination against Leishmania amazonensis infection. Although they induced IFN-γ production, the combination of the lectins with SLA antigen did not lead to lesion reduction. However, parasite load was largely reduced in mice immunized with KM+ lectin and SLA. KM+ induced a smaller inflammatory reaction in the air pouch model and was able to inhibit differentiation of dendritic cells (BMDC), but to induce maturation by enhancing the expression of MHC II, CD80 and CD86. These observations indicate the modulatory role of plant lectins in leishmaniasis vaccination may be related to their action on the initial innate response.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2013-08-27T12:32:25Z No. of bitstreams: 1 1-s2.0-S0264410X05012892-main.pdf: 364811 bytes, checksum: a7aa8706c19f35fd548a6e19bdd08a62 (MD5)Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2013-11-19T20:37:56Z (GMT) No. of bitstreams: 1 1-s2.0-S0264410X05012892-main.pdf: 364811 bytes, checksum: a7aa8706c19f35fd548a6e19bdd08a62 (MD5)Made available in DSpace on 2013-11-19T20:37:56Z (GMT). No. of bitstreams: 1 1-s2.0-S0264410X05012892-main.pdf: 364811 bytes, checksum: a7aa8706c19f35fd548a6e19bdd08a62 (MD5) Previous issue date: 2006http://dx.doi.org.ez10.periodicos.capes.gov.br/10.1016/j.vaccine.2005.11.067reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBALeishmaniaLectinBone-marrow-derived dendritic cells (BMDC)Potential of KM+ lectin in immunization against Leishmania amazonensis infectionVaccineinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINAL1-s2.0-S0264410X05012892-main.pdf1-s2.0-S0264410X05012892-main.pdfapplication/pdf364811https://repositorio.ufba.br/bitstream/ri/13790/1/1-s2.0-S0264410X05012892-main.pdfa7aa8706c19f35fd548a6e19bdd08a62MD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/13790/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT1-s2.0-S0264410X05012892-main.pdf.txt1-s2.0-S0264410X05012892-main.pdf.txtExtracted texttext/plain33349https://repositorio.ufba.br/bitstream/ri/13790/3/1-s2.0-S0264410X05012892-main.pdf.txt3e2061dbfbc311b2ecd1121f66222db1MD53ri/137902022-07-05 14:02:58.938oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:02:58Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
| dc.title.pt_BR.fl_str_mv |
Potential of KM+ lectin in immunization against Leishmania amazonensis infection |
| dc.title.alternative.pt_BR.fl_str_mv |
Vaccine |
| title |
Potential of KM+ lectin in immunization against Leishmania amazonensis infection |
| spellingShingle |
Potential of KM+ lectin in immunization against Leishmania amazonensis infection Teixeira, Clarissa Romero Leishmania Lectin Bone-marrow-derived dendritic cells (BMDC) |
| title_short |
Potential of KM+ lectin in immunization against Leishmania amazonensis infection |
| title_full |
Potential of KM+ lectin in immunization against Leishmania amazonensis infection |
| title_fullStr |
Potential of KM+ lectin in immunization against Leishmania amazonensis infection |
| title_full_unstemmed |
Potential of KM+ lectin in immunization against Leishmania amazonensis infection |
| title_sort |
Potential of KM+ lectin in immunization against Leishmania amazonensis infection |
| author |
Teixeira, Clarissa Romero |
| author_facet |
Teixeira, Clarissa Romero Teixeira, Maria Jania Barral-Netto, Manoel Barral, Aldina Maria Prado Cavassani, Karen A. Gomes, Regis Bernardo Brandim Barreira, Maria Cristina Roque Cavada, Benildo Sousa Silva, João Santana da |
| author_role |
author |
| author2 |
Teixeira, Maria Jania Barral-Netto, Manoel Barral, Aldina Maria Prado Cavassani, Karen A. Gomes, Regis Bernardo Brandim Barreira, Maria Cristina Roque Cavada, Benildo Sousa Silva, João Santana da |
| author2_role |
author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Teixeira, Clarissa Romero Teixeira, Maria Jania Barral-Netto, Manoel Barral, Aldina Maria Prado Cavassani, Karen A. Gomes, Regis Bernardo Brandim Barreira, Maria Cristina Roque Cavada, Benildo Sousa Silva, João Santana da Teixeira, Clarissa Romero Teixeira, Maria Jania Barral-Netto, Manoel Barral, Aldina Maria Prado Cavassani, Karen A. Gomes, Regis Bernardo Brandim Barreira, Maria Cristina Roque Cavada, Benildo Sousa Silva, João Santana da |
| dc.subject.por.fl_str_mv |
Leishmania Lectin Bone-marrow-derived dendritic cells (BMDC) |
| topic |
Leishmania Lectin Bone-marrow-derived dendritic cells (BMDC) |
| description |
Texto completo: acesso restrito. p. 3001–3008 |
| publishDate |
2006 |
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2006 |
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2013-11-19T20:37:56Z |
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info:eu-repo/semantics/publishedVersion |
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0264-410X |
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v. 24, n. 15 |
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0264-410X v. 24, n. 15 |
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