Headspace solid phase microextraction/gas chromatography–mass spectrometry combined to chemometric analysis for volatile organic compounds determination in canine hair: A new tool to detect dog contamination by visceral leishmaniasis
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/5998 |
Resumo: | Acesso restrito: Texto completo. p. 392-398 |
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Oliveira, Lidia S. deRodrigues, Frederico de M.Oliveira, Fábio Santos deMesquita, Paulo Roberto Ribeiro deLeal, Danielle C.Alcântara, Adriano Costa deSouza, Bárbara Maria Paraná da SilvaFranke, Carlos R.Pereira, Pedro Afonso de PaulaAndrade, Jailson Bittencourt deOliveira, Lidia S. deRodrigues, Frederico de M.Oliveira, Fábio Santos deMesquita, Paulo Roberto Ribeiro deLeal, Danielle C.Alcântara, Adriano Costa deSouza, Bárbara Maria Paraná da SilvaFranke, Carlos R.Pereira, Pedro Afonso de PaulaAndrade, Jailson Bittencourt de2012-05-30T18:21:45Z20081570-0232http://www.repositorio.ufba.br/ri/handle/ri/5998v. 875, n. 2Acesso restrito: Texto completo. p. 392-398A new analytical methodology using HS-SPME/GC–MS was optimized in order to attain maximum sensitivity, using multivariate strategies. The proposed method was employed to evaluate the VOC profile exhaled fromcanine hair samples collected from 8 healthy dogs and from 16 dogs infected by Leishmania infantum. 274 VOCs were detected, which could be identified as aldehydes, ketones and hydrocarbons. After application of the Soft Independent Modeling of Class Analogy (SIMCA) and Principal Component Analysis (PCA) healthy and infected dogs, with similar VOCs profiles, could be separately grouped, based on compounds such as 2-hexanone, benzaldehyde, and 2,4-nonadienal. The proposed method is noninvasive, painless, readily accepted by dog owners and could be useful to identify several biomarkers with applications in the diagnosis of diseases.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2012-05-30T18:21:45Z No. of bitstreams: 1 __ac.els-cdn.com_S157002...93b0c561dc63c3cd50f005ac78284.pdf: 444342 bytes, checksum: 8fc8e0c31b4fab1eef3fa060276704b6 (MD5)Made available in DSpace on 2012-05-30T18:21:45Z (GMT). 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dc.title.pt_BR.fl_str_mv |
Headspace solid phase microextraction/gas chromatography–mass spectrometry combined to chemometric analysis for volatile organic compounds determination in canine hair: A new tool to detect dog contamination by visceral leishmaniasis |
dc.title.alternative.pt_BR.fl_str_mv |
Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences |
title |
Headspace solid phase microextraction/gas chromatography–mass spectrometry combined to chemometric analysis for volatile organic compounds determination in canine hair: A new tool to detect dog contamination by visceral leishmaniasis |
spellingShingle |
Headspace solid phase microextraction/gas chromatography–mass spectrometry combined to chemometric analysis for volatile organic compounds determination in canine hair: A new tool to detect dog contamination by visceral leishmaniasis Oliveira, Lidia S. de Canine hair VOCs HS-SPME/GC–MS Multivariate optimization PCA Diagnosis Visceral leishmaniasis |
title_short |
Headspace solid phase microextraction/gas chromatography–mass spectrometry combined to chemometric analysis for volatile organic compounds determination in canine hair: A new tool to detect dog contamination by visceral leishmaniasis |
title_full |
Headspace solid phase microextraction/gas chromatography–mass spectrometry combined to chemometric analysis for volatile organic compounds determination in canine hair: A new tool to detect dog contamination by visceral leishmaniasis |
title_fullStr |
Headspace solid phase microextraction/gas chromatography–mass spectrometry combined to chemometric analysis for volatile organic compounds determination in canine hair: A new tool to detect dog contamination by visceral leishmaniasis |
title_full_unstemmed |
Headspace solid phase microextraction/gas chromatography–mass spectrometry combined to chemometric analysis for volatile organic compounds determination in canine hair: A new tool to detect dog contamination by visceral leishmaniasis |
title_sort |
Headspace solid phase microextraction/gas chromatography–mass spectrometry combined to chemometric analysis for volatile organic compounds determination in canine hair: A new tool to detect dog contamination by visceral leishmaniasis |
author |
Oliveira, Lidia S. de |
author_facet |
Oliveira, Lidia S. de Rodrigues, Frederico de M. Oliveira, Fábio Santos de Mesquita, Paulo Roberto Ribeiro de Leal, Danielle C. Alcântara, Adriano Costa de Souza, Bárbara Maria Paraná da Silva Franke, Carlos R. Pereira, Pedro Afonso de Paula Andrade, Jailson Bittencourt de |
author_role |
author |
author2 |
Rodrigues, Frederico de M. Oliveira, Fábio Santos de Mesquita, Paulo Roberto Ribeiro de Leal, Danielle C. Alcântara, Adriano Costa de Souza, Bárbara Maria Paraná da Silva Franke, Carlos R. Pereira, Pedro Afonso de Paula Andrade, Jailson Bittencourt de |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Oliveira, Lidia S. de Rodrigues, Frederico de M. Oliveira, Fábio Santos de Mesquita, Paulo Roberto Ribeiro de Leal, Danielle C. Alcântara, Adriano Costa de Souza, Bárbara Maria Paraná da Silva Franke, Carlos R. Pereira, Pedro Afonso de Paula Andrade, Jailson Bittencourt de Oliveira, Lidia S. de Rodrigues, Frederico de M. Oliveira, Fábio Santos de Mesquita, Paulo Roberto Ribeiro de Leal, Danielle C. Alcântara, Adriano Costa de Souza, Bárbara Maria Paraná da Silva Franke, Carlos R. Pereira, Pedro Afonso de Paula Andrade, Jailson Bittencourt de |
dc.subject.por.fl_str_mv |
Canine hair VOCs HS-SPME/GC–MS Multivariate optimization PCA Diagnosis Visceral leishmaniasis |
topic |
Canine hair VOCs HS-SPME/GC–MS Multivariate optimization PCA Diagnosis Visceral leishmaniasis |
description |
Acesso restrito: Texto completo. p. 392-398 |
publishDate |
2008 |
dc.date.issued.fl_str_mv |
2008 |
dc.date.accessioned.fl_str_mv |
2012-05-30T18:21:45Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
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publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.repositorio.ufba.br/ri/handle/ri/5998 |
dc.identifier.issn.none.fl_str_mv |
1570-0232 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 875, n. 2 |
identifier_str_mv |
1570-0232 v. 875, n. 2 |
url |
http://www.repositorio.ufba.br/ri/handle/ri/5998 |
dc.language.iso.fl_str_mv |
eng |
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eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
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http://dx.doi.org/10.1016/j.jchromb.2008.09.028 |
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reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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UFBA |
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UFBA |
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Repositório Institucional da UFBA |
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Repositório Institucional da UFBA |
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